Tag: "antibodies" at biology news
Cell Genesys reports antitumor activity in Phase I/II GVAX lung cancer vaccine trial
...e as well as the formation of new anti-lung cancer antibodies
in the blood. Update on Initial Trial of GVAX Lung Cancer Vaccine An earlier Phase I/II trial of GVAX lung cancer vaccine in patients with advanced non small-cell lung cancer which was conducted by Dr. Glenn Dranoff and colleagues at Dana-Farber/Part...
ASM journals tipsheet: May 2001
...Ahmed and P.E. Rollin. 2001. Passive transfer of antibodies
protects immunocompetent and immunodeficient mice against lethal Ebola virus infection without complete inhibition of viral replication. Journal of Virology, 75: 4649-4654.) BACTERIAL NASAL SPRAY COULD PREVENT FLU A nasal spray containing bacteri...
Chronic Lyme disease symptoms not helped by intensive antibiotic treatment
...onic Lyme disease patients who tested positive for antibodies
to the Lyme bacterium, while the other trial enrolled 51 people with chronic symptoms but no evidence of antibodies. In each study, volunteers were assigned at random to receive either antibiotic treatment or an inactive placebo. Treatment cons...
Research team unlocks secrets of the firefly flash
...nside the firefly lantern using special stains and antibodies
to see where the NO-producing enzyme might be located. The enzyme was discovered in a strategic location - right next door to the light-generating apparatus in the photocytes. Taken all together, these findings suggest how the flash control machiner...
UK scientists develop 'his-and-hers' fertility test kit
...automatically collected, tagged with gold-labelled antibodies
and detected on a nitro-cellulose strip. If there are adequate numbers of sperm present and if they are sufficiently motile, the test will produce an easy-to-read red line. This appears when the semen sample has greater than 10 million motile sperm p...
Science, engineering and technology news tips
...752-4533, firstname.lastname@example.org . Infinitely sticky antibodies
deliver cancer treatment Using antibodies
as "smart bombs" to carry doses of radiation straight to tumor cells is the aim of research by Unive...
Researchers discover how immune system rids nervous system of mosquito-borne viruses
...encephalitis. Our previous research indicated that antibodies
successfully clear infection from the central nerv...rved mice that did not have the ability to produce antibodies
and compared them to normal mice. The mice were infected with Sindbis virus, a mosquito-borne virus ...
Hendra virus has a growing family tree
...idence such as some bats being found with specific antibodies
to the virus. The relevant State authorities successfully contained outbreaks of the Hendra and Menangle viruses. The Nipah virus outbreak in Malaysia was also successfully brought under control. The Executive Committee of the International Committ...
Harnessing the autoimmune response
...is thought to explain the genesis of self-specific antibodies
in autoimmune disease. Here, Chackerian and cowor...conjugation could be used to generate neutralizing antibodies
to, and provide long-term suppression of, a variety of self or foreign molecules....
Component of fly saliva makes promising Leishmaniasis vaccine
... the parasite. Because sand fly bites produce both antibodies
and T-cell responses, the researchers analyzed the mice to see which type of immune response was keeping the parasites in check. When the NIAID team vaccinated "knockout" mice, genetically engineered not to produce antibodies, the mice were still pr...
Structure solved by scientists at The Scripps Research Institute marks important milestone in effort to develop HIV vaccine
...ody against HIV. Also called immunoglobins, these antibodies
would be produced by the body's B cells after HIV ...e bloodstream. During such an immune response, the antibodies
would circulate through the blood, and track down and kill the virus. Normally, the antibodies
Scientists at the Scripps Research Institute find a way to block prions that cause mad cow disease
...f Immunology at TSRI, originally developed several antibodies
in order to probe the structure and biochemistry of prion proteins and investigate the way in which the binding of infectious prions to the normal prion protein occurs. But one antibody they designed seems to halt the infection all together. This ant...
New epilepsy gene identified in mice
...cuitry properly. The scientists are now developing antibodies
to the MASS1 protein to use in tracing its location and interactions with other proteins. The scientists have also identified the human gene homologous to mass1, said Ptacek. In addition, they are collaborating with other scientists who have identifi...
UC researchers have discovered novel cell adhesion mechanism that may lead to improved treatment for sickle cell disease
... the UC researchers noted that P-selectin blocking antibodies
reduced the stickiness between sickle cells and cells that line blood vessel walls. This demonstrates that P-selectin is specifically involved in sickle cell adhesion, said Matsui. They also noted that sickle cells stick to P-selectin that is attac...
Scientists at The Scripps Research Institute discover a previously unknown role for antibodies
...pps Research Institute (TSRI) have discovered that antibodies
have a novel catalytic abilityunique among protein...of the journal Science, the team demonstrates that antibodies
can catalyze the formation of hydrogen peroxide from singlet oxygen. All antibodies
have the ability...
From embryo to placenta, gene transfer in primates a success
... mothers carrying the engineered embryos developed antibodies
to the jellyfish protein at about mid-pregnancy. Despite this immune response, the pregnancies were carried successfully to term, demonstrating that primate embryos with working transgenes are a viable experimental model for exploring how the materna...
Bizarre new protein blocks a real-life terminator
...to be an evolutionary ancestor of disease-fighting antibodies
in humans. In a study published in the Sept. 14 i...f using the AT protein is comparable to the use of antibodies
- special proteins in people and other vertebrates that bind to and fight off invading molecules and...
Scientists discover how some viruses take strong hold of cells
...dden from the body's immune system, which produces antibodies
to fight infections. "If you think of the virus as a golf ball, the binding sites that recognize the receptor are inside the dimples," Freimuth says. "Antibodies can't fit into the indentations, but the receptor is a slender molecule that can fit in....
Censoring self-specific B cells
...his autoimmune condition. Since VH4-34-containing antibodies
recognize bacterial carbohydrates in addition to t...hat they do not induce chronic autoimmunity, these antibodies
may play a valuable role as a the rapid host response to bacterial infections. Evidently, the abili...
Researchers build diagram of cell cycle clock
... molecular soup of DNA-protein complexes. Specific antibodies
coupled with magnetic beads are then used to fish out DNA fragments cross-linked to the proteins. This provides researchers with a population of DNA-protein complexes, and unhooking the cross-linked DNA from the protein leaves them with DNA fragment...
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