Study finds that only half of a commonly used cancer drug is activated in cancer patients
...erted into an active form. The implication is that alternative schedules of gemcitabine infusions need to be evaluated carefully." Dr. Parker explained that patients received gemcitabine doses of 650-950 mg/square meter and underwent pharmacokinetic sampling. Mathematical models were developed to calculate the t...Need sex? It's probably something about stress
..., Michod and some of his UA colleagues proposed an alternative explanation called the DNA-repair hypothesis. They suggest that the process which divvies out parental genetic material to sperm and eggs also repairs the DNA that goes into those cells. The repair mechanism keeps the hard knocks that life...OUP launch a new Open Access Journal on Complementary and Alternative Medicine
...or eCAM from the start meant that we could explore alternative funding methods to enable authors not to pay publi... this new, yet ancient, world of complementary and alternative medicine, and will be of particular interest to biologists and biomedical researchers. "CAM has alwa...UF researcher: New low-carb potato to debut in January
...lesh will make this potato an attractive and tasty alternative in many traditional potato recipes," he said. To prepare for what they hope will be a surge in potato consumption by consumers and food processors, Florida potato growers have formed the SunFresh of Florida Marketing Cooperative. ...Molecular marker predicts success of breast cancer treatment
...d to tamoxifen and would therefore benefit from an alternative therapeutic strategy for treatment of early stage breast cancer. According to Dr. Erlander, "This collaboration has us looking at which patients may benefit from tamoxifen and, as a result, many doors of inquiry have been opened." Xiao-Jun Ma, Zunca...Tamoxifen stimulates breast cancer growth following alteration of estrogen receptor
...stant tumors, providing critical time to choose an alternative therapeutic strategy that is more likely to be effective. Because nearly three-quarters of all breast cancers are stimulated by estrogen acting at functional estrogen receptors (ER+), they are most often treated with anti-estrogen compounds ...Umbilical cord blood transplants, bone marrow transplants save lives
...e to find a matching bone marrow donor may have an alternative with umbilical cord blood (CB) transplantation. Loyola's unique method of preparing the umbilical cord blood enables more stem cells to survive, according to Stiff, who also is professor of Medicine and Pathology, Loyola University Chicago Stritch ...Maxygen subsidiary Verdia announces discovery and improvement of glyphosate tolerance gene
...This improvement in enzyme activity may provide an alternative strategy for supporting glyphosate use on major crops such as corn, soybean and cotton. The study, entitled "Discovery and Directed Evolution of a Glyphosate Tolerance Gene," was performed by Verdia under the direction of Linda Castle, Ph.D., Product...ADAM: Good enzyme for Alzheimer disease
..., Germany, now provide evidence that targeting and alternative enzyme, alpha-secretase, might be a useful alternative strategy for reducing AB peptide. In the APP processing pathway, alpha-secretase cleavage of APP ge...JCI table of contents, 17 May 2004
..., Germany, now provide evidence that targeting and alternative enzyme, a-secretase, might be a useful alternative strategy for reducing AB peptide. In the APP processing pathway, alpha-secretase cleavage of APP ge...Bird's eye views earth's magnetic lines
...s suggested in the models by Ritz and Schulten. An alternative suggested by other investigators is that the magnetic field might affect particles of the mineral magnetite, synthesized by living systems, which act like miniature compass needles. The new experiments reported in the May 13 issue of Nature took a...Alternative states in the ocean
...on can be severely abrupt and lead to formation of alternative and potentially persistent states. In the July is...mussels are consumed, or formation of a persistent alternative state if the mussels grow to a sufficient size to escape further predation. The study emphasizes th...Orange, tangerine peels could be better than drugs for lowering cholesterol
...ows promise in animal studies as a potent, natural alternative for lowering LDL cholesterol (bad cholesterol), without the possible side effects, such as liver disease and muscle weakness, of conventional cholesterol-lowering drugs. The findings will be described in the May 12 print issue of the Journal of Agri...Adaptation, niche conservatism, and convergence
... This paper presents the first comparative test of alternative hypotheses to explain these shared features. Did these traits evolve independently in different lineages, in response to the unique Mediterranean-type climate? Alternatively, did the traits evolve first in response to other factors, subsequently prom...Archaeologists announce discoveries at the ancient Maya site of Waka' in northern Guatemala
...he preservation of the park and the development of alternative sources of income for local communities that emphasize conservation of the park's rich natural and cultural resources. "This is an initiative that can position archaeology, not only as scientific research, but as a useful activity for the community...Surprising 'ultra-conserved' regions discovered in human genome
...are transcribed to RNA. Through a process known as alternative splicing, different parts of a gene may be spliced out under different circumstances, so that a single gene can produce several different proteins. Bejerano thinks the association of ultra-conserved elements with alternatively spliced genes is signif...Tropical legume could be alternative hay/forage crop for Texas
...the costs of oil and natural gas, is rising. So an alternative high-protein forage legume such as lablab could ma...is a drier climate. We're interested in finding an alternative seed crop for Texas growers, and drier, less humid climates are more conducive to producing a higher...Soy processing influences estrogen-dependent breast cancer growth in mice
...ietary estrogens to women over age 50 as a natural alternative to hormone replacement therapy (HRT), but this is the age group in which most breast cancers occur. Seventy-five percent of breast cancer cases are diagnosed in women over 50, and the majority of these cases are estrogen-dependent. For these women...Sediments in many Central Valley streams contain toxic levels of pyrethroid pesticides
...sediment-bound, and which are being promoted as an alternative to the increasingly restricted organophosphate insecticides," he said. The study by Weston, Lydy and post-doctoral researcher Jing You in the Department of Zoology at SIU appeared in the April 8 online version of the American Chemical Society's journ...Genetic sequence identified for anti-bacterial sea slug protein
...the marine industry as an environmentally friendly alternative to toxic heavy metals, such as copper, normally applied on materials to prevent biofilm development. Biofilm formation is the precursor to the growth of barnacles and other damaging organisms that must be removed through costly and time-consuming pro...