Antisense Therapy Prevents Burkitt's Lymphoma In Mice
... nucleic acid therapeutics orvectors." He adds that "the ability to turn off or correct individualdisease-causing genes, or to replace them at will in a patient's cells providesa powerful therapeutic intervention in genetic diseases. Gene-specific nucleicacid therapy has gone from theory to pract......esearch ought to lead to sometreatments for CMTX," adds Scherer. "We ought to be able to someday designtherapies based on our growing knowledge of how the mutations affect the sheathand the passage of ions through gap junctions." So far, the team has been ableto express in transgenic mice both normal and ...Commercial Fish: Eat Up, Despite Low Levels Of Mercury
... face the risk ofheart disease," says Clarkson. He adds that FDA's currentguideline already helps people avoid excessive mercury exposure,which would be a danger primarily for someone eating frequentmeals of fish like swordfish and shark. Fish are the primary source of exposure to mercury aroundthe w...Gene Mutation Found For Common Form Of Mental Retardation
...erything is where it shouldbe," Walsh says, but he adds that such gross images would not reveal defects incell shape. In general, the appearance of males with the MRX defect ismisleading. Despite their profound behavioral disabilities, delayed and primitivespeech as well as severe learning and social impa...Research Team Finds Gene Causing Two Types Of Muscular Dystrophy
...trophy may result from mutations in this gene." He adds that identifying the gene will help improve diagnosis of theseparticular disorders and eventually could lead to treatment methods that addressspecific muscle defects. The muscular dystrophies are genetic diseases characterized by progressiveweakness ...Possible Dangers Of Taking Over-The-Counter Medications For Hepatitis C Patients
...es, suggesting significantliver injury. He adds that if too much medication is taken the patient risks speedingup the process of going from chronic hepatitis to cirrhosis of the liver. Riley says that about four million Americans are infected with hepatitisC. Some of the more common ways i...Jurassic Beetle: CSIRO Entomologist Discovers Living Fossil
...ything anywhere," he says. In fact, Dr Lawrence adds wistfully, it would be interesting to study the insects that have survived on the Wollemi pine itself. There must be a few more Jurassic-era specimens there for the finding too. But so far, the trees' location remains a close-held botanical sec...Upcoming 'Century Of Biology' Given Head Start By NSF Plant Genome Research Program Grants
...d fertilizer requirements, andbetter quality food, adds Coe. "The end result is a better quality of life, notonly for us, but for the entire planet." In other research, scientist Thea Wilkins of the University ofCalifornia at Davis will study the genome of the world's leading natural fiber,cotton......al curricula." The public also can create demand, adds Dr. Heimburger. "the american public's expectations for nutrition information related to health are increasingly sophisticated and they should expect the same from their physicians. The presidents of the nutrition organizations that publish the Ame......sms that makealcohol habit-forming, but this study adds significantly to the accumulatingevidence that has suggested a role for the dopamine systems, already known toplay a role in habit-forming properties of heroin and cocaine," says Roy Wise,PhD, an addiction expert at the National Institute on Drug Abu...Cell Suicide Prevented By Survival Signals
...athways, Ras turns on the enzyme MAP-kinase, which adds aphosphate group to specific proteins, including Hid. "Hid is harmless as long as it is phosphorylated, but if survivalsignaling drops or disappears, unphosphorylated Hid accumulates and thatleads to apoptosis," Steller says. He notes that the hi...American Society Of Animal Science Recognizes Global Scope Of Virginia Tech Researcher's Work
...rk falls into the category of basic research,which adds to the foundation of knowledge of a subject. Other parts of his work,however, are applied research, or research in ways to make basic understandingdirectly useful to producers. "I enjoy doing applied, producer-applicable research," Notter sai...Virginia Tech Scientist Seek Genetic Solution To Malaria
...niversity. With her program, Virginia Tech adds a new dimension to the transgeniccapabilities of the university's biotechnology effort. Other Virginia Techresearchers have gained international attention for pioneering work indeveloping transgenic plants and animals for the production of pharmaceut...Brain Study Sheds Light On The 'Phantom Limbs' Of Amputees
...heir 60s and 70s, grow new brain cells, the report adds to thegrowing awareness that the adult brain is far more responsive and adaptable thanhad been believed. Jones and Pons studied the brains from eight monkeys in which, 12 to 20 yearsbefore their deaths, the nerves in one arm had been surgically sever......e bacteria from becoming virulentand killing you," adds Petsko, who was not involved in this work. Once 95 percent lethal, diphtheria is no longer a major concern in the developedworld. But the former Soviet Union has experienced a sharp recurrence of thedisease during the 1990s, and public health officia...Genetic Code Of Chromosome Of Malaria Parasite Deciphered
...encing the entire genome ofPlasmodium falciparum," adds Michael Gottlieb, Ph.D., Parasite Biology ProgramOfficer at NIAID. "The researchers have identified more than 200 genes, many ofwhich are probably essential to parasite functions, including genes that mediateinteractions with host cells and contribu......® to be effective againstmultiple forms of HCV adds significantly to its potential as a therapeutic agentagainst HCV. We look forward to developing HEPTAZYME® aggressively, and hopethat it will become an important component in anti-HCV treatment regimens," saidDr. Ralph Christoffersen, Ph.D., CEO...Brookhaven, Carnegie Scientists Report First 'Morphing' Of Plant Enzyme Function
...single chemicalbonds into double ones. Hydroxylase adds hydroxy groups to the fatty acids'structure. These simple chemical changes can make huge differences in plant oilproperties. For example, a fatty acid molecule with two bends may be sensitiveto heat, while a fatty acid with an added hydroxy...Scientists Finger A Molecular Kingpin In Body's Response To Cigarettes
...t factor mediating genetic damage fromcigarettes," adds Dertinger. The findings complement recent work by other researchers whohave shown that people with an abundance of enzymes known asCYP1A1 or P450 cytochrome molecules are more prone to developingcancer from smoking. The AH receptor turns on thes...