Welch Award honors 2 for unlocking nature's secrets
...ther efforts to mimic nature and produce vitamins, antibiotics and other beneficial products in a shorter time and with less cost in terms of both money and the impact on the environment," said Richard J. V. Johnson, chairman of the board, The Welch Foundation. "The work of Drs. Battersby and Scott truly embodie......, headache, fever and a stiff neck. Treatment with antibiotics in early stages of the disease is effective in most cases. The Lyme disease microbe is extremely difficult to isolate or culture, so most doctors look for evidence of the rash at the site of the tick bite or antibodies to B. burgdorferi in the blood...Unexplained infertility -- the way forward in the fog
...hould follow five escalating steps: a course of antibiotics (tetracycline or doxycycline) for both partners + three attempts at intra-uterine insemination (IUI) + clomiphene citrate (a drug used to stimulation ovulation) + IUI for three cycles* gonadotropins (ovarian stimulatory hormones) + IUI for thr...Fruit fly model could explain how mosquitoes carry malaria: new drugs and vaccines on the horizon
...lasmodium parasite is that it becomes resistant to antibiotics very quickly. "The first drugs used to treat malaria were inexpensive and had few side effects, but they are no longer effective because the parasite has become resistant," Schneider explains. In fact, chloroquine resistance continues to increase i...Antimalarial drug may point way to new class of antibiotics
... the chemicals would represent a new class of antibiotics for the treatment of such prob... to do the same job." The antibiotics from the gentamicin family proved to be the most potent, and for good reason, he......ribosome is a major target for antibiotics. Many antibiotics cure disease by selectively inhibiting the protein...terial diseases that were brought under control by antibiotics in the 1940s and 1950s will once again become scourges. "Now that we know the structure of the lar...More than 300 regularly prescribed medicines can damage the lungs
...the treatment of ventricular arryhthmias. But some antibiotics are well up the list, as are antirheumatics (including methotrexate and several nonsteroidal anti-inflammatories), or ergot derivatives used to improve the brain functions of elderly patients or to treat Parkinsons disease. A recent British study eve...K-State professor develops vaccine to stop liver abscess in cattle
...producers might get to say good-bye to the current antibiotics they use to deter liver abscess in cattle, and hel...ut Nagaraja said there is concern about the use of antibiotics in cattle. "There is increasing concern that the long-term use of antibiotics can lead to developmen...Prions may play crucial role in evolution.
... kind of food they eat, change their resistance to antibiotics and even grow colonies with completely different shapes. In some cases the prion may simply cause the protein production machinery to read through the "stop sign" at the end of a normal gene. This would create a protein whose function is altered by...Sea may be source of future medicines
...tes with bioactive compounds could be screened for antibiotics because they could be cultured in the laboratory, said Hill. "Fifty to sixty percent of a sponge's wet weight is bacteria," he said. "So we had to determining whether the positive results were from the sponge or it's bacteria." The challenge now, h...Antibiotics, yogurt seen as potential treatment for common liver disorder
... true for humans, a daily cup of yogurt or dose of antibiotics may become the first effective treatments for a co... FLD could be relatively easy using yogurt or oral antibiotics to constrain intestinal bacterial overgrowth." Both humans and animals have bacteria in their int......ctually be good news. Bacteria become resistant to antibiotics when the non-resistant members of a colony all die. So they might take longer to develop resistance if growth is merely inhibited. "I think there is much less selective pressure with this type of strategy than with antibiotics," says Howard. How...Zinc supplementation reduces duration of diarrheal episodes in infants in developing countries
...eived by caregivers as a desirable alternative to antibiotics and other drugs. The across-the-board benefits of zinc supplementation suggest that zinc should be provided to all children with acute and persistent diarrhea in settings where it is common. Attention should now be focused on the best means of ......ra, dysentery, and typhoid fever. New vaccines and antibiotics may ultimately result from the research, completed at a time when drug-resistant bacteria are on the rise. Heithoff and colleagues Michael J. Mahan, Robert L. Sinsheimer and David A. Low demonstrated how Salmonella bacteria could be disabled by knock......against typhus in 1948 and became one of the first antibiotics in large-scale production. However, by 1950 it wa...s such as meningitis and typhoid fever where other antibiotics are either ineffective or contraindicated. Limited studies in humans have associated the drug with...Advisory panel on federal report on carcinogens makes recommendations to NIEHS/NTP for new listings
...ve against typhus in 1948, it was one of the first antibiotics in large-scale production but after being linked t...o cases of typhoid fever and meningitis when other antibiotics were ineffective. The scientific panel, a part of the National Toxicology Program Board of Scientif...Scientists uncover break-and-entry strategy of disease-causing bacteria
...rial infections that are now resistant to multiple antibiotics available today," says study leader Michael G. Cap... where they can intervene. "New classes of current antibiotics simply buy us a little time. We have to come up with new ways of thinking about the problem," Caparo...Tipsheet: Journals of the American Society for Microbiology
...rchers tested the effectiveness of eight different antibiotics on 300 enterococcal isolates from the hospital, a third of which were resistant to vancomycin. Only the antibiotic nitrofurantoin was effective against them all. "We conclude that nitrofurantoin may provide effective treatment of urinary tract in...Antibiotics for the next generation
...ntibiotics, Novobiocin and Ciprofloxacin. The two antibiotics produced clearly different gene "signatures" on th...logy will help in classifying and developing novel antibiotics to combat increasingly resistant bacterial strains....Human gut potential breeding ground for antibiotic resistance
...in the human gut. "For example, you feed a pig antibiotics for a large part of its life. The bacteria in the... infections are increasingly becoming resistant to antibiotics commonly used to treat them, such as clindamycin, which is in the same family of antibiotics as eryt...