Dangerous Chemical Combination Presents Possible Scenario For Gulf War Illnesses
...on,there may have been thousands of deaths. But it appears that, for some veterans,the precautions prevented one set of problems and created another. Now,our task is to analyze the veterans' symptoms by investigating all the potentialcauses, not only for their sakes but for the welfare of future soldiers." ......n's disease. "Virtually every addicting substance appears to modify the dopaminesystem, implying it may have a central role in addiction," said AlanI. Leshner, director of the National Institute on Drug Abuse (NIDA). "Thisfinding provides a fundamentally new scientific tool in the arsenal to understandand u...New Cancer Switch Discovered By Duke Medical Center Pharmacologists
... for anti-apoptotic and transforming activity. Ras appears to be necessary, but not sufficient for the transforming activity of BCR-ABL." According to Pendergast, the discovery offers the possibility of cancer treatments that eliminate drug-resistance by selectively rendering tumor cells vulnerable to normal...Tumor Suppressor Gene Located In Liver Cancer Cells
... 4 percent. A report on this tumor suppressor gene appears in the December issue of Nature Genetics. Along with principal investigator Randy Jirtle, Gerald R. Hankins and Mary K. Washington of Duke University Medical Center; and Angus T. De Souza and Terry C. Orton of Zeneca are co-authors. Funding for the ...Second Breast Cancer Gene Located
...ncer, Futreal said. "Like BRCA1, the gene appears to function as a tumor suppressor gene,"Futreal said. "In these families, the normal copy of the gene is knockedout, the mutated copy is retained, and the gene loses its ability to functionnormally." The process of mapping and cloning the g...Duke Researchers Discover Candidate Susceptibility Gene For Autoimmune Disease
...he bloodstream, and instead, discovereda gene that appears to regulate the inflammatory response." Working...This finding provides insight into a new gene that appears to regulateTNFa. It is possible that defects in this gene may cause people to be susceptibleto devel...Rosemary May Have Anti-Cancer Properties
...nary rosemary -- the commonly used cookingspice -- appears to help prevent breast cancer in laboratory rats, accordingto a study in Penn State's College of Health and Human Development. Rosemary interfered with cancer's initiation phase, or the transformationof normal cells to cancerous ones. The study, di...Duke Researchers Find Second Gene Linked To Blood Vessel Disorder
... families." The protein encoded by the ALK1 gene appears to be made almost exclusivelyin the cells that lin.... While researchers aren't sure of itsfunction, it appears to interact with the potent growth factor, transforminggrowth factor beta (TGF-_). Researchers are o...New Discovery About Genes Has Implications For Genetic Therapy
... from and how they move. "This class of introns appears very primitive, as if they were the ancestors of introns found in higher organisms." Lambowitz believes that the introns are "parasites" on the genome, and behave similar to the way retroviruses inhabit an organism. He suggested that retroviruses...Researchers Find Possible New Route to Making Cancer Cells Vulnerable
... fleaon an elephant's back," said Heitman. "But it appears to be crucial.Based on our experiments, we think FKBP12 could help open and close thepump. When FKBP12 is missing, the pump may not be able to open and closeproperly to expel the drugs from the cell." The researchers say the findings could c...Nitric Oxide May Hold Key To First Treatment For Deadly Form Of Malaria, Duke Scientists Report
...es as a genetic signaling mechanism. "It appears that life uses NO ubiquitously," said the study'sleader, Dr. Jonathan Stamler, a cardiologist and pulmonologist. "Knowingthat NO compounds have the ability to turn genes on is a phenomenal understandingthat may lead to a new chapter of research and p...Genetic Alterations Linked To Cancer In Some Blood Samples
...cause the presence of DNA alterations in the blood appears to be associated with large, advanced tumors and with cancer that has spread," says lead author David Sidransky, M.D., associate professor of otolaryngology/head and neck surgery, and oncology. Sidransky cautions that the test does not appear useful...Ocean Sediments Contain Record of Past Vegetation Fires in Africa
...sediments: Climatic and geochemical significance," appears in the September issue of the journal GEOLOGY. "Biomass burning, a result of fires started by lightning strikes, is important for its relationship to climate (drier climates have more burning) and its immense effect on vegetation, and there...Nitric Oxide Found To Control Cells By Turning On Genes; Suggests New Role In Health And Disease
...es as a genetic signaling mechanism. "It appears that life uses NO ubiquitously," said the study'sleader, Dr. Jonathan Stamler, a cardiologist and pulmonologist. "Knowingthat NO compounds have the ability to turn genes on is a phenomenal understandingthat may lead to a new chapter of research and p...Component In Soy Products May Be Substitute For Estrogen Treatment
...creased significantly(by about 4.5 percent). So it appears that soy protein is beneficial inregard to cardiovascular risks even though total cholesterol didn't changesignificantly." In Belgium, John W. Erdman Jr., director of the U. of I. Division of NutritionalSciences, reported Potter's bone-density findi...Newly Discovered Gene Halts Cell Division and May Have Cancer Link
...to cancer," Dr. Benezra says. The MAD2 checkpoint appears to plays an essential role in the cell cycle, Dr. Benezra says. After a cell's DNA is copied, each pair of the duplicated chromosomes is bound together at structures, called centromeres, that fit around each chromosome like a napkin ring. In order fo...Changing Continental Runoff Patterns Could Change Ocean Circulation
...less of this greenhouse gas in the oceans. "It appears that salinity in the Tethys Sea was the mechanism that switched deep water formation from the cold poles to the warmer subtropics," says Bice. "In a future, warmer Earth, human alterations to fresh water runoff and surface salinity might have the ...North America Hit Hard By Asteroid Strike In Yucatan 65 Million Years Ago
...ge. The researchers said that biological evidence appears to support theiroblique-impact hypothesis. North America, the first region to experience thefireball, had the most severe extinctions of plants. After the devastation, ferns dominated the flora of central North America.Ferns accounted for 70 to 100 ...Northwestern Scientists Discover How Herpes Simplex Virus Infects Cells
...rate or to die. A report of the protein discovery appears in the Nov.1 issue of the Journal Cell. "Knowing how this virus penetrates lymphocytestakes researchers one step closer to understanding how recurrent herpeticdisease can occur in persons with normal immune systems and will lead todevelopment of new...Fast Measurement Technique Reveals Early Steps In Protein Folding
...econd.) The entire collapse to a compact structure appears nearlycomplete after just a few microseconds. "Unlike slower spectroscopic methods that are limited in time resolution,our technique can identify events occurring within nanoseconds," saidMartin Gruebele, a professor of chemistry and a researcher at...