Tag: "animal" at biology news
Warren Pharmaceuticals publishes results of preclinical evaluation
...e efficacy of these compounds in a wide variety of animal
models of disease and injury arises because EPO is an endogenous mediator of tissue protection. By separating the bone marrow activating function of EPO from its tissue-protective function, we have been able to target only tissue injury." said Anthon...
Study suggests first molecular target to halt spread of HPV
...ore proteins. The two substances were tested in an animal
model, in which human foreskin was infected with HPV 11, and then grafted onto immunodeficient mice. Five of 11 grafts treated with ASO407 showed eradication of the virus. Of seven small papillomas treated with ASO407 four were negative for the virus...
Asian bird flu became highly pathogenic through continued circulation and gene swapping
...ermit the virus to infect cells and to spread from animal
or from person to person. The study also showed that a specific type of H5N1 called the Z genotype,...
Lack of immune system protein prevents lupus-like condition in mice
... Health have found. If additional studies in other animal
models and humans confirm that SLAM-associated pro...may avoid that risk." Scientists have used several animal
models to study the immunological underpinnings of human lupus, a condition that afflicts approximat...
Human periodontal ligament stem cells isolated for the first time
...nuing to follow up on this promise with additional animal
work." The results are published in the current issue of The Lancet. Shi said scientists have suspected since the 1970s that the periodontal ligament might contain its own unique stem cells. But, for a variety of technical reasons, the search had...
Experiment station researcher looking for missing links in corn
... would vastly improve feeding costs in segments of animal
agriculture by reducing the need of better protein...upplements, Betran said. "Corn is mainly used for animal
feeding in the United States," Betran said. "About 65 percent goes into animal
feed. If you feed pou...
Milk consumption and calcium intake associated with lower colorectal cancer risk
...m intake has been shown to inhibit colon cancer in animal
experiments, these effects have not been seen consistently in human epidemiologic studies. To better assess the relationship between consumption of dairy foods, calcium intake, and colorectal cancer risk, Eunyoung Cho, Sc.D., of Brigham and Women's H...
UNC research accelerates discovery of novel gene function
... technique can be used in both cell culture and in animal
models to screen thousands of genes for a particul...g, taking gene candidates from cell culture to the animal
model." The technique uses a genetically engineered HIV-1 virus, in which genes can be shuttled amon...
New compound 'highly efficacious' at reducing human tumour growth
...he blood supply of human tumour xenografts. "These animal
data are very promising in terms of anti-tumour efficacy and tolerability", said Dr. Siemeister. "VEGF-RTK inhibitors have been shown to be well-tolerated by patients and we hope that ZK-CDK will be well tolerated. The CDK inhibiting mechanism of ZK-...
Climate may play role in lynx's hunting ability
...was able to track the type of snow and whether the animal
was successful in the kill or not. "This lynx-hare cycle is an amazing phenomenon and it has proven to be a very robust relationship," said Boutin. "If we start to get climate warming and a crusting of the snow without long, deep cold spells, it coul...
Combination of gene therapy and gene silencing prevents neurodegenerative disease
... in tissue culture, but translating those ideas to animal
models of disease has been a barrier. We seem to h...ic to normal brain cells. In the UI study, neither animal
behavior nor brain structures were adversely affected by RNA interference gene therapy. Furthermore,...
As humans alter land, infectious diseases follow
...s, and posing an ever-increasing risk to human and animal
health. Writing this month (July 2004) in the jour... microorganisms, and the health of human, domestic animal
and wildlife populations," according to the report compiled by the Working Group on Land Use Change ...
Gene alteration points to longevity, thinness
...sed activity of the Indy transporter seems to make animal
models at least live longer, healthier lives. The ... function of this single gene is knocked down, the animal
can extend its lifespan." University of Connecticut researchers were the first to recognize the rela...
Donaghue Women's Health Investigator Program awards grants to three at Yale
...by conducting a series of integrated studies in an animal
model of PPD. The findings of these studies will be used for expanding research approaches to PPD and for developing novel treatment strategies. Proctor will generate pilot data on 20 women with hereditary hemorrhagic telangiectasia (HHT), also kno...
In the obese, metabolic adaptations post-weight loss lead to regaining of shed pounds
...ications in exercise and eating habits. Now a new animal
study reveals that when loss occurs, metabolic adaptations occur that mandate a return of the undesired pounds. Background These findings address a key question of whether regaining loss weight due to dieting is caused by metabolic or behavioral ...
Early dexamethasone exposure has long-term neurodevelopment, neuroendocrine effects
...y for chronic lung disease. This is in contrast to animal
models that use short courses or single doses of dexamethasone. Using a within-litter design, 12 pups were assigned to one of three groups on postnatal day 2 (P2). The groups were designated either "handled controls," "saline-injected controls," or ...
The first domesticated donkey was born in Africa
...studies to approach new evidence on the origins of animal
domestication. Other participants in the research were: Albano Beja-Pereira, of the University of Porto (Portugal), who was the study director; Phillip R. England, Pierre Taberlet and Gordon Luikar, of the Joseph Fourier University in Grenoble (Fran...
Measuring blood sugar with a wave of the arm
... he expects that the system could go straight into animal
testing after a minimum of "tweaking." "We've been developing the technology for years now on a real shoestring budget," he says. "If somebody came along and said, 'Let's do it,' it could be a very quick process."...
Purdue yeast makes ethanol from agricultural waste more effectively
...idues that would otherwise be discarded or used as animal
feed, and the first license for the yeast has been issued to the biotechnology company Iogen Corp. Purdue's genetically altered yeast allows about 40 percent more ethanol to be made from sugars derived from agricultural residues, such as corn stalks ...
Mice with hyperactive Wnt10b gene eat all they want, but have half the body fat of normal mice
...d human newborns, which generates heat to keep the animal
warm. While the transgenic mice in the U-M study had half as much white fat as normal mice, they had virtually no brown fat at all. This made it impossible for them to maintain their core body temperature, leaving them very vulnerable to cold. For re...
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