Tag: "amphetamine" at biology news
Brain's 'master molecule' produces same behavior in mice from three different psychostimulant drugs
...tated. The behavioral responsively to LSD, PCP and amphetamine
were thereafter compared between these mutant mice and normal mice. It turned out that single mutations in the amino acid sequence of DARPP-32 virtually abolished the behavioral actions of the psychotomimetics. Schizophrenia-like symptoms such as rep...
Drug improves the sense of touch, Science study says
...ed tactile information. The scientists showed that amphetamine
doubled stimulation-induced gains in tactile acuity. In the presence of an alternate drug, an NMDA blocker, the improvements in tactile acuity, or perceptual learning, gained via finger stimulations were lost. Dinse said that related treatments coul...
Study: Adults maintain significant improvement in ADHD with long-term use of amphetamine
...ted long term with an extended-release mixed-salts amphetamine
medication maintained significant symptom improvem...ndicated a once-daily extended-release mixed-salts amphetamine
medication to be effective and well-tolerated for treating adults with ADHD, Weisler said. This medi...
Gene enhances prefrontal function at a price
...on how the variants affect the brain's response to amphetamine
in the May 13, 2003 Proceedings of the National Ac...e neurotransmitter breaks down more slowly. Since amphetamine
boosts dopamine activity in the prefrontal cortex, the researchers predicted that the drug would, in...
Rats depleted of salt become sensitized to amphetamine, show unusual growth of brain cells
...cent papers. One reported that rats sensitized to amphetamine
showed this type of neuron growth. A second found that rats deprived of food seemed to be amphetamine
sensitized. When an animal or person becomes sensitized their behavior changes. With amphetamine, ...
Scientists find alcohol, drugs boost endorphins in key forebrain region
... significantly in response to alcohol, cocaine and amphetamine
drug administration in a key region of the brain that controls addiction, researchers have discovered. The work, conducted in rats, strongly suggests that the same thing occurs in humans, the scientists say. It offers what could be important new clu...
Ritalin may cause long-lasting changes in brain-cell function, UB researchers find
...hose that occur with other stimulant drugs such as amphetamine
and cocaine, said Joan Baizer, Ph.D., UB professor...in other laboratories has shown that high doses of amphetamine
and cocaine switch on certain genes called "immediate early genes" in particular brain cells and tha...
Differences in response to amphetamines found between males and females pre-puberty
...rth, female mice displayed a higher sensitivity to amphetamine
well before the onset of puberty, but also well after the early postnatal determination of hormone regulation. These findings offer a new understanding of male/female differences in brain function and the response to stimuli. The previous liter...
Gene-Altered Mouse May Provide New Insights To Parkinson's Disease, Substance Abuse And Schizophrenia
... cause the temporary "high" perceivedby cocaine or amphetamine
addicts or the permanent and severe delusionsexper...th care problems." Insights into the mechanism of amphetamine
drugs derived from studying the"knockout" mice should yield new strategies for treating amphetaminea...