Enzyme's "Magic" May Hold Key to Anticancer and Antimicrobial Drugs
.... Wang is hopeful that this relatively new approach to drug design will yield results. "Structure-based design is still in its infancy, so there are people who are skeptical about it," Dr. Wang said. "My own bet is that this kind of work will get better and ...Children Become Gorillas In VR Zoo
...,and we are extremely impressed with the scholarly approach taken by <AHREF="http://www.cc.gatech.edu/gvu/people/Faculty/Larry.F.Hodges.html">Dr.(Larry F.) Hodges and Dr. (Jean) Wineman, who have worked closelywith our behavior experts. "Today, we introduce the 'virtual gorilla' experience," he adde...Duke Researchers Show "Editing" Can Fix Faulty Genes In New Approach To Gene Therapy
...ore they are translated into protein. The editing approach to gene therapy ignores the defectivegenes, which are encoded in DNA and stored in the chromosomes, in favorof focusing on the specific genetic RNA messages that are translated intoprotein. Such messages are copied from the chromosomes into a portabl...New Discovery About Genes Has Implications For Genetic Therapy
...sferred is often left to chance. The new intron approach could allow researchers to insert new information at specific sites along a gene, allowing considerably more control than is now possible. Ohio State University researchers reported their findings in the May 23 issue of the British science journal ...Southern Pine Beetle Reaching Outbreak Levels In North Florida
...outbreak conditions isto remove infested pines, an approach that requires the cooperation -- andunderstanding -- of an entire community. Using this approach during anoutbreak in Gainesville in 1994 saved thousands of trees in the urbanforest, minimized use ...'Juliet' Evades Primate Center Expedition
... income from logging." The center's three-pronged approach of captive breeding, habitat protectionand education aims to preserve the animals and to encourage further ecotourismin certain areas, Glander said. The Duke Primate Center houses the world's largest collection of endangeredprimates. Duke is also th...Behemoth Animals May Follow Same Extinction Patterns
... number over the past 5 million years and only now approach extinction. Although dinosaurs and proboscideans ruled at different times, placing bothdecline curves on the same graph show that in their individual 5 millionyear periods, these giant beasts shared a very similar pattern of decline. "No one has ev...Pinpoint Gene Control Holds Promise For Nervous System Studies
...that you wish, at anyplace that you wish. This new approach allows us this level ofcontrol." Graduate stu...agecellular connections and interactions. This new approach providesa way of making small changes in one part of a network and thenfollowing changes elicited el...ORNL Microscope "Sees" Bumps That Reveal Partial DNA Structure
...se ORNL scientists are developing this new imaging approach as analternative technology for DNA mapping. They think their technique will bemore accurate and perhaps faster than conventional methods. DNA, sometimes referred to as the blueprint for life, is a nucleic acidthat carries the genetic information in ...Learning From Birds And Bees: Engineers Study Insects For Ideas On Tiny "Micro Air Vehicles"
... AirborneReconnaissance Office (DARO). "When you approach technical people with this idea, their firstresponse is that you cannot build an aircraft this small and make ituseful," said Dr. Sam Blankenship, conference co- chair and coordinatorof the "MicroFlyer" program, the <AHREF="http://www.gatech.edu/...New Vaccine Blocks Viral Entry In Cattle, May Have Implications For Human Vaccines
...cines don't keep out viruses either. Letchworth's approach builds on scientists' growing understanding of the...he virus." Letchworth also tried the conventional approach in which he injected the vaccine into muscle. When he challenged those cattle with the virus, the va...Project Shows Native Bacteria Can Destroy Widespread Pollutant In Groundwater
...taminated with TCE, McCarty said. The conventional approach to groundwater decontamination is called pump-and-...hen adsorbed onto activated charcoal filters. This approach wastes water, because the treated water is seldom reinjected into the aquifer. The contaminated char...Duke Study Shows Early Marrow Transplant Key To 'Bubble Boy' Disease Cure
...ve no immune systems to reject the transplants.Our approach avoids toxic agents and their possible complicatio... Buckley characterized the Duke researchers' approach as conservativewhen compared with recent attempts to treat SCID in utero. Neonatal treatmentbypasses...Ozone 'Chat Room' Provides Real-Time Air-Quality Research
... implemented. "Second, the interactive Internet approach has altered the way environmental research itself ...e OTAG air quality workgroup, and through this new approach to environmental research, Husar and Schichtel have been able to reach some tentative conclusions th...Cricket And Chemistry Combine To Provide New Understanding Of How Fats Work
...h team is using a novel Nuclear Magnetic Resonance approach to tag or label the point at which one of the chains or stumps connects with the "bails" of the fat. This allows them to monitor the difference in effect of enzymes on the two different stumps. The research is already in use with industrial chemi...Jefferson Scientists Discover Mechanism Of Viral Link To Disease Commonly Associated With Asbestos
...They are also working to develop a gene therapy approach to restore growth-suppressor function of the pRb2/p130 gene. To date, the treatment has shown success in animal studies and is about to enter phase 1 clinical trials in humans. Dr. Giordano was the first to identify and c...First Salmonella Vaccine For Poultry To Be On The Market Soon
...ouple of years." Curtiss has used the recombinant approach with salmonella to research vaccines that would provide immunity to humans for malaria, typhoid fever and leprosy and to livestock for a variety of diseases. Such vaccines would be especially welcome in Third World countries, where these diseases ar...Oaks' Defenses Help Gypsy Moth Caterpillar Fend Off Virus
...terpillars are not controlled. "The ideal approach for controlling both pests would be to add somethingto the virus spray that would disarm the tannin and make the caterpillarssusceptible to the virus," says Appel. "This could either stop the oxidation oftannin or inhibit the action of PPO." Further ...Gene For Last Major Form Of Batten Disease Discovered
...cated the gene using a newly developed biochemical approach to identify theenzyme missing in the disease. The...ence and Developmental Disorders at NINDS. The new approach used to identify the gene is based on knowledge that, whenlysosomal enzymes are produced, they almos......," said Chen, for two main reasons: The intrakine approach is aimed at preventing virus entry into the cell,r...tion. Therefore, the lymphocytesprotected by this approach would be truly virus-free. In contrast, all othercurrently described genetically based anti-HIV-1 ap...