Abnormalities in stress hormone response among alcoholics
...serotonin challenge is related to brain damage, or alteration resulting from former consumption of large amounts of alcohol, is not known. An interesting clue, however, is the authors' recognition that the elevated cortisol response is reminiscent of what has been observed in individuals who have never before ...Vitamin deficiency may exacerbate motor neuron disease
...ose target proteins were dimethylated. “That alteration makes the modified protein interact with another p...ith much higher avidity,” Dreyfuss said. The alteration of the arginines quite likely changes the shape of the protein’s surface, making it fit SMN mo......ng away from single gene modifications and towards alteration of several targets within a particular pathway."My own suspicion is that it won't always be this simple," says Apt.On the heels of their success with P. tricornutum , however, the research team is already developing other commercially important micr...Science researchers report 'extremely unstable' gene expression in cloned mice
...ticular gene, called H19, was linked to a chemical alteration in part of the gene called methylation, another epigenetic phenomenon. Methylation, the addition of methyl groups to particular DNA nucleotides, makes the gene harder to transcribe and therefore lowers its expression levels. Degrees of methylation of...How bacteria harden their "armor"
...t negative charge on the bacterial coat. This coat alteration reduces the ability of positively charged antibiotics like polymyxin or certain peptides, to attach to the outer coat -- a key step in the antibiotic's process of piercing the bacterial coat to kill it. According to Raetz, positively charged peptid...Nitrogen: Too much of a good thing?
... in-depth tour of the nitrogen cycle and how human alteration of this cycle is influencing ecosystems worldwide. Experts will address nitrogens role in nature, food production and energy production and use. Representatives of the fertilizer industry will discuss their efforts to meet human dietary needs and p......s forms of estrogen were the culprit in the sexual alteration of fish. He will report his research findings as well as share new statistics on estrogen concentrations in water that were generated by the Canadian Department of Environment in Burlington, Ontario, on Monday, November 5, at the Geological Society o...Answers to Florida bay restoration are clear as mud!
...nal and annual changes in water chemistry prior to alteration of the natural flow of water into Florida Bay. Results of this work are intended to provide target data for restoring seasonal water flow into Florida Bay. For more information on this project Ecosystem History: Florida Bay and the Southwest Coast,...New resources to assist with gene transfer clinical studies
...his allows the correction of a genetic disorder or alteration of the properties of the cell. In this manner, gene transfer protocols, using several viral and non-viral vectors, have addressed such diseases as cystic fibrosis, severe combined immune deficiencies, hemophilia, cancer, heart disease, and AIDS. "Whi......an Medical Association. "This is the first genetic alteration characterized for early-onset Alzheimer's disease ...red cells containing the mutated gene revealed the alteration causes an increase in the expression of the toxic form of beta amyloid, a substance usually found in...Illuminating how plants adapt to light
...called LM-2, resembled a laboratory mutant with an alteration in the gene for the light-sensing molecule phytochrome A. Further analysis showed that the phytochrome A in this strain differed from the normal molecule by only a single amino acid. If this photoreceptor is working properly, excitation by light indu...Genetic takeover threatens crayfish
...ecies like the rusty crayfish represent apermanent alteration to the system," says Perry....December Media Mighlights: GEOLOGY and GSA TODAY
...elf. The dominant bioclasts identifiable after the alteration process are sea lily fragments (crinoids), and it is likely that the broad Palliser platform was characterized by meadows of these filter feeders. The authors conclude that the effects of these destructive processes are often overlooked, and poorly f...Jefferson scientists show how collagen gene mutation leads to osteoarthritis
...Jefferson Medical College have shown how a genetic alteration in a type of collagen can lead to osteoarthritis.The researchers, led by Andrzej Fertala, Ph.D., assistant professor of dermatology at Jefferson Medical College of Thomas Jefferson University in Philadelphia, analyzed a mutation in the gene for a typ...Alcohol consumption during pregnancy alters thyroid function
...lent of the third trimester in sheep results in an alteration of fetal or maternal thyroid function. "The thyroid hormone system plays important roles in growth, development and in the function of other hormone and organ systems," explained Timothy A. Cudd, associate professor of physiology at Texas A&M Univer...The body's production of melatonin may be the reason why the elderly can't get a good night's sleep
...al circadian time. Recent findings suggest that an alteration in the relative timing between the circadian system and the nightly sleep episode may occur with aging and raise the possibility that this altered timing may contribute to the increased sleep disruption with age. The Study To build upon their past re...Hypoglycemia may affect newborn's brain cell function, says Hopkins researcher
.... "Both learning and memory may be affected by any alteration of the ability of the brain to make synapses." McGowan and her collaborators found that low blood sugar levels altered the ability of some neurotransmitter receptors to bind glutamate. These glutamate receptors are known to play an important role in ...A genetic basis for diet-induced relapse of depression
A temporary alteration of serotonin activity can be obtained by acutely and reversibly lowering the blood levels of tryptophan (an amino acid precursor of the synthesis of serotonin). In several studies, acute depletion of trypotphan causes depressive symptoms in some but ...Dietary changes can lower colon cancer risk in families with a history of the disease
...ith a pattern of colon cancer may have some modest alteration in either DNA processing or repair that makes them particularly susceptible to deficiencies in the methylation process. This research may make it possible to identify genes that confer a greater risk of the disease in families with a history of it, F...Researchers have discovered a novel gene alteration that causes an abnormal cellular off-switch that contributes to the growth of colon cancer. Identification of the gene alteration, which appears to contribute to tumor malignancy in about 40 percent of patients with colon cancer, may permit researche...