Endometriosis: Could angiostatic therapy be the new treatment of the future?
...ference that she and her colleagues tested whether angiostatic therapy (therapy that inhibits the development of ...nce and growth of existing lesions. They used four angiostatic compounds: anti-human vascular endothelial growth factor (anti-hVGF), TNP-470, endostatin and angine...Endostatin promising treatments for AIDS-related cancer
...r cells from proliferating. Endostatin is a potent angiostatic drug in addition to preventing blood vessels from forming, it also stops new tumors from developing. In the case of KS, endostatin appears to cut the communication between the tumor cells and two key growth factors VEGF and bFGF both important to ...First results from novel anti-angiogenic drug trial in patients
...d: "Initially we thought that the drug would be an angiostatic agent that stabilises tumours, rather than an angiotoxic agent that actively shrinks tumours. Angiostatic compounds were associated with a low level of response, but angiotoxics are much more promising in inducing responses. We were happily surprised...