Tag: "affects" at biology news

New targets for nerve diseases, nerve regrowth: It's all in the handshake

...than-normal gangliosides byeliminating a gene that affects molecule length. This action blocked attachmentof a protein-attractive portion at one end of the ganglioside. A microscopic study of brain, spinal cord and peripheral nerves in theknock-out mice showed a deterioration whose onset came as ...

Salamanders may one day monitor degradation in small streams

...tors say little about how environmentaldegradation affects animal populations. Because these salamanders are lungless,breathing through their skin and the linings of their mouths, they can be verysensitive to changes in their aquatic and terrestrial environments. Also, somespecies lay eggs on land while othe...

New components of machinery that carries genetic information from nucleus

...be determined is whether IP6 directly orindirectly affects the transport of mRNA from the nucleus. IP6 may m...ein that is the target ofthe IP6 signal and how it affects that protein to act as a switch. More broadly,the discovery of the two kinases has helped open up an...

Head trauma damages DNA repair mechanism

...ted degradation of PARP,which ultimately adversely affects the repair of damaged DNA. Essentially, an injured cell's internal observation system for detectingdamage breaks down and cellular repair crews are never called into action. "Ifthe body can't detect that DNA has been fragmented, the repair mechan...

Mice show function of gene that causes two types of blindness

...nfour adults over 65. Stargardt's disease affects about one in 20,000 children over age 6, andage-related macular degeneration (AMD) develops in approximately one in fouradults over 65. Both disorders affect central vision, which enables reading,driving and face recognition. The work is a major step...

Drug users, Native Americans susceptible to infectious diseases

...lated to the virus that causes bovine leukemia, it affects thesame lymphocytes as HIV. The researchers speculate that their present work onthe biological mechanisms of HTLV could lead to a better understanding of theAIDS virus. "Understanding how HTLV works will fill out the knowledge of humanretroviruses,"...

Discovery might boost cystic fibrosis therapy

...saltwater inaerosol form." Cystic fibrosis affects about 30,000 children and young adults in theUnited States. When two carriers of a defective gene known as CFTR producechildren, on average one in four of their children will have the disease, twowill be carriers like their parents and one will be di...

Mechanical forces found to exert larger role in blood vessel health and disease

...on to promoting thegrowth of new blood vessels, it affects the ability of the cells on the interiorsurface of...ociates haveshown that it exerts shear stress that affects vessel function. For example,they have found that shear stress from transmural fluid flow stimulates...

$6.75 Million to extend primate studies of diet and aging

MADISON - A decade-long study of how diet affects the process of growingold, will continue and be expanded at the University of Wisconsin-Madisonwith the help of $6.75 million from the National Institutes of Health (NIH). Begun in 1989 at the Wisconsin Regional Primate Research Center (WRPRC),the st...

Researchers suggest new mechanism to explain DNA charge transfer process

...w is to try to understand how the structure of DNA affects its charge transport," Schusterexplained. "We have a suspicion that one or another ofDNA's many structural forms might be a better conductor than the standard form that researchers have been lookingat. DNA is a flexible structure, and the different...

Scientists discover second gene for disorder described by Darwin

...uceabnormal development. However, if the mutation affects the internal portion,the result is similar to the "one bad apple spoiling the barrel" phenomenon. The defective piece of protein inside the cell could bind up functional sistermolecules, essentially short-circuiting the switch mechanism and aborting ...

Narcolepsy gene identified

...he number of episodes, there is nocure. Narcolepsy affects males and females equally, and the condition tends torun in families. Yanagisawa's team's discovery, along with a paper in the August 6, 1999,issue of Cell that describes research on narcoleptic doberman pinschersby researchers at Stanford Univer...

UT Southwestern researchers create mice with narcolepsy

... cure or long-termtreatment for the illness, which affects 200,000 Americans and can alter social,personal and professional activities because those suffering from it frequentlyfall asleep at inappropriate times. Knowing what causes narcolepsy could lead totreatments. The research will be published i...

Microbial janitors tackle nuclear clean-up problems

...am. She started outstudying how soil microbiology affects the stability of buried cement wasteforms. The research team quickly realized that the problem of microbialdegradation could be put to good use actually treating contaminated concrete. This technology could significantly reduce waste treatment costs...

Hepatitis E virus infection may be widespread in rats

...ine in Honolulu, HI. Hepatitis E disease generally affects young adults and usually is notlife-threatening, except in pregnant women infected with the virus wherefatality rates of 15 to 20 percent have been reported. According to the Centersfor Disease Control and Prevention (CDC), virtually all cases of he...

Gulf Coast environmental issues -- Tip sheet

...ncludetoxic compounds in Gulf oysters, how weather affects ozone levels in the region,and the quality of Mississippi River water. All papers are embargoed until thetime of presentation, unless otherwise noted. Toxic Compounds in Oysters - Tributyltin (TBT) - a biocide used primarily onship hulls, docks an...

'Knockout' mouse may lead to major understanding of human kidney disorder

...eatment of IgA nephropathy, a kidney disorder that affects hundreds ofmillions of people throughout the world. The advance, appearing in theSeptember issue of Nature Medicine, represents what may be one of the mostpromising applications of "gene knockout" technology to date. The study was conducted...

Disconnecting molecular handbrakes has drastic consequences

...s the differentiation of T cells in the thymus and affects theaction of those cells elsewhere in the body. The data from the experiments indicated that SOCS1 performed threefunctions, said Ihle. "In the thymus, the gene probably plays a major role inthe differentiation of T cells," he said. "And it may ne...

Snapshot of new drug marks a major advance by Memorial Sloan-Kettering researchers

... MSKCC researchers, closely fits into anenzyme and affects how it regulates cells. By visualizing how the drug, calledSAHA, nestles into the active site of the enzyme and subtly alters itsstructure, the picture will enable investigators to make more potent and morespecifically targeted versions of these dru...

Experts take aim at Montezuma's revenge at conference organized by UM school of medicine

... is of special concernto the military, because "it affects 20 to 30 percent of military personneldeployed overseas," according to Harry L.T. Mobley, Ph.D., professor ofmicrobiology and immunology at the University of Maryland School of Medicine. "Developing a safe and effective vaccine is a high priority ...

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