Tag: "alteration" at biology news

Changing Continental Runoff Patterns Could Change Ocean Circulation

Denver, Colo. -- Human alteration of major waterways may cause more problems than drought downstream, according to a Penn State geologist who is studying circulation models of the ancient oceans. "We have already seen some of the consequences of changing surface waterways," sa...

Pinpoint Gene Control Holds Promise For Nervous System Studies

...ften as theirnormal counterparts. The genetic alteration also leads to a greater than 10-foldincrease in the amount of NGF in the hippocampus, the region ofthe brain where scientists inject the virus. The team hasdetected these elevated levels for as long as they've run theirexperiments -- one year. Brooks...

Subtle Biotic Changes Have Big Environmental Impact

... what extent could fertilization of the oceans and alteration of oceanic food webs affect global carbon cycles? In fact, runoff from land is now enriching coastal oceans to unprecedented levels, and industrial fishing is causing massive changes in marine food webs. So the global experiment is underway," s...

Bowman Gray Scientists Find Novel Way To Block AIDS Virus

...rom ever reaching the cell surface. The key is the alteration ofwhat is known as the SDF-intrakine, which binds to the CXCR4 and traps themolecules inside the lymphocyte. Hence there is no place on which the HIV-1 virus can land to infect thecell. "The genetically modified lymphocytes are immun...

UMass Researchers Announce Birth Of Genetically Modified Cloned Calves

... sounds: only one in a million cells have the gene alteration that the scientists hope to produce. These select cells are then grown in a petri dish and fused to cow eggs in which the original genetic material has been removed. The resulting embryos are implanted in surrogate mothers. The resulting offspring, a...

Memorial Sloan-Kettering Investigators

...gene calledBCL-6 make up the most frequent genetic alteration in non-Hodgkin's lymphoma.Alterations in BCL-6 -- which belongs to the same family of genes as PLZF -- turnon this transcription repressor, leading to lymphoma. "We plan to take our newfindings with APL and apply them to design transcription therapy ...

New Gene Alteration Find Points To Aggressive Leukemia Treatment

...mall part of the ALL1 gene. Patientswho have this alteration fall out of remission three times faster than thosewho don’t and their survival is slightly more than half that of patientswho don’t have the defect. The scientists reported their discovery in the journal Cancer Research . The ...

American Museum Of Natural History Holds Symposium On Biodiversity And Human Health Issues

...ctious Disease The causal link between ecosystem alteration and degradation and the emergenceand spread of malaria, human immunodeficiency virus (HIV), hantavirus,hemorrhagic fevers, and Lyme disease. Speakers include: (Overview) Paul R. Epstein, Harvard School of Public Health Richard S. Ostfeld, Insti...

"A Little Bit Here" And "A Little Bit There" Can Add Up To A Big Problem

...er-review process. Previous issues concerned human alteration of the global nitrogen cycle andecosystem services. Look for upcoming issues to cover biodiversity andecosystem function, ecological principals for land use management, andalternative forestry management practices. The Editorial Board members are: ...

USGS And Arizona Game And Fish Begin Partnership To Study Western Yellow-Billed Cuckoo

...hat the two major factors in the bird'sdecline are alteration and destruction of the bird's habitat and pesticideuse in both Latin America and the United States. As is true with otherneotropical species, pesticide use not only can directly cause the death ofthese birds but also can cause population declines due...

Defects In Embryonic Development In Lunatic Fringe Knockout Mice

...signalingmediated by these Delta homologs leads to alteration in the positioning of thesomite boundaries and allocation of cells. "These results demonstrate that Lunatic fringe encodes an essentialcomponent of the Notch signaling pathway in mice and is required for propersegmentation of mammalian embryo...

Focus On The Bay: Pfiesteria And The Chesapeake Bay Ecosystem -- Symposia At Annual Meeting To Examine Science Policy On Pfiesteria And The Bay

...ploration. Introduction of non-indigenous species, alteration of fish and shrimp habitat,and inputs of nutrients are the other "Chesapeake Bay Ecosystem" symposiumtopics. On non-indigenous species, Gregory M. Ruiz, of the Smithsonian EnvironmentalResearch Center, states, "...it is clear that [Non-Indigenous Spe...

USGS To Present Diverse Research At ESA Annual Meeting

...igating other questions about effects of landscape alteration onvertebrate population issues. ("Effects of Habitat Fragmentation on Dynamics of Meadow Vole Populations: AField Experiment," by James D. Nichols, R.L. Hinz, and J.E. Hines, USGS, Laurel,Md., Mon., Aug. 3, 8:15 a.m.)...

UCSF Finding Offers Insight Into Way Genes Regulate Aging And Life Span

... variety of cell subtypes and observed whether the alteration prompted acorresponding change in the mutated cells themselves or in other cells instead. What they discovered was that there was not a one-to-one correspondence,or cell "autonomous" relationship, between daf-2 activity and a cell's behavior...

Oxygen-Carrying Myoglobin Not Necessary For Survival

...handle the different conditions. The only alteration researchers found in the rodents lacking myoglobinwas that the heart and endurance muscles were nonpigmented or almost whiterather than a rich pink because most of the red color actually comes from themyoglobin. "Our research suggests that th...

Hopkins Researchers Find Genetic Colon Cancer Change In Healthy Cells

... Johns Hopkins scientists have found a genetic alteration associatedwith common forms of colon cancer in pat... "It's the first cancer-related genetic alteration found at highfrequency in healthy people," says Andrew P. Feinberg, M.D., who with HengmiCui, Ph.D.,...

Jefferson Scientists Use Gene Repair Technique To Change Albino Mice Cells To Black

...al fellow VitaliAlexeev, Ph.D., corrected a single alteration in the gene that controls skincolor in albino mice cells. The alteration, known as a 'point mutation,' was inthe gene for a key enzyme, tyrosinase. Tyrosinase is involved in making melaninand in pigmentation. By correcting the alteration, tyrosinase ...

Clues To Molecular Cancer Switches Probed

...radation. Therefore, the discovery of a structural alteration in the MMP-1 gene thatinfluences its level of expression is important to our understanding of how thisenzyme modulates extracellular matrix metabolism, " said Brinckerhoff. Thecontinuous production of the enzyme, she adds, could be a factor in tumor...

UD Valentine Science: Cell "Dating" Habits May Promise Healthier Hearts

...kwhether any disease that might be expected for an alteration of the gene islinked to the same region. Most of these adhesive proteins are multi-functional,so I think we'll find that PAM-1 may play a number of roles. By mapping the genein both the human and mouse, we will increase our chances of identifying its...

Wistar Scientists Define Mechanism Of Action Used By Potential Magic Bullet In Cancer Treatment

...d not previously perform. An understanding of RHO alteration as the tumor principle targeted by FTIs willmake it possible to make FTIs more effective, avoid drug resistance problems,and design other types of nontoxic antitumor drugs that target the sameprinciple....

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