Tag: "architecture" at biology news

Body hormone ghrelin, a food intake and weight gain influence, is found to promote sleep

...significance. All other sleep continuity and sleep architecture variables remained unchanged. Conclusions This study finds that the body's endocrine system may offer a means for the body to obtain deep sleep, that which contributes to the body's overall health. These findings could have important implications f...

Carnegie Mellon University chemists create versatile polymer brushes

...hich it's difficult to control the composition and architecture of the resulting compound. With ATRP, a complex po...gy allows precise control over the composition and architecture of the many structures they can create. Matyjaszewski's groundbreaking paper on ATRP, first publis...

Researchers discover structure of Nature's 'circuit breaker'

... past work has revealed many new details about the architecture and inner workings of potassium channels -- the voltage-sensing mechanism remained a frustrating mystery. "The general principle was understood that the electric field on the membrane somehow moved 'gating charges' on the channel that would somehow o...

Pathogenic yeasts and fungi: A growing health concern

...oval of SSD1 changed the composition and cell wall architecture of the yeast cell surface. The mutant yeast also evoked a more powerful response from immune cells. As a result, the researchers suggest, the immune system's macrophage cells may have misrecognized the yeasts and overreacted, provoking an imbalance i...

Benefits of lung surgery reported for emphysema patients

...emphysema, breathing becomes difficult as the fine architecture of the lung is destroyed, leading to large holes in the lung, obstructed airways and trapping of air because of reduced elasticity of the lungs. According to the NIH, emphysema costs more than $2.5 billion in annual health care expenses and causes o...

Silent DNA architecture helps block cancer cell growth

...ions of chromosomal DNA into an inactive or silent architecture called heterochromatin. To distinguish these newly identified regions of specialized DNA architecture from previously known forms of heterochromatin, the researchers dubbed such regions senescence-assoc...

Some 400 'fragile regions' of genome more vulnerable to evolutionary breaks

... already have the first rough draft of the genomic architecture of certain breast-cancer cell lines." Pevzner and Tesler also hope to drill down deeper into the genomic data, to analyze how their fragile breakage theory works when looking at smaller blocks of genetic letters. "It's not like looking at a magazine,...

Birth control for brain neurons

...ons, and they appear to contribute directly to the architecture of the adult brain. The study suggests that modulating nitric oxide levels might be an effective strategy for replacing neurons that are lost from the brain due to stroke or chronic neurodegenerative disorders such as Alzheimer's, Parkinson's, and Hu...

PNNL supercomputer fastest open system in U.S.

.... "With this machine, PNNL is providing a balanced architecture that is designed specifically for environmental, chemical and biological sciences and the priorities of DOE's Office of Science," said PNNL Director Len Peters. "The laboratory led the supercomputer industry by ordering one of the first large cluste...

Stem cells delivered into back of eye hold promise for people with retinitis pigmentosa

...ls to preserve nearly normal vascular and neuronal architecture of the retina in a disease model that ordinarily exhibits profound degeneration. Our hope is that if these results translate into humans with the disease, we would be able to maintain vision for these patients longer." Currently, there is no way to ...

NSF news tips - September 22, 2003

...tion Technology Research award to design a network architecture that integrates millions of sensors (ACI-0205445). Xiaohui Fan of the University of Arizona is a cosmologist who is studying the evolution of the universe. His NSF award is supporting an examination of data from the Sloan Digital Sky Survey to fin...

Harvard Medical School launches new department to study human biology at the level of whole systems

...cular biology to construct an understanding of the architecture of the cell and how cells cooperate across organ systems, with a predictive model of physiology as the ultimate goal." "It is worrying that we do not understand how most drugs work and essential that we know in detail how both genetic mutations and t...

From genome comparisons, UCSD researchers learn lessons about evolution and cancer

...rangements are more likely to occur and change the architecture of our genomes. Their work was based on computatio...olution (albeit incomplete) picture of the genomic architecture of a complex breast cancer genome. Human cancer cells frequently possess chromosomal aberrations (su...

Highlights of the October 2003 Journal of the American Dietetic Association

...es a decrease in mineral content, a change in bone architecture and an increase in susceptibility to fractures. A study led by researchers at the University of Utah found that low levels of physical activity are related to femoral neck bone mineral density among not only women and their daughters, but their grand...

JCI Table of Contents, November 3, 2003

...leagues disrupted Arnt in keratinocytes. While the architecture of the stratum corneum in Arnt/ mice was found to be similar to that in control mice, the permeability barrier function and the composition of ceramides were significantly different. In particular, 4-desaturated and 4-hydroxylated ceramide species we...

Stop to smell the flowers - But do it before they're pollinated

..." Dudareva suggests that differences in the floral architecture of petunias and snapdragons may account for the different mechanisms these plants use to shut down scent production, but she has not yet investigated this topic experimentally. "The differences could have to do with floral arrangement on the differen...

Microscopes provide new view for tissue engineering

...epends greatly on the composition, properties, and architecture of the scaffolds' porous interiors. Tools for simultaneously monitoring microstructure and cellular activity can help scientists to tease apart the essentials of this interactive relationship. In turn, such knowledge can speed development of tissue-e...

Structure of a Nobel-prize winning molecule: Aquaporin

... high-resolution X-ray diffraction techniques. The architecture of aquaporin Z is typical of aquaporins, with a spiral of eight oxygens providing water-binding sites inside the channel. The outer membrane and cytoplasmic ends of the channel are wider than the interior, which is long and narrow. This structure dem...

Parasite's enzyme structure helps address a public health issue

HANOVER, NH By revealing the architecture of an essential enzyme in a parasite, Dartmouth researchers are helping address a public health issue. Researchers in the laboratory of Amy Anderson, Assistant Professor of Chemistry, have unveiled the structure of an enzyme called dihydrofolate red...

Researchers seek to clone 'mad cow disease' resistant cattle strain

...ested in creating an animal that lacks the genomic architecture to code for the production of normal prions. "In order to be susceptible to prion disease, the individual has to be able to express the prion," says Eyestone, who is using the same somatic cell transfer technology to clone a cow without normal prions...

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