Duke researchers find existing drugs can stop fungus that attacks AIDS patients
... then develop fungal infections. Our findingmay be another step in developing an effective line of defense against thesepotentially deadly pathogens." Once an infection is established, treatment options are limited. Themost effective anti-fungal drug, called fluconazole, requires lifetime therapyin AID...Munching Microbes Make A Meal Out Of Toxic Substances
...g the bioavailability issue becomes important." In another project, Nies is working with the Indiana Department of Transportation to clean up soil contaminated by gasoline that has leaked from underground storage tanks. Newer storage tanks are made to resist corrosion, but the older ones corrode, break open ...First Planned Release Of Captive Lemurs In Madagascar Wilds Expected In Fall
...iest,"they noted in their restocking proposal. And another possible culprit isinbreeding. In general, "black and white ruffed lemurs are among Madagascar'smost endangered," Katz said. "They can only survive in primarytropical rainforests. They cannot adapt to cleared land or secondary forest.They are also a...Enzymes Targeted As Key To Understanding Drug Interactions
...ou go to one doctor for your back problem. You see another for high blood pressure. Perhaps you consult a thi...n between medications? Or when one drug may render another ineffective? News stories have highlighted the problem of pharmacists who failed to question prescri...Low Iron Levels Cause Weakness In Women Who Are Not Anemic
...es, where about 40 percent of women are anemic and another 40 percent are iron-depleted without anemia, low iron stores can have dramatic consequences on a woman's ability to do physical work and make a living," said Haas, who studies the functional consequences of mild to moderate forms of malnutrition worl...Calorie Restriction Reduces Age-Related Muscle Loss
...scles. Weindruch and Aiken's team also focused on another potential playerin the aging process: deletions in the mitochondrial genome, the completeset of genes pertaining to each mitochondrion. Finally, they examinedfibers in specific rat muscles. Researchers examined muscle tissue from old rats on unrestr...Second Look Acquits Gene Of Role In Breast Cancer
"This may just be another something the cancer cell messes up." Johns ...ikely to helpcreate cancer. "This may be just another something the cancer cell messes up," says AndrewFeinberg,M.D. "It definitely does not appear to be...First Salmonella Vaccine For Poultry To Be On The Market Soon
... vaccine as a carrier to immunize chickens against another profit-robbing disease in poultry, Escherichia coli (E. coli). This vaccine has been designed and constructed by Megan Health Inc. scientist Kenneth Roland using some recombinant salmonella clones from the Curtiss laboratory. This vaccine presents ...Second Gene Responsible For Tuberous Sclerosis Complex Identified
... his orher children, who will then have TSC. Like another neurogenetic disorder calledneurofibromatosis, TSC...ation seen in the TSC1 generesembles those seen in another tumor suppressor gene called p53 which has beenlinked to apoptosis, or programmed cell death, and ha...New Gene May Intensify Breast Cancer Growth
...tors, ultimately enhancing tumor cellgrowth. "It's another example where information that we have about other members of thisgene family allows us to infer that this may be very important in breastbiology, regulating not just steroid growth response but possibly other growthresponse pathways. It could eventu......ndGurdyal Besra discovered the set of proteins has another face. Antigen 85 alsoplays a key role in protecting the tuberculosis bacteria from drugs, anunexpected finding that can help develop new treatments that specificallyinhibit this function. "When we confirmed what we had, we were shocked," Bel...More To Drought Than Meets The Eye
...sizing. The researchers decided to look at another measure of a tree's droughtresponse, the amount of energy put into trunk growth. "It appears that the drought tolerance ranking of trees in CentralPennsylvania based on ecological distribution or leaf physiology during droughtis not an indic...Oaks' Defenses Help Gypsy Moth Caterpillar Fend Off Virus
...ar pulp paperindustry. "However, there is another threat, the Asian gypsy moth, which eatsconifers and has been introduced at several seaports by ships from the FarEast," says Appel. "But so far, these introductions have been eradicated." While gypsy moth mothers do not fly, the Asian gypsy...A New Biochemical Link Established Between Stress, Sex And Dominance
...t remarkably, if a territorial fish is defeated by another territorial male and loses his status, he loses the symbols of status as well. The colors and eyepatch fade, the GnRH cells in the brain shrink and so do the gonads. "In our lab, we have shown that behavior influences the brain," said Fernald. "We'v...Experts: Public Will Accept Irradiation In Wake Of Meat Recall
... Americans that it's time to accept irradiation as another technique to safeguard their food supply, two Purdue experts say. Irradiation is little used and a lot misunderstood, but it can destroy the microorganisms responsible for food-borne illnesses and extend the shelf life of perishable foods. It is an...One Chimp Can Perceive States Of Awareness In Others
...r the test was whether onechimpanzee could tell if another was ignorant of a specific situation, inthis case,...od since no chimpanzeeis going to willingly inform another about the presence of food that theythemselves don't have access to," she said. But when the g...Maternal Lead Exposure Linked To High Numbers Of Cavities
...eeth and salivary glands. The scientistsdiscovered another possibility: They found that pups of exposedrats produced 30 percent less saliva, which protects teethagainst cavities by neutralizing acids, providing minerals, andin many other ways. In addition, they detected levels of lead inthe mothers' milk tha...MGH-Led Team Finds Gene For Crippling Neurologic Disorder
... an environmental stress, infection or a change in another gene. If the mutated gene product is set off, there is no stopping it, but if the process does not start by 28, people with the mutation are virtually free from the risk of developing symptoms. We now have an important clue to help us find that tri......n. Dr Topping says resistant starch may soon have another great benefit:researchers are studying ways to use it as a "taxi" to covey otherbeneficial substances into the lower bowel. For example chemicals or even bacteria which help protect against cancerand other diseases could be encased in the resistant ...