Stem cells toward sperm cells and back again
...artificially triggered reversal of cell fate in an adult creature. "With a few exceptions, it is thought that once cells start down the path toward specialization, they can't go back," says Erika Matunis, Ph.D., assistant professor of cell biology in Hopkins' Institute for Basic Biomedical Sciences. "But ...When 'reaper' gene comes, cell death follows
...truction of larval tissue and their replacement by adult structures. Ecdysone already was known to regulat...trigger that changes Drosophila from its larval to adult form," he said. To identify roles for reaper and hid in cell death, Yin and Thummel used a combinat...Dramatic decline of California native frog linked to introduced trout in mountain lakes
...he tadpoles in a lake. The delay in the decline of adult frogs is most likely due to the fact that they pro...s of tadpoles would not produce a dramatic drop in adult frogs for a decade or longer. As part of his study, he and UC Berkeley undergraduate volunteers remo...Regeneration of injured muscle from adult stem cells
...rcise or injury and harbors two different types of adult stem cells to accomplish the job: satellite cells and adult stem cells that can be isolated as side population (SP) cells. A certain group of these stem cells ...First time in the U.S.: Saint Louis University tests third-generation vaccine against smallpox
...n insulin shot is given. The study will enroll 90 adult volunteers into six different groups. MVA-BN will be given in three different dose strengths alone or in combination with Dryvax. The study is sponsored by the National Institute of Allergy and Infectious Diseases. Volunteers must be between 18 and 3...Tests show biotech corn rules need revision
...t corn are rare at first, and only a few resistant adult moths emerge from Bt corn fields. But refuges of non-Bt corn produce oodles of susceptible moths. The idea is that the uncommon resistant moths will mate with the more abundant susceptible moths. Their hybrid progeny would be killed by feeding on Bt ...Once a renin cell, always a renin cell
...nia and colleagues examined whether the ability of adult cells to synthesize renin was dependent on the cel...o recruit renin-expressing cells demonstrated that adult cells that were descendants of renin cells retained the capability to make renin when more of the ho...Treatment stimulates growth and regeneration of injured adult skeletal muscle
...C) inhibitors stimulate growth and regeneration of adult skeletal muscle cells by increasing expression of ... reduced, then HDAC inhibitors no longer stimulate adult muscle growth. The regeneration activities of the HDAC inhibitors appear to function only in skeleta...Parent-offspring conflict in the evolution of vertebrate reproductive mode
...or the evolution of genes that promote cancer, and adult health increasingly appears to be 'programmed' during fetal development....Dampened hopes for transplanting bone marrow stem cells in heart attacks
There is little, if any, evidence that adult stem cells can build other cells in an adult organism than those formed in the organs they themselves come from. At any rate, blood stem cells d...Tiny beetle wreaks havoc on Texas ornamental tree nurseries
...ted that mild winters have played a big role. The adult beetles over-winter in leaf litter, and warmer winters could result in more surviving to emerge in the spring, he said. "But that's just conjecture at this point. We don't know for sure," Ludwig said. Ludwig noted a few products are labeled for use...Insulin-producing pancreatic cells are replenished by duplication
...sting cells rather than through differentiation of adult stem cells. Although the experiments, which were...ce, do not rule out the possibility that there are adult stem cells in the pancreas, the researchers say that they do suggest strongly that embryonic stem ce...Chromosome losses mean poor survival in childhood leukemia
...sometimes occurs in several types of childhood and adult leukemias. It arises when a piece of chromosome 9 fuses with a chromosome 22. The fusion results in an abnormal protein that plays an important role in the malignancy....Fat cells heal skull defects in mice, Stanford research shows
...ted from fat pockets under the skin of juvenile or adult animals. They've found that the cells, also known as multipotent cells, can be coaxed in the laboratory to express the genes and characteristics of many other tissue types, including bone, cartilage and muscle cells. But it was not known if these cel...First target for childhood malaria vaccine
...hat cause severe childhood malaria and less severe adult infection, respectively. They identified one prote...lls during severe childhood malaria but not during adult infections. This protein causes infected red blood cells to stick inside blood vessels, preventing t...Study detects protein in human milk linked to reduced risk of obesity
...reme growth and development, may have an impact on adult disease." The researchers also confirmed the presence of leptin in human milk. Leptin is another protein produced by fat that appears to play an important role in the regulation of body fat. Leptin is a satiety hormone, involved in the state of bei...Kinase backgrounder: Iressa discovery part of major kinase project at Dana-Farber
...linical trials, showing activity against a type of adult leukemia known as acute myelogenous leukemia. It is about to be tried in infants. "We think that many, probably most, cancers involve mutant kinases," says Roberts. "I can't promise you that every kinase has an inhibitor, but I think it's going to be...In male monkeys, too much soy has adverse effects
...aplan said. The study was done over 15 months with adult male monkeys who were divided into three groups and fed different amounts and types of protein. One group had about 125 mg of isoflavones a day. The second group had half that amount, and the third group's protein came from milk and animal sources. ...Cells from adult bone marrow can be converted into brain stem cells for transplantation
...April 24 May 1, 2004, shows that cells taken from adult human bone marrow can be converted into brain stem...sity of Ulm in Ulm, Germany. Use of the cells from adult human bone marrow, called stromal cells, eliminates the ethical and logistical issues that arise wit...University of Pittsburgh receives NIH funding to develop heart assist device for infants
...st devices (VADs) that have been designed with the adult patient in mind, but no devices currently approved...AD must be more than just a smaller version of the adult devices. It also must be designed to meet the special medical and circulatory needs of infants with ...