Cancer vaccine based on pathogenic listeria bacteria shows promise targeting metastases
..." immune response. Together, these two independent arms of the human immune system can deliver a one-two punch to cancer cells. Antigens are like a red flag to a bull -- they draw an attack from cells of the immune system -- but the strength of the immune response depends on how the flag is waved. "This i...Broken arms and collateral damage: clues to predator-driven evolution
...s. Crinoids, also called sea lilies, have feathery arms that they extend to catch bits of plankton or detr...day crinoids usually lose---and regenerate---their arms as a result of attacks by fish, Baumiller and Gahn reasoned that arm regeneration in fossil crinoids...Molecular motor myosin VI moves 'hand over hand,' researchers say
... "One is the hand-over-hand model in which the two arms alternate in the lead. The other model is the inc... we attached a small fluorescent dye to one of the arms and took a picture with a digital camera attached to a microscope to find exactly where the dye was,...Streptococcus infects humans by thwarting blood clotting
..., he said, the findings highlight the evolutionary arms race between bacteria and humans. "Clearly, if we could mutate our plasminogen so it still worked, yet was resistant to a bacterial streptokinase, it would give us an advantage," said Ginsburg. "But then the bacteria could mutate their streptokinase ...Strep disrupts blood clotting to infect humans
...researchers have captured a glimpse of the endless arms race between infectious agents and the human immun...hemophilia, the findings highlight an evolutionary arms race between bacteria and humans. "Clearly, if we could mutate our plasminogen so it still worked, y...Study finds anti-HIV protein evolved millions of years before the emergence of AIDS
...destruction. Such conflicts, often dubbed "genetic arms races," typically put pressure on both sparring partners to continually evolve new ways to outsmart and overcome each other just to stay in the game. Such genetic tugs of war also exemplify what is known among evolutionary biologists as the Red Queen......rs to characterize movements of the spine, joints, arms and legs. The researchers use customized kinetics-processing and dynamics-processing software to crunch the numbers and render 3-D movement simulations. As the simulations are viewed, the researchers can ask a series of "what if" questions about the...Vioxx in high doses causes hypertension
... a greater incidence of edema, or swelling, in the arms and legs, which can put extra strain on the heart. Griffin said that high doses of Vioxx might be particularly hard on the kidney, resulting in fluid retention, edema and a rise in blood pressure. Some doctors won't prescribe Vioxx for patients at r...Mitochondria in spinal cords is ALS target according to UCSD medical researchers
... that begin in the spinal cord and extend down the arms and legs. They found SOD1 both inside the mitochondria and coated on the mitochondria's outer components. "However, we don't know yet which is the most damaging, the mutant protein inside the mitochondria or coated on the outside," Cleveland said....Study supports association between HPV infection and head and neck cancer
...ttern in which whole or large parts of chromosomal arms were lost early in tumor development. The observed patterns support the idea that HNSCCs can be subdivided into two genetically distinct categories and that HPV infection is involved in the early development of some HNSCCs, according to the authors. ...Nanotechnology pioneer slays 'grey goo' myths
...g weapons in unprecedented quantity, leading to an arms race or war. Policy investigation into the effects of molecular nanotechnology should consider deliberate abuse as a primary concern, and runaway replication as a more distant issue." In 1986, Drexler described a powerful manufacturing system. This ...Susceptibility of mice to mousepox offers promise of smallpox protection
...y the outcome of such a longstanding immunological arms race in a mouse model of, for example, influenza. Karupiah and colleagues continue to probe the mousepox-triggered immune response. They're investigating not only interferon response, but also the killer T cell and antibody responses....Insights on stroke from the peripheral blood suggest ways to develop markers and therapies
...ke. Using small blood samples taken from patients' arms during and immediately following strokes, the researchers have found white blood cell genetic changes they believe reflect the body's fighting response to the ongoing "brain attack" of an ischemic stroke. About 80 percent of all strokes (the other ...Rewriting textbooks on DNA crossover
...in the exchange of chunks of DNA betweenchromosome arms -- a crossover. Or a break can be healed withoutexchanging DNA to give a non-crossover recombination. Recombination stabilizes chromosome pairing, and crossovers arespecifically required for the accurate distribution of chromosomesinto the gam...St. Jude researchers create image of enzyme that orchestrates natural genetic engineering
...the free arm of one person pushing into the folded arms of another person. This causes a single strand from the first chromosome to be used as a blueprint by the second chromosome. By using the invading strand as a template to make new DNA, the second chromosome acquires new genes from the first chromosom...Oldest-known arm bone found in Pennsylvania
...is the transformation of the fins of fish into the arms and legs of our ancestors. Paleontologists Neil Shubin and Michael Coates from the University of Chicago, and Ted Daeschler from the Academy of Natural Sciences in Philadelphia found a 365-million-year-old fossil that sheds light on this transformati...St. Jude shows how disorderliness in some proteins lets them interact with a diversity of molecules
...showing how a protein called p27 uses two flexible arms to help it bind to a protein complex called Cdk2-c... spaghetti hanging off each end. One of the wobbly arms binds to cyclin A, while the other arm binds to Cdk2. When p27 is by itself in a solution, the arms...Study examines whether giving good bacteria reduces infections
...roll a total of 400 patients in one of three study arms he designed. Twice a day for 10 days, patients will receive either a placebo, probiotics or probiotics in conjunction with non-digestible fibers called prebiotics, which encourage the growth and activity of good bacteria. Pairing prebiotics and probi...Rutgers researcher offers a new perspective on human evolution
...volution of genes responsible for the formation of arms and legs with the observable diversity in limb structure among humans and other primates. In the growing field of evolution and development, known as EvoDevo, the view is that significant developmental differences are due to changes in gene regulat...Data shows FUZEON does not increase lipodystrophy in pre-treated HIV patients
...There were no relevant differences between the two arms in the magnitude of changes for glucose, total cho... FUZEON. There were no differences between the two arms in the magnitude of changes for glucose, total cholesterol, LDL cholesterol and triglycerides. Small...