Enzyme's "Magic" May Hold Key to Anticancer and Antimicrobial Drugs
...t DNA segment. Figure adapted from Nature , 18 January 1996, 379, p. 231 with permission. Because drugs act on specific enzyme conformations, knowledge of these conformations has significant implications in drug design. "Topoisomerase is...Duke Researchers Show "Editing" Can Fix Faulty Genes In New Approach To Gene Therapy
...again. Sullenger reasoned that ribozymes could be adapted as atool to recognize defective mRNA and splice in a corrected version. To accomplishthis, he turned to the first ribozyme discovered, from the single-celledorganism Tetrahymena thermophila . This ribozyme not only cuts otherpieces of RNA at specifi...Hawaiian Whales Show 'No Overt Response' To Sounds Of ATOC Simulation
...ornell for examining bird sounds, and which is now adapted by researchers around the world -- not only to analyze vocalizations of animals of all kinds, but also seismic events, including underwater earthquakes as well as tornadoes and even heart EKGs. "Whales are individuals, just like people, and some app...NCAR Scientist Models Earth's Climate and Vegetation Patterns At Last Glacial Peak
...ranked the vegetation by which plant type was best adapted to which regional climate. It computed how much surface area each type occupied based on competition for light (related to canopy cover) and disturbances such as tree fall and lightning-sparked fire. The result was a global picture of vegetation 21,0...Researchers Develop Model Using Birds As Indicator Of Wetlands Health
...o ifyou find many water-loving birds and few birds adapted to drierhabitats, that's an indication that the wetland environment isthriving. Birds are also fairly easy to track. "If you look at butterflies or certain insects, that wouldgive a more direct indicator," said David Styer, a professor ofmathematics ...New Sensor Provides First Instant Test For Toxic E. coli Organism
...private company. And then, it must be refined and adapted for mass manufacture and sale. Stevens, who is also an assistant professor of chemistry at the University of California at Berkeley, developed the sensors in concert with Berkeley postdoc Quan Cheng. The device is a modification of one originally des...Duke University Students Devise Devices For The Disabled
...ol. The base of Daniel's hockey goalie slider was adapted from the heavytrack of a professional Olympic rowing machine that Feldman managed to securefor free from Concept II Rowing Co. in Morrisville, Vt. "Dr. Bohs went to graduate school at Dartmouth with a colleaguewho ended up marrying the president of ...A Drug Pump On A Computer Chip
..., who himself is diabetic, hopes his device may be adapted as a closed-loop system for monitoring blood glucose levels and pumping just the right amount of insulin into the bloodstream. "Ideally, an insulin delivery pump would sense the patients blood glucose level and change the dose of insulin accordingly,...Houseflies May Transmit Ulcer Bug
...says Dr. Grbel. "Structurally the fly is well adapted for picking up pathogens,"says Dr. Grbel. "Its proboscis is provided with a profusion of fine hairsthat readily collect environmental detritus. Furthermore each of the sixfeet of the fly is fitted with hairy structures and pads that secrete a stick...Low Iron Levels Cause Weakness In Women Who Are Not Anemic
...untries with serious anemia problems, once we have adapted these indicators of functional impairment for field use," Haas said. To improve iron status through diet, Haas and Zhu recommend eating red meat. For vegetarians, they recommend consuming orange juice (vitamin C) with meals to improve absorption fro...Fighting Wheat Scab In New York State
...d occurrence of scab, Bergstrom said. "All of our adapted pastry wheat varieties are susceptible to scab, which is most severe when wet weather occurs while the crop flowers in late May-early June," he said. Fortunately, wet weather was not encountered during wheat flowering this year in New York, and preli...Oak Regeneration In Some Ohio Forests Is Failing, Researchers Find
... of species that live in these types offorests are adapted to living in an oak forest," McCarthy said. "If there is amajor change in the habitat, there could be system-wide effects on all thespecies of insects, birds and mammals that live there, possibly even to thepoint that some species of animals or plant...Limits Of Life On Earth: Are They The Key To Life On Other Planets?
... can provide new insights into how these organisms adapted to diverse environments, and shed light on the limits within which life can exist." NSF's directorates of biological sciences; engineering; geosciences; mathematical and physical sciences; and office of polar programs are providing total funding...Widespread Genus Of Monkeys Gives Up Genealogical Secrets To Columbia Researchers
...logists more about how other mammals dispersed and adapted to the sameconditions. Among the many fi...boons, mangabeys and mandrills. The macaques have adapted to awide range of conditions, finding ecological niches at sea level and at 12,000feet, from semi-de...At Life's Most Sensitive Stage, Embryos Cope With Stress
... developed the adult'smechanisms for coping. It is adapted to a particular niche and to a particulartask - rapid cell division and development. One purpose of this symposium is tolook at how the rules and principles for handling stress appear to be differentfor embryos than for adults." Spitting out toxins E...When To Reproduce? It's All In The Timing
... it is relative to selectivemechanisms or how well adapted it is to the community it lives in." -30-...New Sensor Will Detech Chemical And Biological Pathogens At Incredibly Small Doses
...landar expanded upon some of his previous work. He adapted a technology he invented that is employed to purify pharmaceuticalspresent in blood plasma at trace levels. By combining his scientific processwith an optical fiber sensing device, Velander and Murphy have found that theycan "capture biological warfa...Computer Models Find Cost-Effective Solutions For Species Preservation
...eland provide alternatives." The model can even be adapted worldwide. "If they want to dothis in Europe, the basic model is there," said Camm. "What wouldchange is how you define a piece of land. It might not becounties. It might be some other designation." "You simply have to have a way of breaking a map do...Caribbean Lizards Evolve Independently
...Caribbean anole species indicate that species have adapted to use differentparts of the environment by evolvi...tion. Based on their knowledge of how species have adapted over millions of years todifferent habitats, they predicted that these populations should develop sh...Pitt Researchers Develop Strategy To Use Dendritic Cells To Treat And Prevent Tumors
...hich suggests that this model could potentially be adapted for usein the clinical setting to treat patients," commented Louis D. Falo, Jr., M.D.,Ph.D., assistant professor of dermatology, vice chairman of dermatology at Pittand member of the University of Pittsburgh Cancer Institute (UPCI). "Usingtumor cell...