Bacteria use 'molecular lasso' to cop copper
...ge of Biological Sciences. Methanobactin may have antibacterial properties, and its ability to absorb copper may f...Spirito at Iowa State University are exploring the antibacterial properties of this compound." Besides Kim, co-authors of the Science paper include DiSpirito and D...Bad news for pathogenic bacteria: Scientists find protein essential for bacterial survival
...ysiological stimuli may help scientists create new antibacterial drugs that target mechanisms specific and unique to harmful bacteria. "Conventional antibiotics aimed at killing bacteria also put immense pressure on bacteria to survive, and to ultimately develop resistance to these drugs," Artsimovitch said. "Fo...... natural organohalogens have potent anticancer and antibacterial activity, and one organochlorine, vancomycin, is the life-saving drug for treating penicillin-resistant bacterial infections in hospital patients. "The first edition in 1996 had about 2,400 compounds," he says. "The new edition will have m...Antimalarial substances found in New Caledonian sponges
...ounds, the phloeodictines, alkaloids with powerful antibacterial properties (2) . Up to now, only deep-water species of Phloeodictyon were thought to synthesize these alkaloids, present in all the samples of such bathyal forms taken from an array of seamounts off the southern sector of New Caledonia. However, phl...Molecule that 'blocks' key bacterial enzyme may lead to new antibiotics
... works sets the stage for the development of novel antibacterial drug designs." To understand how MccJ25 works, Ebright's group used genetic methods to test hundreds of thousands of RNAP derivatives, or variants, in order to define the binding sites for MccJ25 on RNAP. The researchers also used biophysica...Antibiotic resistance risk from triclosan questioned
...sed in the 1990s suggested that the general use of antibacterial products, particularly those using the biocide tri...conducted of homes and clinics were unable to link antibacterial use patterns with changes in resistance."...UNC study finds protein in male reproductive tract kills bacteria, may improve fertility
...covered is an active defensin, one that has potent antibacterial activity," Hall said. In humans, defensins are produced in the skin, eyes, nose, ears, mouth, digestive system, lungs and reproductive tract. "When a pathogen tries to enter our bodies, defensins are ready and waiting there to kill them," Hall said. ...Frog skin and supercomputers lead Penn chemists to designing better bacteria killers
...gned, synthesized, tested, and then improved novel antibacterial compounds, using a combination of laboratory experiments and painstaking simulations on supercomputers. The resulting material could be anchored to the surface of almost any type of product that you would prefer to keep bacteria-free from bandages t...Devastating parasitic weed may be felled by toxin borrowed from flies
...y. But the toxin he decided to experiment with, an antibacterial peptide that is part of the defense arsenal of the...rape be repelled by this souped-up off shoot of an antibacterial peptide from a flesh fly? Yes. But the results are somewhat uneven. In some instances, the broomrap...ASM Biodefense Research Meeting
...earchers in the field of biological warfare Novel antibacterial countermeasures New approaches to vaccine development Use of advanced laser and biochip technologies for biodefense Comprehensive media facilities will be available. The press center will be located in the Baltimore Marriott Waterfront Hotel. Pro...Researchers adapt RNA interference to study gene function on a large scale
...reen could yield key targets for pathogen-specific antibacterial drugs, he said....Bacteriophage genomics approach to antimicrobial drug discovery published in Nature Biotechnology
...y of screening for compounds that address the same antibacterial targets attacked by phages is a very good way of identifying novel compounds against many different bacterial species," concluded Dr Wu. Applying its novel antibiotic discovery platform, PhageTech has identified eight novel antimicrobial targets agai...Tips from the Journals of the American Society for Microbiology
...strain able to invade eggs and survive despite the antibacterial defenses found in egg whites which limit the growt... 7435-7446.) TRICLOSAN: THE NEXT NEW DRUG? The antibacterial compound triclosan, used in dermatological and oral hygiene products as well as antibacterial soaps ...Biofilm antibiotic resistance may be susceptible to genetic approach
... to begin to understand how biofilms can withstand antibacterial treatments. The results of the study, published in the November 20 issue of Nature, provide an innovative model for the investigation of biofilms that may lead to the development of new methods to hamper their resilience. "We are beginning to get at...New class of antibiotics stops pathogens in their genetic tracks
...searchers have found that a promising new class of antibacterial chemicals inhibits one of the most fundamental pro...t- and side-effects," she said. This new series of antibacterial compounds holds great promise for designing drugs specifically targeted to major classes of bacteria...Tips from the Journals of the American Society for Microbiology
...BIOTIC RESISTANCE An ingredient commonly found in antibacterial products does not appear to contribute to antibiot...ed and Environmental Microbiology. Triclosan is an antibacterial compound frequently found in domestic and clinical applications. Although concentration levels are ...Dual action anthrax vaccine more effective
...cine. Research shows it may be important to raise antibacterial antibodies in those individuals to combat bacilli that multiply in victims long after antibiotic treatment has ended. To make the vaccine, the scientists chemically joined two anthrax molecules that are the bacterium's major virulence factors in dise...From studies of a rare human mutation to new approaches to herbicides or antibiotics
...en lead to the development of novel herbicides and antibacterial agents. The report, "Control of Tetrapyrrole Biosy... of PBGS, providing a novel class of herbicides or antibacterial agents useful in areas as far-flung as treatment of patients or prevention of bacterial infection of...Researchers envision intelligent implants
...then provide therapy by dispensing the appropriate antibacterial compound from an internal reservoir and monitor the effectiveness of the treatment. In addition, the implant would be able to communicate what it had done back to a physician using wireless technology. The group, which met for the first time in A...Michigan, Connecticut and Illinois chemists receive award for drug to combat antibiotic resistance
...lid (Zyvox®), is the first of any new class of antibacterial agents to reach market in 35 years. The discovery and development of linezolid was the culmination of more than 12 years of research at Pharmacia and Upjohn. The drug works by preventing bacteria from making the proteins they need to grow and reprodu...