Penn State researchers unravel key facts about how a virus exits a host cell
...offer a new target for the development of a single antiviral drug for a wide spectrum of viral diseases such as...this raises the possibility of developing a single antiviral drug for a wide spectrum of viral diseases. This is rather like the idea behind broad-spectrum antib...Progressor chimpanzees could reveal mechanism for resisting AIDS
...rmal, stable numbers of CD4+ T cells, and vigorous antiviral immune responses. Yerkes scientists, however, have identified a compelling contrast between LTNP chimpanzees and LTNP people. LTNP chimpanzees maintain normal numbers of T-cells and levels of immune activation comparable to HIV-negative chimps. Human...NIH scientists unravel clues to ebola hemorrhaging
...have provided a molecular target for potential new antiviral drugs and vaccines," states Dr. Nabel. This study also begins to reveal the basic mechanisms of how Ebola virus attaches to and enters cells, and future studies will continue to investigate how different regions of the virus surface perform differen...Clinical trial will test controlled 'drug holidays' to counter HIV
... that the answer to AIDS will be found in improved antiviral drugs," says Dr. Montaner, principal investigator on the scientific study that led to development of the new trial. "Immunologists like myself, however, see in the drugs an opportunity to use them for eliciting a long-term immune response that ultima...Novel antiviral drug concept targets number of human viruses
In laboratory studies, an entirely new approach to antiviral drug development is showing remarkable effectivene... "This is a novel approach to the development of antiviral drugs," says Luis M. Schang, Ph.D., a postdoctoral fellow and first author on the study. "In the lab...Team finds cell gene that helps viruses multiply
... Díez. It could one day lead to antiviral drugs effective against a broad spectrum of vi...rolling RNA viruses," says Díez. "Using antiviral drugs to attack the viral multiplication process, which mutates more slowly than some other viru...Virus study reveals how nature 'super-sizes' tiny structures
...nd may someday help scientists find ways to design antiviral agents, he says. The viruses -- Chilo iridescent virus, a virus that infects the rice stem borer insect, and Paramecium bursaria chlorella virus type 1, a virus that infects certain freshwater algae -- are among the largest known viruses. They are ab...Researchers glimpse polio virus as it enters host cell
...proaches. In addition to possibly leading to new antiviral therapies, Hogle believes there could be a more immediate payoff. "Ultimately the trickle down comes in that every time we understand something about how viruses enter cells, we understand something more about the way that cells work," says Hogle. ...High percentage of Hepatitis C patients take herbs and vitamins, according to Rush survey
...re diagnosed each year. Patients are treated with antiviral therapy, which has been found to be effective in 1...he patients surveyed were undergoing treatmentwith antiviral therapy for their condition. In response, Rush asked 60 patients between April and June 1999 about ...Scientists discover new candidate drugs for treating HIV infection
...ltures. In fact, one peptide called T-20 hasshown antiviral effects in Phase I clinical trials when injected i...mega doses ofthese drugs are needed to achieve the antiviral effects. "We hope that our technology will enable scientists to find a drug that has manyof the at...Scientists clear hurdle in effort to destroy experimental brain cancers with viruses
Curbing immune system's antiviral response allows anticancer agent to reach, attack ...ug cyclophosphamide suppressed the immune system's antiviral response. Inhibiting this responseallowed a modified strain of herpes simplex virus to reach the bra...Inhaled drug useful in preventing flu
...s by JAMA and Glaxo Wellcome Inc. ANN ARBOR---An antiviral drug administered once daily during flu outbreaks ...u outbreaks. "Zanamivir is the first of a class of antiviral drugs that inhibit both type Aand B influenza. Vaccines are effective and should be used, but there...Those receiving prenatal care and antiviral treatments already were more likelyto get AZT How well are medical advances translated into the community practice? Inthe case of HIV-infected pregnant women, where they get their care may matterthe most. In 1994, researchers were s...Immune Response To Hepatitis B Spares Liver Cells
... upon exposure to HBV, probablycooperates with the antiviral process that rids the blood and liver of hepatitis...nfection fully. "This tissue-sparing, noncytolytic antiviral process can be viewed as a hostsurvival strategy to control infections of vital organs that would ot...New Study By TSRI Scientists Sheds Light On Viral Clearance In Acute Hepatitis B Infection
...te HBV Infection," demonstrates thatnondestructive antiviral mechanisms can contribute to viral clearance byeli...T cell infiltration, suggesting thatnondestructive antiviral mechanisms, triggered by inflammatory cytokinessecreted by the first wave of inflammatory cells that......ether it isappropriate for them to be treated with antiviral medications." A manufactured form of interferon is the mainstay in treating hepatitis andother serious viral infections. The natural form of interferon is produced inthe body to boost immunity and regulate other cell functions. As an alternativeto in...Tip Sheet: Health Benefits Of Caffeinated Beverages
...ins) have anti-oxidative, as well asantibacterial, antiviral potency, according to the author. (Food ResearchInstitute, Fujieda City, Japan; AGFD paper 75; Wednesday, March 24, 9:35 a.m.;Hilton, Huntington A/B/C.) Antioxidants in Green and Black Tea Inhibit Atherosclerosis - Hardening of thearteries (athero......tional drug VX-497 may have potent, broad-spectrum antiviral activity, according to laboratory results presente...iruses in cell culture was compared to that of the antiviral compound ribavirin, both alone and in combination with interferonalpha. Vertex is evaluating VX-497 ...Deaths of Zoo Elephants Explained -- New Virus Identified
... zoos." Quick detection and treatment with antiviral drugs is life-saving, headded. Asian elep...ed Chandra,veterinarians at the zoo prescribed the antiviral drug famciclovir. Chandrarecovered in a few days. The Florida elephant also recovered after the same...Experimental Therapy Makes HIV-Infected Cells Commit Suicide
...ls is a therapeutic approach that could complement antiviral drugs that are currently in clinical use," Ratner says. The virus that causes AIDS uses a scissors-like protein called a protease to cut out enzymes it needs for reproduction. Drugs called protease inhibitors, which are extending many lives, ...