Tag: "arteries" at biology news

Innovative method for gene therapy of heart disease shows promise in animal studies

...f gene therapy that would protect injured coronary arteries from further damage and possibly even treat the un...metal scaffolds that are now implanted in diseased arteries to hold the vessels open for improved blood flow. In cell cultures and in pigs, a team led by a res...

African Americans fare less well than whites after stroke prevention surgery

...nner lining of the carotid artery, one of the main arteries supplying blood to the brain. Blocked carotid arteries are one of the most common causes of stroke. "Previous studies have shown that CEA is performed le...

Study shows way to grow new blood vessels in the heart

...t attack, blockage in coronary arteries leaves a portion of the victim's heart tissue without oxygen, a condition called ischemia. When this happens, part of the heart tissue begins to die ...

Genetic defect in sporadic cases of the lung disorder pulmonary hypertension

...PR-II from tissue samples taken from the pulmonary arteries of the 50 patients. They found different BMPR-II defects in 13 of the 50 people studied, each of which would be capable of changing signals among cells that may be vital for their growth. Three of the patients had inherited the defect from thei...

Tiny microchips have big promise in fighting serious diseases

...surgery on 60 patients. Surgeons in the study took arteries from the patients' chest walls and sewed them on to their hearts. Robotic surgery has the advantage of precision, as it "can gain access to very small areas inside the body," he said. Michler envisions using robotic surgery to place microchips inside...

Beyond the French paradox

...d by partial or complete clogging of the coronary arteries that nourish the heart. Atherosclerosis refers to...d by partial or complete clogging of the coronary arteries that nourish the heart. This blockage can choke the blood supply to areas of the heart, resulting ...

Balanced diet lowers homocysteine, reducing risk of heart disease

...roke. Homocysteine can injure the cells that line arteries and stimulate growth of smooth muscle cells, narrowing the channel for blood flow. It also can disrupt normal blood-clotting mechanisms, increasing the risk of clots that can lead to heart attack or stroke. In a three-month study of healthy adults,...

Scientists identify gene that causes fatal lung disease

... of blood vessels in the lungs, similar to clogged arteries in the heart. "It's in the Transforming Growth Factor Beta (TGFb) family, which is a large family of different proteins that regulate cell growth and proliferation," said Dr. James E. Loyd, professor of medicine and one of the researchers. "TGFb ...

MetaPhore reports general anti-inflammatory surface treatment for biomedical materials

...ems after stents are inserted into their unclogged arteries are among the growing number Americans with medical implants who may benefit from a general anti-inflammatory surface treatment for biomedical materials reported for the first time today in the Journal of Biomedical Materials Research. Some estimate...

Novel test pinpoints location of rare insulin disorder to guide surgical cure in newborns

...performed. This involves infusing calcium into the arteries of the pancreas to determine the location of the abnormal cells. Pediatric surgeons then remove only the defective portion of the tiny organ. Children's Hospital is currently the only medical center in the United States that conducts the acute insuli...

UH lab identifies first gene mutations in blood vessel disease

...x, or space between cells, of the skin, retina and arteries become calcified and lose their resilience. Onset of the disease is usually signaled first by a rash of yellow papules on the skin, especially around the neck, groin and thighs. In more advanced forms, the skin sags and wrinkles, giving the appearanc...

Hormone replacement therapy (HRT) may protect against cognitive decline in women 65 and older who have a certain genetic make-up

...d wall thickening or atherosclerosis. The carotid arteries located on either side of the neck carry blood to the brain. "Less atherosclerosis may prevent small vessel strokes that result in mental deterioration as we age," said Yaffe, adding that this mechanism needs further study. The researchers studied ...

Alexion and Yale discover harmful complement activation in patients with acute coronary syndrome

...ent activation occurs specifically in the coronary arteries of patients with acute coronary syndrome," stated Michael W. Cleman, M.D., Professor of Medicine and Director of the Interventional Cardiology Service at Yale, and co-author of the study. "While current therapies for ACS patients are directed at atte...

Protein that stimulates blood vessel growth also helps repair broken bones

...EGF can sprout new blood vessels to bypass blocked arteries in patients with inoperable heart disease. Blood vessel growth, known as angiogenesis, is also thought to help deliver the chemicals needed for bone cells to rebuild after a fracture, says Jill Helms, PhD, DDS, assistant professor of orthopedic su...

Cholesterol levels not necessarily indicative of cardiac health

...o were diagnosed with serious blockage of coronary arteries and had bypass surgery after complaining of chest ...xty-three percent had at least 70 percent of their arteries blocked -- enough to warrant bypass surgery. Of the 506 men who had a bypass, only 71 (14 percent) ...

Laser light from Free-Electron Laser used for first time in human surgery

... to remove tiny brain tumors near vital nerves and arteries that aretoo risky to pursue with conventional medical lasers or by traditional brain surgery. The role of the Vanderbilt FEL center is to explore and refine medical uses for infrared laserlight. Some of these applications will be based on the clean ...

Moderate alcohol consumption may reduce your chances of a heart attack

...eart disease (CHD), which occurs when the coronary arteries become narrowed or clogged andcannot supply enough oxygen-rich blood to the heart. High amounts of a clotting protein calledfibrinogen - levels of which tend to increase as people grow older - are associated with coronaryartery, cerebral vascular an...

Smoking especially dangerous for individuals with gene that causes coronary artery spasm

...itric oxide activity was deficient in the coronary arteries of patients with coronary spasm," says Yoshimura, lead scientist on the study. "From there we decided to target the eNOS gene to find a genetic cause of coronary artery spasm." In the study, Yoshimura and colleagues compared risk factors and gene...

Heart transplant surgeon at Cedars-Sinai specializes in implanting mechanisms that allow a defective heart to rest while awaiting a transplant

...was followed by a balloon angioplasty to clear the arteries to the heart,but after the latest heart attack, which occurred this past February, physiciansat his hometown hospital told Nuckols that his options were limited. "They said that my heart was so badly scarred after those heart attacks thatthey didn't ...

Enzyme discovery may link underlying processes in cancer and heart disease

...o theformation of plaques seen in hardening of the arteries (atherosclerosis) and inthickening of the blood ve...eveloped to treat cancer, reverse hardening of the arteries or treat high bloodpressure, including drugs designed to block this type of enzyme or treatmentsthat...

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