Discovery Of Genetic Pathways May Provide New Ways To Combat Candida Infections
...e. For one, developing broad spectrum antibiotics against fungi has been difficult. Fungi are more similar ...ages in petri dish, which are normally ineffective against filamentous Candida. When challenged by Candida strains with both pathways knocked out, macrophages...Molecular Piracy Turns Protein Into Traitor
...cules. The virus then tested the related molecules against our own immunological defence mechanisms, making modifications until it found a molecule with the desired properties. In this particular case, the virus was hunting for a molecule that would prevent an inflammatory immune response that might clear th...Planned Burning In Forests A Boon To Several Species Of Birds In Illinois
...cies go down in abundance," hesaid. "Fire selects against those species, but it enhances some otherspecies." Among the species benefiting in Illinois is thered-headedwoodpecker -- whose presence in the Midwest has declined almost 2 percenta year since 1966 -- as well as northern orioles, summer tanagers, r...Trojan Horse Virus Controls Hiv Infection
...s, ortherapeutic genes to protect uninfected cells against an invading virus. Moreover, such vectors could be... as dendritic cells,for mounting immune protection against an invading pathogensuch as HIV. NIAID, a component of the National Institutes of Health (NIH), s...Finished Your Lunch? Now Eat The Wrapper
...w shaping up as a very importantdietary protection against cancer and other bowel diseases, which are respons...mple chemicals or even bacteria which help protect against cancerand other diseases could be encased in the resistant starch, which willthen carry them safely ...Chemists Develop High-Throughput Method To Synthesize And Screen Novel Antibiotics
...Day. "Most ofthem test out as being very effective against a wide range ofbacteria." More importantly, severa...sistant and non-resistant strains of bacteria, and against a"defanged" version of the microbe that causes tuberculosis. The results were encouraging, although...Mutant Gene Not Sole Explanation For Hiv Non-Progression
... have made to science and the fight against AIDS is immeasurable." Dr. Cohen's and Fauci's collaborators include Mauro Vaccarezza, M.D., Gordon K. Lam, Barbara F. Baird, Kathryn Wildt, Philip M. Murphy, M.D., Ph.D.,...Smoking Mice Lead To Emphysema Breakthrough
...cepted scenario, neutrophilsmount a counter-attack against smoke by congregating in the lungs and releasinginflammatory enzymes. The enzymes eventually break down elastic fibers in thelungs, causing a new case of emphysema. But the prevailing theory had a shortcoming: lungs with emphysema don'thave m...At-Risk Women Want Breast Cancer Gene Test--If 'Pros' Outweigh 'Cons'
...ight use the results of such tests to discriminate against those who carry themutant genes. Despite this, most women in the study perceived relatively fewdisadvantages from genetic testing. As might be expected, their concerns were related primarily to thepossibility of learning they had inherited...NIH Office Of Dietary Supplements Expands Research Support
...e is a substance that may have a protective effect against dietary and bacterial toxins found in infants whose intestinal function may be impaired by disease. In addition to these three new projects, the ODS will continue its support of five studies begun in 1996, two with the National Institute of Arthrit......nfect thevery cells tasked with defending the body against infection. The protein product of one of t..., in a further blow to the body'sability to defend against the infection, Vpr actively induces apoptosis inneighboring immune system cells that have not yet be...Competitive Inhibition May Enhance Safety Of Minimally Processed Fruits And Vegetables
...tering, and in refrigerated meat products to guard against spoilage. For a copy of the article or Sept. 1997 issue of Food Technology, contact AngelaDansby at (312) 782-8424 X134....Photocatalytic Air Cleaning System Promises To Help Allergy Sufferers
...ufferers soon may have a new weapon in their fight against airborne enemies: an indoor-air cleaning system that uses light and simple chemicals to destroy the dust mites and mold spores that cause many allergies. Developed at the University of Florida's Solar Energy and Energy Conversion Laboratory, ...Oral Vaccine Protects Infants From Severe Rotavirus Diarrhea
An oral vaccine against rotavirus -- the most important cause oflife-threa...though the vaccine was only 48 percent efficacious against a first episode ofrotavirus diarrhea of any severity, the vaccine reduced the incidence of severerot...Jefferson Scientists Develop Botulism Vaccine
...ity, Philadelphia, have created an oral vaccine against botulism. The researchers believe that such a v...the novel molecule is an effective oral vaccine against botulism. The scientists, reporting in November in the journal Infection and Immunity, detail t...Recombinant Protein Immunizes Mice, Promises New Strategy Against Infection And Cancer
...lications for developing safe vaccines to immunize against AIDS and otherinfectious diseases, and for creatin...e response againstovalbumin and developed immunity against cancer cells that make ovalbumin. These ovalbumin-producing cancer cells normally kill unimmunized m...SFU Researcher Fools Forest Pest Into 'Barking Up The Wrong Tree'
...rk beetle's superb sense of smell may soon be used against it. Researchers plan to use the non-host scents to disguise trees that thebeetles would normally attack. "In an area where we know bark beetles are present, we'd, say, make a Douglas fir smell like a cottonwood," says Huber. "Instead of attacking the...Cut Pesticide Use In Half, Urges SFU Biologist
...d manage. The extent of the chemical warfare against pests is "staggering,"says Winston. In 1993, for e...ment continues. And who is winning this "modernwar against nature"? Not us, says Winston. "In spite of a vast increase in the amount of pesticide used o...Free Radicals Implicated In Impaired Lung Function; Damage May Be Mitigated By Certain Antioxidants
...nd levels of several compounds thought to protect against oxidative stress: red-cell glutathione, glutathione peroxidase, trolox equivalent antioxidant capacity and total serum bilirubin, the main pigment found in bile. Schunemann said both laboratory and clinical studies have found that bilirubin may fu...Harbor Branch Oceanographic Institution Receives $1.1 Million Grant From National Cancer Institute
...ling tumor cells which have developed "resistance" against Taxol treatment. Discodermolide has not, as yet, best tested in human beings for the treatment of cancer; those studies not being anticipated for at least another five years. However, the objectives of the Harbor Branch grant will be used to evaluat...