Adaptive changes in the genome may provide insight into the genetics of complex disease
...TRPV6 and has been implicated in thedevelopment or aggressiveness of prostate cancer. It and another gene in theregion, TRPV5, are also involved in calcium absorption in the kidney,intestine and placenta. Scientists had previously found that geneticvariation in a gene promoting lactose-tolerance in milk drinking Eu...Alterations in vitamin D receptor gene increase prostate, breast cancer risk
...DR variants also contributes to increased risk and aggressiveness of prostate cancer in African-American men, according to the Cancer Epidemiology, Biomarkers & Prevention article. This study reported that men with two copies of the F variant almost doubled the risk for prostate cancer developing in African-Americ...Ants protect plants better when jacked up on nectar
... on the team's findings, "Contrasting the diet and aggressiveness of the ant bodyguards tending an extrafloral nectary-bearing plant," will be given at 10:10 a.m. on Wednesday, Aug. 4, in Room D135 of the Oregon Convention Center in Portland, Ore., at the annual meeting of the Ecological Society of America. Ecologi...Gene expression patterns may help predict risk and progression of prostate cancer
...e model using GeneSpringTM software to predict the aggressiveness of the disease and found that the expression profi...as more than 80 percent accurate in predicting the aggressiveness of the disease. "Since only a fraction of prostate cancers are metastatic, identifying vari...Expression of Rb2/p130 and VEGF could serve as potential liver cancer prognosticators
... independent prognostic markers in determining the aggressiveness of the cancer, according to researchers at the Sba...tic markers because they are going to indicate the aggressiveness of the cancer," says Claudio. "Using these two biomarkers together could be a more universal way to ...Rb2 expression could play vital role in ovarian cancer Temple University researchers find
...d or lost, there was an inverse correlation to the aggressiveness of the cancer," says Giuseppina D'Andrilli, Ph.D.,... protein is still present in the tumor tissue, the aggressiveness of the tumor is less." The researchers then used a viral delivery system to introduce correct copie...New study confirms conservation surgery is safe for BRCA breast cancers
...do not respond to hormone treatment. "Despite the aggressiveness of these types of tumours we found after almost nine years of follow-up that there was no significant difference in recurrence between the BRCA carriers and the non-carriers with a family history or between the BRCA carriers and those with no family ...Social behavior among monkeys may be more nature than nurture
... such characteristics as sociability and impulsive aggressiveness among humans may have a genetic basis, said Dario Maestripieri, Associate Professor in Human Development at the University. The work with monkeys may help other researchers understand the biological origins of characteristics that promote socializati...Steroid use causes long-term agression, NU report indicates
...d doses of anabolic steroids and then measured for aggressiveness over certain periods of time. The researchers init...l consequences. What we know at this point is that aggressiveness doesn't simply cease after the ingestion of steroids does." Based on this research, Melloni also be...Temple study identifies molecular mechanisms that may assist gene in blocking lung cancer
...nverse relationship between Rb2 expression and the aggressiveness of lung cancer. Giordano discovered the Rb2 gene while working at Temple's Fels Cancer Institute in the early 1990s. In those earlier studies, correct copies of Rb2 were introduced into mice with lung tumors using a viral system developed by Pier Pa...Symposium on how 'nature and nurture' impact child development
...sychological" traits such as shyness, fearfulness, aggressiveness and impulsiveness, and that specific neurobiologic substrates (i.e., receptors, and mRNA levels) correlate with these traits. There is evidence, however, for "behavioral transmission" of traits as well. The type of maternal care offspring receive, ap...Genetic fingerprinting improves diagnosis and treatment of sarcoma
...rch for genetic markers thatmay help determine the aggressiveness of tumors and theirpotential response to treatment. In fact, Sloan-Ketteringhouses the largest dedicated database for soft-tissuesarcoma of any single institution anywhere. As Dr. Maki notes, "The knowledge we have gained from thisdatabase has allow...Aggressive tumor cells leave a trail in their environment that affects the spread of cancer
...rs of the MMP family of proteins contribute to the aggressiveness of cancer cells. MMPs are important in helping tumor cells leave a primary tumor and move into and out of the bodys blood (and lymph) vessels. After entering these vessels, tumor cells can travel to distant parts of the body and begin growing in new ...Untangling the matrix of risk factors for alcoholism
...d in antisocial alcoholics who exhibit BD, such as aggressiveness and difficulty controlling alcohol consumption. T...ction and behavioral disorders such as alcoholism, aggressiveness and depression, researchers wanted to further examine genetic variations in the serotonin transporte...A neurogenetic approach to alcoholism
...predictors of subsequent alcohol intake, impulsive aggressiveness and increased tolerance to the side effects of alcohol intake." Heinz said the animals acted more aggressively because they were, in fact, more socially incompetent and felt threatened by social interactions. He speculated that the primates liked t...Studies at UNC plumb tumor resistance to treatment
... in tumor physiology factors associated with tumor aggressiveness and treatment resistance. Among the factors studi...ch tumor and tested for hypoxia and the factors in aggressiveness and treatment resistance. "So we looked at our biopsy samples, looked at hypoxia and looked at ma...Three areas on chromosomes contain prostate cancer aggressive genes
...ers have taken a direct measure of prostate cancer aggressiveness in a genome-wide scan. The results, which appear i...disease," he said. The researchers ranked cancer aggressiveness with the Gleason score, a key pathological measure assigned to a prostate tumor. Gleason score refle...Brain compound's anti-aggression effects appear to reverse in monogamous male rodents
...cation on femalemice. Instead of gaining increased aggressiveness like the males, the femaleslost their aggressive behavior in the one context where it normally showed up,when they were nursing pups and a strange male mouse came around, putting thepups in danger of an attack. For the new study, scientists switched...Antbird capable of increasing testosterone level when threatened
...s when necessary in the "off-season"to boost their aggressiveness against invaders. A team of researchers, led by Ma...ression in natural systems to reallyunderstand how aggressiveness is regulated in humans, and what kinds ofphysiological parameters are important. We know from this s...Genetically-Altered Crops Can Produce Tough, Hard-To-Kill Weeds
...ansgene ofthe crop parent and still hang on to the aggressiveness of the weed parent. These studies picked up speed when transgenic, herbicide-resistantoilseed rape hit the commercial U.S. market in 1993. Since then, oilseed rapeproduction has been on the rise. In 1997, American farmers produced six times...