New Gene Therapy Technique Results In Efficient Gene Delivery
...s by a singlereceptor. While the ALV receptor thus appears to be uniquely suited to theprotein bridge approach, EGF is only one of many possible protein partners.Young and Snitkovsky speculate the method could be used on a variety of cellsurface markers, including those found on cancer cells. They are curren...Master Molecule Forms Brains In Frogs And Elbows In Mice
...ng matter--scientists are now learning that Noggin appears to perform a vital role in the proper development ...words, Harland and his colleagues conclude, Noggin appears to do its job by keeping the activity of other cellular growth factors in check. Noggin thus permits...Obesity Gene: Possible Link To Heart Disease Risk
...l of Medicine, London. In the study, which appears in Arteriosclerosis, Thrombosis and VascularBiology: Journal of the American Heart Association, researchers measured bloodleptin levels in 74 men. They found that the higher the level of leptin themore likely the men were to have the syndrome, and t...Gene Linked To Glaucoma, Hydrocephalus, And Other Birth Defects
... two copies of each gene. The human FREAC3mutation appears to be dominant, meaning that only one "bad copy" of the gene isrequired for an increased susceptibility to glaucoma, Hogan said. "Controllingthe balance of fluid in the eye may be very sensitive to relatively smallchanges in the behavior of the mesh......le therapies based on how aggressive their disease appears as indicatedby levels of these biological markers," Dr. Tweardy. "We also have thepotential to use these markers to detect early disease, when it is most easilytreated." To measure tissue levels of TGF-" and EGFR, the UPCI research team took...Excess Thiamine May Help Tumor Growth, Research Shows
...dy by Boros and an interdisciplinary research team appears ina recent issue of AnticancerResearch . The link between thiamine and cancer was first discovered by Laszlo andthe research team last year. That study (published in Cancer Research )revealed that rapidly dividing cancer cells produce a sugar k...Crystal Structure Of Key HIV Protein Reveals New Treatment Targets
...hysicians and Surgeons, New York, N.Y. Their work appears in the June 18,1998, issue of Nature and the June 19, 1998, issue of Science. The scientists confirmed several previously known features but also found some surprises in the crystal structure of the protein. "We discovered that a largepart of the gp...Vitamin C May Reduce Angina, Heart Attack Risks
...n a person will suffer a heart attack orstroke. It appears there are also other key factors in the health of ...ly risk factor for heart disease andstroke, but it appears to be an important one." Based on the findings of this and other recent studies making similarfindin...Brain Antibodies Provide New Clues To Origins Of Tourette's
... as a cause. "However, based on familystudies, it appears that for some individuals, an additional factor is requiredto cause the disease," says Singer. One hypothesis is that people who have two copies of the Tourette's genealways develop the syndrome, while those who receive one copy of the gene,e...... named IBD1, nearthe center of chromosome 16, that appears to act in concert with the diseasegene on chromosome 1. "The prospect of finding the genes involved is exciting because we know solittle about what causes IBD," said Judy Cho, M.D., a gastroenterolgist at theUniversity of Chicago and lead author of t...A new fungal disease appears to be responsible for mass deaths in frog populations in Australia and Panama. Australian researchers from CSIRO Australian Animal Heath Laboratory in Geelong and James Cook University in Townsville were first to find the new fungus in 10 frog ...Destructive Algae Overtaking Mediterranean Waters
...erwater equivalents of plows. In fact, the plant appears to be spreading throughout the Mediterranean, primarily from fragments dispersed by fishing nets and anchors, reports Science News. "Over the eight years that we have observed this Caulerpa in the Mediterranean, we have never seen evidence of sex...Evidence From Old Tumors Foretells Which New Breast Cancer Patients Will RequireAdditional Treatment
...earsomewhat later than angiogenesis. Loss of nm23 appears to be a crucial secondevent that must occur before the cancer can spread to distant sites. While these markers are useful, they do not tell the whole story, insist theauthors, since even for those with both high angiogenesis and non-functioningnm23...Detecting Deer: New Method For Counting Population In Urban Areas
...cted the study throughout 1996 and early1997. "It appears that we will be able to keep deer numbers at Tyson controlledso that there are not too many deer for the ecosystem. "Because Tyson Research Center is located at the edge of an expanding metroarea, this study has many implications for other areas in t...UNC-CH Researchers Develop Promising Heart Research Tool
...ted about it." A report on the development appears in the June issue of the AmericanJournal of Physiology. Besides Cascio, authors are Christopher J. Hyatt,graduate assistant in biomedical engineering; and Drs. John J. LeMasters,professor of cell biology and anatomy; Barbara J. Muller-Borer, research...Depression A Risk Factor For Coronary Artery Disease In Men
...kins study has shown. "Clinical depression appears to be an independent risk factor forcoronary artery disease, even several decades after the first episode," saysDaniel E. Ford, M.D., M.P.H., lead author of the study and an associateprofessor of medicine, epidemiology and health policy and managemen...CSIRO Reduces 'Cellulite' In Oranges
...w calcium in the fruit, but surprisingly it often appears on trees which are high in calcium, and whose foliage contains high levels of the mineral." "Albedo breakdown does not affect internal fruit quality, but it makes oranges appear unsightly to consumers, down-grading their value from fresh-mark...Researchers Identify A Protein Critical For T Cell Development And Activation
...or of Rheumatology, reports thatthe protein SLP-76 appears to be critical for the development and activation ...the development and activation of Tcells." SLP-76 appears to be as important as any of the other molecules in the signalingpathway that stimulates the immune ...Pool Of Latently Infected, "Resting" Cells Established Early In HIV Infection
...the pool of latently infected,resting CD4+ T cells appears to occur around the time of the initial burst ofvirus replication seen in most patients with acute HIV infection." Drs. Chun, Fauci and colleagues report their latest findings in the July 21,1998, issue of the Proceedings of the National Academy of S...First Reproducible Cloning Of Mammals From Adult Cells Reported In Nature
... so rich in the factors that promote celldivision, appears to facilitate the nuclear changes essential for development.We will study the molecular events of this delay period in futurework." Quartet of Experiments Verifies Technique In a series of four experiments, the team examined the development ofthe...