Other highlights in the February 4 issue of JNCI
... Breast-conserving therapy has been accepted as an alternative to mastectomy in the management of early-stage breast cancer. Because of the increasing interest in PBI--a technique that directs radiation only at the portion of the breast at high risk for recurrence--and in APBI--which has an accelerated schedule ...Molecular level discovery could play role in development of new antibiotics
...c nisin has been used for more than 50 years as an alternative to chemicals in food preservation in more than 40 countries without the development of significant antibiotic resistance. "The use of antibiotics is an important area of medicine, because pathogenic bacteria are always in the environment," van der Do...Inhibition of Borrelia burgdorferi protein may reduce Lyme disease transmission
...e to the tick gut and instead begins expressing an alternative outer surface protein, OspC. In order to determine the function of OspC, Erol Fikrig and colleagues generated a strain of the B. burgdorferi bacterium that was deficient in OspC. These bacteria were able to survive and multiply in feeding ticks; howe...JCI Table of Contents, January 15 2004
...e to the tick gut and instead begins expressing an alternative outer surface protein, OspC. In order to determine the function of OspC, Erol Fikrig and colleagues generated a strain of the B. burgdorferi bacterium that was deficient in OspC. These bacteria were able to survive and multiply in feeding ticks; howe...Waste motor oil management may pose threat to health and the environment
...centive for citizens and policymakers to encourage alternative used oil management strategies, possibly through incentives for treatment and by supporting markets for processed oil products, according to Boughton. But he is quick to point out what he considers the best option of all: use less oil in the first pl...Medical students inadequately prepared for clinical rotations, caring for chronically ill
...in the limits of their illness, ability to discuss alternative information sources and ability to assess equipment needs. Five competencies were included in written materials for a majority of courses: screening for abuse; diagnosing drug addiction, dependence and tolerance; management of dementia/cognitive im...UF study suggests life on Earth sprang from borax minerals
... Diagnostic tools enabled by Benner's work seeking alternative life forms are used today in the clinic to monitor the load of the viruses that cause AIDS and hepatitis C. The work also complements other research Benner is conducting that focuses on ancient forms of life on Earth. In a September report in Natur...Purdue engineers develop quick, inexpensive method to prototype microchips
...develop. Ladisch and his team have developed an alternative method that uses materials easily acquired by any research laboratory, including glass microscope slides, tweezers, thin glass fibers such as those found in glass wall insulation, and a flexible polymer called PDMS that is available from most scienti...OHSU team discovers compound that lacks estrogen's risks
...dulator (SERM) called STX that shows promise as an alternative to estrogen treatment used by postmenopausal women to relieve symptoms of menopause, such as hot flashes and sleeplessness. Martin J. Kelly, Ph.D., and Oline K. Rnnekleiv, Ph.D., professors of physiology and pharmacology at OHSU, led the team of i...New book explains plants, medicine
...to the authors, as a text for courses developed on alternative medicine. "Since 1977, we've seen an explosion in...ise, nutritional foods, lower fat consumption and alternative medicines to improve our health," said Lewis. "Memory and I thought the time was right for our seco...Armies of fighting fungi protect chocolate trees
...n rainforests, they said, offers a viable economic alternative to clearing the forests for ranching. Field tests of fungi as biological control agents are already underway, said the researchers. The biologists published their findings in the Dec. 23, 2003, issue of the Proceedings of the National Academy of Scie...Science paper: Overharvesting of Brazil nuts leading to fewer trees
...il nut extraction has been promoted as an economic alternative to logging and other destructive economic activities without words of caution," she said. "These findings tell us that Brazil nut economic systems are still much better than other extraction systems in the Amazon, but it is crucial to establish annua...Scientists discover way to streamline analysis of maize genome
...ogether provide a complementary and cost-effective alternative to sequencing the entire genomes of complex plants...also has helped us find a rapid and cost-effective alternative to sequencing the entire genome." ...DFG to establish seven new Clinical Research Units
...over School of Medicine is doing research into how alternative approaches can help to improve the situation of lung patients, for example by obtaining donor organs from animals or using stem-cell based therapies to stop organ rejection. A Clinical Research Unit is being established at the University Clinic Wrzbu...With nature's help, a better vision system for smart weapons
...d size, which boosts the cost, Holloway said. The alternative approach of Holloway's team of engineers and physicists relies on diffractive optics, which uses interference effects to redirect light in different directions rather than bending it. Their vision for the technology merges the developments of a 19th-...Sport hunting hits evolutionary traits in bighorn sheep
... the researchers. Wildlife managers should look at alternative strategies "to minimize further deterioration of the genetic quality of bighorn sheep." A world-class trophy ram is a valuable commodity and hunting permits have been auctioned for hundreds of thousands dollars. One sport hunter paid more th...Breakthroughs lead to better understanding in prevention of transfusion-transmitted infection
...les are confirmed by repeat WNV TMA on an index or alternative sample, as well as a supplemental PCR assay and do...n of WNV RNA by PCR (polymerase chain reaction, an alternative NAT method which rapidly synthesizes large quantities of a given DNA segment) and/or WNV IgM antibod...Fox Chase Cancer Center researcher develops new model for studying prions mad cow disease
...he conversion of a normal cellular protein into an alternative structure that forms threadlike fibers called amyloid fibrils. They accumulate in target tissues, such as brain tissue, where they cause the progressive degeneration of cognitive and motor functions and ultimately prove fatal. Amyloid fibrils form a...Scientists uncover novel role for estrogen in bone marrow
...tion of estradiol and/or a 3b-HSD activator, as an alternative to blood transfusions to increase platelet levels. Conversely, patients with abnormally high platelet counts, who are prone to forming clots and therefore at an increased risk for strokes, heart attacks, or even miscarriage (ie. from placental clots)......archers have made progress in the use of GPR as an alternative for TDR, time domain reflectometers, for determini...ists and practitioners are currently searching for alternative techniques. GPR is certainly one of the most promising methods currently under scrutiny". Of course,...