Study At UNC-CH Shows Chlorinated Water Dramatically Cuts Strawberry Contamination
...to be expanded to determinechlorination efficiency against other disease-causing organisms like Salmonellabacteria and other viruses and to other types of produce such as tomatoes andapples," he said. The Clorox Co. and Ramsey-SIAS, an agricultural processing company,supported the UNC-CH research in ...Major Risk Factor For Cervical Cancer Found
... P53 is a key control point in the body's defence against tumour formation. Itprotects the genetic information in the cells from things which can damage themsuch as ultra violet radiation or certain chemicals. If p53 goes wrong then acell has a greater chance of becoming cancerous. Dr Alan Storey, leade...UB Researcher Developing Method That Employs "Evolution" To Identify New Drug Leads
..., which then are screened individually for potency against specific disease molecules. "In combinatorial chem...scientists are using it to develop drug candidates against the enzyme pepsin, which is found in the stomach and involved in the formation of ulcers....Toxic Protein That Interferes With Brain Signals May Trigger Onset Of Alzheimer's Disease
...ADDL binding sitesalso afforded neurons protection against the toxic effects of ADDLs. Finch said the group's results are significant because: "Dogma holdsthat fibrils cause Alzheimer's disease. But we have found that even withoutfibrils, there can be devastating consequences for nerve cells," he sa...University Of Pittsburgh Scientist Discovers How A Novel Vitamin K Stops Cancer Cell Growth
...f we are to maximize the use ofvitamin K compounds against cancer," noted Brian Carr, M.D., Ph.D., FRCP,profe...oducing toxicity. We now aretesting this compound against cancers in rats, and given positive results, wehope to begin clinical trials of this agent within tw...Research Uncovers A Key To Aging And Lifespan Determination
...h has identified a critical weakness in thedefence against aging. Using the fruit fly as a model biological s...y inserting a human gene which is known to protect against oxidativedamage. As a result, the average lifespan of the flies (usually about 80 days)was increased...Colorado State Research Indicates Two TB Vaccines Show Promise
...s tested at Colorado State give long-term survival against virulent infection that would normally kill animals in a few weeks," Orme said. "Both also prevent tissue destruction and actual disintegration of lung tissues seen in people with active TB." While not at present as effective as BCG in animal models...Vaccine Kills Spreading Cancer In Animal Model
...lls but no vaccinedeveloped tumors. A second test against established lung cancer showed that thevaccine com.... To test whether the vaccine is effective against metastatic cervicalcancer, Ji and her colleagues developed a line of tumor cells by geneticallyalter...New Tests Demonstrate MuchLarger, More Specific Immune Responses To Viruses
...T cells, which provide thefront line of protection against invading viruses, is considerably larger andmuch more targeted to specific viral antigens than scientists previouslybelieved. Although it is well known that T cells multiply in the body in responseto viral infection, it has been difficult to ...Scientists Identify Molecular Target For Tuberculosis Drug Treatment
... havethe perfect new tool for developing new drugs against TB." The research was a collaborative project of Dr. Barry's team and NIAID granteeJames M. Musser, M.D., Ph.D., and colleagues at the Baylor College of Medicinein Houston, Texas. Their report appears in the June 5, 1998, issue of Science. Although ...Newly Recognized Cell-Surface Receptor Protects Heart Tissue Against Damage
...tricle cells exert a powerful,sustained protection against injury during exposure to ischemia. "Consequently,...r exposure ofheart cells to ischemia protects them against subsequent damage. Thispre-conditioning is again triggered by adenosine, which ultimately causeschan......monstrated by blocking experiments with antibodies against the p75 neurotrophin receptor, this specific receptor molecule is involved in down-regulating the MHC class II loci. Further experiments confirmed that at least NGF, but to a lesser degree also NT-3, can directly inhibit ...A New Molecular Marker For Prostate Cancer
...tumor growth. As part of the body's naturaldefense against cancer, the p27 protein is found in virtually all normal cells.In previous studies, low levels of p27 protein in tumor cells have been shown topredict disease progression in breast and colon cancer. Researchers divided the 96 tumors into three group...Crystal Structure Of Key HIV Protein Reveals New Treatment Targets
...t unlocks new doors to devising drugs and vaccines against HIV,scientists have crystallized the core of gp120...that a largepart of the gp120 surface is protected against attack by a dense array ofcarbohydrates and by an amazing capacity to change shape," says Dr. Sodros...Peptic Ulcers: Stress Does Matter, After All
...espite the great advances medical science has made against the disease - including treatment for H.pylori - many people still live with its symptoms. "Stress has an influence on the development of ulcers," adds Levenstein, "but it also strongly influences how well you do under treatment once you have an ul......ve "biologicalwarfare" capabilities for protection against stresses. Plants are mostvulnerable in the "root ...t contain novel antibiotics, potentially effective against thedrug-resistant bacterial strains that are currently emerging. When we expose asimilar set of pla...UF Researcher's Innovative Fence Helps Control Sand Flies
... Day hopes to use the sand flies' thirst for blood against them. Betweenthe marsh and the playground he has b...a. Day said many control strategieshave been tried against sand flies, also known as no-see-ums and wingedteeth, but all have failed because of the insects' co...Gene Variant Found That Can Help Protect Against Nicotine Addiction
...hus, those with a null allele had been "protected" against nicotine addictioncompared with individuals with the normal or wild type alleles. In addition,among a group of people who do smoke regularly, those with null CYP2A6 allelessmoked fewer cigarettes over the course of a week than those with normal CYP2A...New Microbial Insecticide As Potent As Bt
...de. The toxins produced by Photorhabdus are active against a wide range of insectsand are at least as potent as the insect-killing poisons produced by Bacillusthuringiensis or Bt, the reigning king of natural insecticides, according toRichard ffrench-Constant, aUW-Madison professor of toxicology in the depar...Discovery Of Plant-Like Metabolic Pathway In Common Parasites Supplies New Targets For Therapy
... infections with Toxoplasma gondii . Similar tests against related parasites areplanned. "We urgently need ne...te growth andsurvival. Glyphosate proved effective against malaria strains that wereresistant to an anti-malarial medicine, pyrimethamine, which interrupts fol...