Chromosome losses mean poor survival in childhood leukemia
...ernational study of children with a severe form of acute lymphoblastic leukemia (ALL) shows that certain ch...ukemia, and it accounts for about one-fifth of all acute leukemias in adults. About 80 percent of children with ALL have a curable form of the disease, while...Other highlights in the May 5 JNCI
... drugs, such as prednisone, that are used to treat acute and chronic inflammatory diseases. Henrik Toft Srensen, M.D., Ph.D., of Aarhus University Hospital in Aarhus, Denmark, and colleagues identified 59,043 individuals from the North Jutland Prescription Database--a computerized pharmacy database of pr...New research outlines public health consequences
...disaster." Previous studies have documented the acute traumatic consequences of the September 11 attacks, most notably the occurrence of 2,726 deaths, including 343 firefighters and 60 police officers. Early clinical assessments noted a high prevalence of respiratory symptoms, including persistent cough...Kinase backgrounder: Iressa discovery part of major kinase project at Dana-Farber
...activity against a type of adult leukemia known as acute myelogenous leukemia. It is about to be tried in infants. "We think that many, probably most, cancers involve mutant kinases," says Roberts. "I can't promise you that every kinase has an inhibitor, but I think it's going to be much closer to the rule...Cells from adult bone marrow can be converted into brain stem cells for transplantation
...tential of the converted cells in animal models of acute and chronic neurodegenerative disorders, such as stroke and Parkinson's disease. The researchers also need to determine the best way to administer the cells into the brain....Gene defect linked to premature aging
...cell growth and mutated forms of the gene occur in acute leukemias. Using genetically engineered mice, Arceci's team knocked out part of the "core engine" of the PASG gene, decreasing methylation throughout the genome and allowing the wrong genes, particularly those associated with premature aging, to be ...Chlamydiae infection may be associated with ocular adnexal lymphoma
...uding chlamydia, and Chlamydia pneumoniae causes acute respiratory tract infections. Both of these species have been shown to be associated with cervical cancer and lung cancer, respectively. Infection with a third species, Chlamydia psittaci , results from exposure to infected birds and possibly other ...Insights on stroke from the peripheral blood suggest ways to develop markers and therapies
...echanisms involved in the etiology and response to acute stroke, ultimately leading to new drug therapies or preventive vaccines. Blood studies are infinitely faster and more practical than looking at brain tissue samples from biopsy or post-mortem, and have the added advantage of being available serially ...Study is another step in determining if curry can protect against Alzheimer's
...ng whether curry could be preventive agent against acute neurodegenerative conditions, or reducing the prog...r curcumin can be used as preventive agent against acute neurodegenerative conditions that affect an increasingly aged population....Is a single bout of exercise helpful or harmful in getting a good night's sleep?
...ty and length of sleep obtained after non-habitual acute resistance and aerobic exercise. Of interest was whether a single workout would be beneficial or harmful in obtaining restful sleep the night following the exercise. A New Study The authors of "Non-Habitual Acute Resistance and Aerobic Exercise A...High-fat fast-food breakfast produces rush of inflammatory factors into blood stream, UB study finds
...e lining of blood vessels. "The magnitude of this acute and transient effect is dependent on the type of macronutrient and may lead eventually to a chronic pro-inflammatory and pro-oxidative state, as seen in obesity," said Aljada. "This, in turn, leads to several medical complications." The study was c...APS announces four 2004 Young Investigators awards
...echanisms of inflammation and edema, a hallmark of acute respiratory distress syndrome. Armin Just, M.D., Ph.D. University of North Carolina The Arthur C. Guyton Award for Excellence in Integrative Physiology An award of $15,000 will be made on Dr. Just's behalf to the University of North Carolina....Genetic screening study at Stanford ID's most aggressive adult leukemia strains
... that point to the most dangerous strains of adult acute myeloid leukemia, or AML. Their research, publishe...ent for their AML patients. AML is the most common acute form of leukemia in adults. In devising a treatment plan, a doctor relies on indicators such as how ...Scripps research scientist wins 2004 Koch Prize
...ple who come down with a kind of severe sepsis, an acute and often deadly disease. A graduate of the University of California, San Diego, Beutler received his medical degree from the University of Chicago. He has been a professor at Scripps Research since 2000. Prior to that, he had been a Professor...GenVec, U.S. NMRC, and PATH's Malaria Vaccine Initiative partner to expand malaria vaccine efforts
...a, and death. Malaria causes more than 300 million acute illnesses and over one million deaths annually, mostly among children under the age of five. Malaria is also a major health risk for travelers and the military....Study points to a promising new test for myelodysplasia, a blood disorder often leading to leukemia
... disorder that can lead to bone marrow failure and acute myelogenous leukemia. Myelodysplastic syndrome (M...ts over 60 years of age. Those who do not develop acute leukemia may later go on to die from infection or bleeding. Treatment options are not always succes...Scientists crack genome sequence of a major parasitic pathogen
... through feces of infected hosts and results in an acute case of diarrhea in humans and animals. Most people with an intact immune system recover after several days; however, for the young, elderly, and immunosuppressed individuals, symptoms can be severe and require intravenous fluid therapy to deal with ...Estimated one in five people worldwide lack enough zinc in diet
...ence of diarrhea and 40% reductions in the rate of acute lower respiratory infections, like pneumonia. These diseases are among the most common causes of child mortality in developing countries. Early evidence indicates that mortality rates are reduced by 50% or more among zinc-supplemented children in ...Study reveals important new factor in cystic fibrosis lung inflammation
...molecules do what we'd like them to do -- suppress acute inflammation, switch on the chronic inflammatory p...ase, but it is." Inflammation in the CF airway is acute inflammation -- inflammation dominated by neutrophils, which are white blood cells that serve as a f...Gene chips help gauge chemotherapy's effectiveness in adult leukemia patients
... who had recently been diagnosed with adult T cell acute lymphocytic leukemia (T-ALL), a disease caused by the overproduction of immune cells known as T lymphocytes. "The present study investigates, for the first time, the identification of gene expression profiles associated with both short-term and long-...