Award winning researchers reveal potential new role for Glivec
...ted to supporting worldwide translational research aimed at individualising therapeutics. The award is being presented today to Dr. McArthur, the lead researcher, by Professor Esteban Cvitkovic, president of the foundation's scientific board. Dr McArthur, who is head of the Molecular Oncology and Translat...Northeastern University receives $12.4 million NSF grant for creation of nanomanufacturing institute
... develop tools and process to mass-produce devices aimed at fulfilling the promise of nanotechnology on a larger scale, a key component in advancing the technology. The center will accomplish this through high-rate/high-volume guided self-assembly of nanoelements, accelerating the creation of highly antici...UAF scientists discover new marine habitat in Alaska
...hs, Riosmena-Rodriguez conducted a number of tests aimed at identifying the rhodoliths at his laboratory at the Marine Botany Program at Autonomous University of Baja California Sur in La Paz, Mexico. Some of the tests involved slicing the specimens into thin sections and comparing their structure and repr...Environmental decontamination, greenhouse gases, and the genome of a methane-loving bacterium
...y've also been the focus of bioremediation efforts aimed at environmental decontamination. And now, with the publication of the first complete genome sequence of a methanotroph, such efforts will be all the easier. This week in PLoS Biology, a multidisciplinary team spanning the fields of genomics, bioinfo...Key stimulator of colorectal cancer identified
...entifies potential targets for future therapeutics aimed at the prevention and treatment of cancer of the colon and rectum. Colorectal cancer (CRC) is the second most common cause of death due to cancer for men and women in the United States It has been known for some time that NSAIDS and other cyclooxygen...Genetic modification of linseed produces healthier omega 3 and 6 fatty acids
...rable PUFA, pointing the way to future experiments aimed at making improvements in the levels of accumulation and specific profiles of very long chain PUFAs in genetically modified oilseed crops. In addition to the possibility of providing healthier, more nutritious oils for human consumption, this work wi...Byproduct of water-disinfection process found to be highly toxic
...ater Association for a delay of EPA's Stage 2 rule aimed at reducing the amount of previously identified toxic DBPs occurring in chlorine-treated water. "The iodoacids may be the most toxic family of DBPs to date," Plewa said in an interview. One of the five detailed in the study, iodoacetic acid, is...Origin and Development of the Vertebrate Traits
...ects of developmental biology and regeneration and aimed at promoting the free and timely exchange of research achievements. The first annual CDB Symposium, which addressed the "The Origin and Formation of Multicellular Systems," was convened in March 2003, followed by the second annual symposium, on "Deve...Optimizing protein's 'death domain' halts leukemia in laboratory study
...3 subunit from the protein and use it as a sharply aimed tool to shut down the BCL-2 protein and activate the death pathway in cancer cells, without harming normal cells. If that proved successful, it would show that the BH3 alpha helix and alpha helices from many other proteins could be used like keys t...Molecular staples shape a cancer killer
...cience. Korsmeyer, Walensky, and their colleagues aimed to construct a key regulatory segment of an apoptosis-triggering protein called BID that could induce apoptosis in cancer cells. Their objective was to create a short peptide that functionally mimicked the specific region of the BID protein that elic...Analysis fingers causes of desertification
...ication largely respond to national-scale policies aimed at promoting advanced land-use technologies and creating new economic opportunities. ...Diabodies act as guided missiles targeted to mammary tumor growth
... Ongoing studies by Adams and his colleagues are aimed at determining refinements in the radioisotope-bearing diabody that will optimize tumor growth inhibition or reduce tumor mass while preserving the health and function of kidneys. ...New imaging technology at Joslin shown to detect early signs of type 1 diabetes
...nd after experimental or therapeutic interventions aimed at stopping its progression. Further, they point out that the technique already has been used safely and effectively by the MGH group in human clinical trials to detect the spread of prostate cancer to the lymph nodes. "Given the known safety of mag...APS awards more than $140,000 to minority students of physiology
...uranium elicits these responses. "This program has aimed to make careers in physiology accessible to minority students since the 60's and has been widely successful in that goal," said Dr. Martin Frank, executive director of the APS. "Former Porter fellows include a director of a NIH Institute, leaders wi...OHSU-VAMC study sheds light on estrogen's benefit for MS
... to rest when they conducted the first large study aimed at assessing pregnancy and delivery on the course of the disease. The group found there was a marked reduction in the rate of MS relapse during pregnancy, especially in the third trimester. Three years later, Offner and a team of OHSU and Portland VA...Study suggests cell-cycle triggers might be cancer drug targets
...ells don't, making them vulnerable to future drugs aimed at D-cyclins, or their partners, the CDK kinases. In the Cell report, the researchers say they attempted to induce cancer in cells taken from embryos lacking the cyclins, and they remained stubbornly normal. By contrast, cells that contained the cycl...Gene changes linked to increased eye pressure may have implications for glaucoma therapy
... achieved this pressure regulation. This study was aimed at measuring what genes were turned on or off in the TM after the pressure was increased, Borrs added. The UNC scientists knew that the homeostatic mechanism would involve sensing and triggering other genes. They were not surprised that most of t...Rutgers-Newark scientist: Mosquitoes may carry lethal parasite
...h by Cali and one of her graduate students will be aimed at identifying how prevalent B. algerae is in mosquitoes in New Jersey through the collection and examination of specimens across the state. "Microsporidia kill people because they stay below the radar," Cali observed. Studies spearheaded by Cali hav...Bad news for pathogenic bacteria: Scientists find protein essential for bacterial survival
...e to harmful bacteria. "Conventional antibiotics aimed at killing bacteria also put immense pressure on bacteria to survive, and to ultimately develop resistance to these drugs," Artsimovitch said. "Forcing harmful bacteria into a stationary state by controlling ppGpp levels may be the way to circumvent ...Transcriptional gene silencing in nucleus shown by UCSD/VA medical researchers
...que provides a new tool for research investigation aimed at elucidating the effects of different genes, and has the potential to modify gene expression in disease, such as knocking out expression of genes required for tumor growth. He cautioned, however, that further studies are needed to prove the general...