Tag: "antiviral" at biology news
Keep genome data freely accessible
...didates and diagnostic tests, and helped guide the antiviral
drug research. "Unfettered, free access to the results of life-science research . . . has served science and society well", the panel argues, accelerating research and speeding the "life-saving benefits" of that research'. The editorial concludes: 'B...
Cannabis may help combat cancer-causing herpes viruses
...ournal BMC Medicine, could lead to the creation of antiviral
drugs based on nonpsychoactive derivatives of THC....gainst gamma herpes viruses than the commonly used antiviral
drugs acyclovir, gancicyclovir and foscamet, said Dr. Medveczky, a professor in the Department of Me...
First glimpse of DNA binding to viral enzyme
...he enzyme and are already being used to design new antiviral
drugs to block this interaction. "We were quite s...gets for drugs to block the interaction and act as antiviral
agents, Mangel said. The scientists have already begun looking for such drugs and hope to have the N...
Sugar-coated sea urchin eggs could have sweet implications for human fertility
...ty of possible medical uses, as anticoagulants and antiviral
agents, for example. The research was supported by Friday Harbor Labs, the State University of New York at Stony Brook, the National Science Foundation, and the Norwegian and Brazilian research councils....
The future of HIV therapeutics is brightening, according to Gladstone Institutes Director
...e development of a broad spectrum of promising new antiviral
drugs, according to an invited commentary on the t...esearch of naturally occurring factors with potent antiviral
properties is opening the way for future development of an entirely new class of anti-HIV drugs. New...
Study of flu patients reveals virus outsmarting key drug
...anese children with influenza and treated with the antiviral
drug oseltamivir was conducted by an international... even after five days of treatment with the potent antiviral
agent. "The problem with this compound is that a single (genetic) mutation makes the virus resistan...
Bright idea could doom cancer and viruses, say Purdue scientists
... its long chemical name - also has potential as an antiviral
or blood sterilizing agent because it is lethal to any nucleic acid it encounters, including the RNA found in viruses. "Our study also found the rhodium complex capable of rendering the Sindbis virus inert," Morrison said. "Since blood cells and pla...
Colleagues to recognize research leadership in cancer detection, prevention and treatment
...tributions in the fields and encompass anticancer, antiviral
and antifungal agents. Nutrition, cancer and cancer prevention:AACRDeWitt S. Goodman Memorial Lectureship. Supported by anonymous contributions from two AACR members, the award memorializes an international leader in the field of nutrition and canc...
Antimalarial substances found in New Caledonian sponges
...ubstances, some of which possess anticarcinogenic, antiviral
or antiparasitic properties. Only 1% of recorded marine species have had their chemical composition analysed. IRD scientists and their partners (1) have investigated the chemical structure of substances extracted from New Caledonian sponges. They d...
HIV reveals evolution of a primate defense against intragenomic infiltrators
...argets it for degradation, thereby eliminating its antiviral
activity. Since the protein-binding regions that govern these interactions have a direct effect on the fitness of both virus and host, one would expect to see the proteins angling for advantage, with Vif maximizing its ability to recognize APOBEC3G a...
Report outlines steps needed to lessen smallpox threat
...major collaborative research effort to develop new antiviral
drugs that would involve the pharmaceutical and bi...he estimated price tag for developing two or three antiviral
drugs at $1.5-$2.5 billion, it is likely that the government is going to have to consider new ways o...
Asian bird flu became highly pathogenic through continued circulation and gene swapping
...alled M2, known to cause resistance to a family of antiviral
drugs used to treat human influenza. The mutation also developed in some genotype B, Y and Z+ viruses. The fact that the M2 resistance mutation is arising in different viruses suggests that it can be readily acquired, according to the researchers. ...
Small trial shows daclizumab add-on therapy improves MS outcome
...eated with beta interferon - a naturally occurring antiviral
protein commonly used to treat MS. Patients also received 7 treatments of daclizumab (a genetically engineered human antibody that blocks the interleukin-2 receptor on immune cells) administered intravenously at 2-week, and later, 4-week intervals. ...
Tips from the Journals of the American Society for Microbiology
...l Microbiology . "Currently, there are no suitable antiviral
drugs or an effective vaccine for SARS virus. Rapid laboratory confirmation of SARS-CoV infection is therefore important for managing patient care and for preventing nosocomial transmission," say the researchers. In the study, throat and nasal samp...
Jay Levy honored with 2004 Abbott Laboratories Award in Clinical and Diagnostic Immunology
.... Levy went on to discover a novel noncytotoxic antiviral
response in CD8+ cells, where immune cells suppres...ion of CD8+ cells with PDCs or interferon restores antiviral
responses. After graduating with high honors from Wesleyan University, Levy received Fulbright a...
Study: Mimicking viruses may provide new way to defeat them
... growth and reproduction. But, he points out, this antiviral
approach cannot always outsmart the virus: "When a...t strains. "Despite advances in the development of antiviral
therapies over the last decade, the emergence and outgrowth of drug-resistant virus strains remains ...
New RNA libraries can selectively inactivate human genes
... human or mouse cells because there are additional antiviral
responses that recognize double-stranded RNA," sai...he machinery to do RNAi is in mammalian cells, the antiviral
machinery makes the introduced RNA toxic, and the cells die." Researchers subsequently disco...
Ribozyme package effective against hepatitis B virus
...pices of an NIH contract which supports testing of antiviral
reagents. "The treatment effects were quite dramatic," Clawson said. "We recorded a greater than 80 percent reduction in the HBV liver DNA, meaning far less virus was being produced, and staining for the virus using antibodies also showed a dramatic ...
Pioneering flu researcher wins major Imperial scientific award
...ch as HIV, a discovery which has helped to develop antiviral
drugs that interfere with this mechanism. Most recently, Sir John led a team of MRC scientists in mapping the structure of the strain of influenza responsible for the 1918 pandemic, which globally killed more than 20 million people. Researchers at ...
Common virus may contribute to uncommon bone disease in children
...tely shift treatment away from chemotherapy toward antiviral
treatments or approaches that modify the immune system." Much further research is necessary, he added, but in addition to guiding treatment, future research may lead to a simple blood test to diagnose the disease. "Such a test would be less invasive ...
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