Tag: "arteries" at biology news
Improved medical treatment of serious heart problems focus of UH-led group
...inol mesh-like tubes used to keep clogged coronary arteries
open. A non-surgical treatment of CAD involves a ...roperties that closely mimic the behavior of human arteries
for the treatment of both CAD and AAA. These products could not have been obtained just a few years...
JCI table of contents, February 2, 2004
...rmation of thrombi in the circulation, which block arteries
and can cause heart attack and stroke. Interested in the role of the serine/threonine kinase, Akt, in platelet activation, Donna Woulfe and colleagues from the University of Pennsylvania examined platelets from normal and Akt2-deficient mice. In the ...
Use of new direct thrombin inhibitor may be as effective as current standard treatment
...es used to prevent blood clots from forming in the arteries
of the heart during certain types of chest pain and heart attacks. Warfarin is used to prevent blood clots from forming or growing larger, and is often prescribed for patients with certain types of irregular heartbeat and after a heart attack or hea...
Aging: The continuous process from birth to death
...are affected by aging, using the isolated cerebral arteries
of rats for investigation. The conclusions of the ...impairs endothelium-dependent vasodilation of feed arteries
in the soleus muscle of rats. Such feed arteries
play an integral role in control of blood flow to t...
Gene may protect against heart disease rather than be harmful as previously thought
...y increasing inflammation in the blood vessels and arteries
feeding the heart may actually protect against it ...ght, or who eat badly, and whose blood vessels and arteries
don't become obstructed by the fatty build-up called plaques. "So, there must be genetic pathways ot...
Duke researchers link nitric oxide, vessel health
...n to play a key role in controlling the ability of arteries
to constrict or relax, with changes in the endothelial lining of arteries
after being stressed. "This is the first study to attempt to link whole body production of nitric ox...
Calcium channels control coronary artery relaxation
...ck these calcium channels had constricted coronary arteries
and had fibrous tissue in their hearts, which was ...searchers performed visual studies of the coronary arteries
of the mice and measured their contractility, they found the arteries
to be irregularly shaped and c...
Calcium channel involved in coronary artery relaxation
...w a certain type of calcium channel helps coronary arteries
to relax. The study, reported in the Nov. 21 issue...r of the study, took a closer look at the coronary arteries
in mice without the calcium channel. He and his colleagues found that the coronary arteries
Estrogen receptor-a disruption and vasodilation in coronary arteries
...tric oxide (NO)-dependent vasodilation of coronary arteries
through its action on estrogen receptor- (ER-) to ... for 14 days before the mice died and the coronary arteries
were harvested. Isolation of coronary arteries
: The hearts were excised and placed in cold salin...
New technique helps shed light on progression of dementia
...archers injected the microspheres into the carotid arteries
of one group of rats and a salt-water solution into the arteries
of rats in a control group. Sarter and his colleagues used the microsphere model in order to look at...
Scripps scientists link ozone to atherosclerosis
...isease that is characterized by a hardening of the arteries
over time due to the buildup of hard plaques--fibrous tissue, calcium, fat, cholesterol, proteins, cells, and other materials--on the inner "endothelial" walls of an artery. These plaques feel something like cartilage to the touch, which explains why...
JCI Table of Contents, November 3, 2003
... mouse haploinsufficient for elastin (Eln+/-). The arteries
of Eln+/- mice had thinner elastic lamellae and an increased number of smooth muscle cell layers. The animals demonstrated blood pressure 30-40% higher than control animals. The association of hypertension with elastin haploinsufficiency strongly su...
OHSU researchers discover molecular signaling system controlling aspects of embryonic development
...he gut in flies and we are investigating it in the arteries
of mammals. It is also related to the development of heart muscle," said Joseph B. Weiss M.D., Ph.D., principal investigator and assistant professor (molecular medicine and cardiology), and Heart Research Center scientist in the OHSU School of Medici...
JCI table of contents, 15 October, 2003
... Enigmatic role for NF-kappaB in the hardening of arteries
A report in the October 15 issue of the Journal o... causes the progressive narrowing and hardening of arteries
over time. An initiating event in the development of atherosclerosis is the accumulation within vess...
Vascular disease and aging
... disease pertains to the disorders that affect our arteries
and veins. For the three most common types of vascular disease --carotid, aortic and peripheral aging is a major risk factor. Recent studies suggest that pathological changes not only predispose the vasculature to disease but also impair compensator...
JCI Table of Contents
... elusive. Increases in smooth muscle tone of major arteries
causes the narrowing of arteries, which leads to chronic increases in blood pressure. Recent studies have suggested that calcium channels and calcium-activated potassium channels (BK channels), which facilitate the passage of calcium and potassium io...
Grant funds research to develop tissue-engineered solutions for heart disease
...treatments to increase muscle strength and replace arteries
blocked by heart disease could have significant positive impact on patient care. To reach this goal, planned projects of the grant combine the expertise of University of Pittsburgh faculty in stem cell biology, tissue engineering and imaging in what ...
Blood tests identify patients on dialysis at high risk for death from cardiovascular disease
...t within blood vessels that makes hardening of the arteries
more severe. "I think just the process of going on dialysis, having your blood drawn across a dialysis membrane and the fact that many patients on dialysis have chronic infections raises levels of this marker," says Dr. deFilippi. The senior autho...
New prospects for treating muscular dystrophy: Stem cells restore muscle in MD mice
... the researchers injected mesoangioblasts into the arteries
of mice lacking the alpha sarcoglycan gene. This gene is one of several that, when defective, cause a type of MD called limb-girdle muscular dystrophy. The researchers detected a significant portion of the normal mesoangioblasts in the muscles downst...
Injection prevents blinding blood vessel growth in mice
... been implicated in tumor growth, hardening of the arteries
and arthritis. A clinical trial sponsored by Regeneron Pharmaceuticals is being planned to assess the medication's effects in people with diabetic retinopathy and macular edema, and in patients with wet age-related macular degeneration. The stud...
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