UC Santa Cruz Public Forum on the Human Genome
...here, researchers at UCSC played a crucial role in assembling the genome sequence, and they continue to have a major role in the ongoing analysis of the human genome. "UC Santa Cruz scientists launched consideration of this vast project in 1985 and then, 15 years later, played a key role in the integration o...Berkeley chemical engineer wins national award for catalysis research
... highly skilled construction workers of chemistry, assembling one product after another from starting materials without becoming part of the final structures themselves. Without them, reactions that produce plastics, pharmaceuticals and a host of products simply could not happen. The spectroscopic techniques ...Human genome analysis hints at new proteins involved in gene expression
... search for genes that encode proteins involved in assembling the mRNA splicing machinery, the scientists found "significantly greater complexity than is found in Drosophila ." And, in searching for genes that encode proteins involved in adding the poly(A) tail to mRNA, the researchers unexpectedly found new g...Amidst genome data, a practical tool for researchers
...s doing the sequencing to check their results when assembling the genome sequence," said Dr. Cheung, who co-authored another paper in the special issue of Nature reporting on the assembly of a whole-genome physical map....Human disease gene survey yields underlying principles
...iscern general patterns." The scientists began by assembling a list of 923 genes that caused inherited disease, drawing the list from the seventh edition of Metabolic and Molecular Bases of Inherited Diseases and from the Online Mendelian Inheritance in Man database. Next, they categorized each disease gen...NIGMS awards 'Glue Grant' to create virtual cell
...aling molecules have been identified in cells, and assembling a catalog of all of the possible -- and more importantly, authentic -- interactions among them is a mind-boggling feat. "Advances in genomics, proteomics, and informatics make the timing right for this bold experiment in how science is conducted," sa...Chemists report new approach to synthetic fragments of medically important Heparin
...rsors can be used either as donors or acceptors in assembling larger Heparin structures," said chemist Geert-Jan...size 80 to 90 percent of the Heparin structures by assembling these building block into larger structures. Heparin is a mixture of polysaccharides with different...Research to give authorities new tool in tracking terrorists
...apability to trace explosives, the researchers are assembling and analyzing samples of TNT from a wide variety of origins. The idea is to create a database for authorities to refer to when investigating suspicious TNT explosions, Yinon said. If successful, similar databases could be created for other explosives...Five Seattle scientists selected as Howard Hughes Medical Institute investigators
...sed in the Human Genome Project for processing and assembling DNA sequencing data, making the genetic maps used to localize the genes for genetic diseases, and identifying genes and other biological features in the genome sequence. Green is a professor of molecular biotechnology and an adjunct professor of comp......ng the RNA folded within it into telomeric DNA and assembling it on the ends of the chromosomes. Telomeres maintain the stability of chromosomes in numerous ways and, much like chemical bookends, prevent them from unwinding. But in a fine illustration of nature's ingenuity, they also play a role in regulating...Using new FDA regulations, Kellogg takes the lead in promoting heart-health benefits of folic acid
... support from Kellogg Company, was responsible for assembling the scientific panel that reviewed the research. "Kellogg Company has a long-standing tradition of applying the latest research to provide consumers with foods that meet their demand for health benefits as well as taste," said Johnson, Kellogg USA. ...New enzyme tied to tangles in Alzheimer's disease
...sed of the long protein tau. Normally, tau'sjob is assembling and maintaining the microtubules that stretch from one end ofthe nerve cell to the other. Microtubules keep the long nerve axons healthy fromthe muscle to the brain by transporting cell nourishment and structuralcomponents. Tau can be deraile...Under the hood of a cellular transport machine
...clathrin/. Clathrin-coated vesicles are constantly assembling and disassembling to performtheir task of transporting proteins from the outside of the cell inside. They are responsible for importing LDL cholesterol, and they play a role in breastcancer through internalization of a key receptor. During disease...'Altered state' may be responsible for creating important brain chemicals
... of messengerRNA), which is used as a template for assembling proteins in biological systems. The system works this way: When the enzyme making RNA, called RNApolymerase, moves along the DNA double helix, it leaves behind underwound DNA. Selected sequences in this DNA temporarily become left-handed Z-DN...Fetal Lead Exposure May Reduce Immunity
...ity" during development, when the immune system is assembling its defenses and disruption by lead could produce persistent damage to immune defenses. In addition to Dietert, the lead studies were conducted by Capt. Thomas E. Miller, USAF, a Cornell graduate student at the time of the experiments; Karen A. G...How Did Life Begin? Biochemical Evolution On Chemical Surfaces
...g aluminum would provide the catalytic centers for assembling organic molecules into polymers. "For many ...ace could have provided the catalyticframework for assembling them into polymers and protecting them fromdestruction by the sun. A famous experiment perfo...Cellular Engineers Design Custom Cell Surfaces Able To Adhere To Synthetic Materials
...ropriate the cell's natural metabolicmachinery for assembling tailor-made oligosaccharides." Bertozzi reasoned that if a properly designed synthetic sugar with novelchemical properties could be ingested by the cell, the sugar might beincorporated in an oligosaccharide and delivered to the surface. The r...New Molecular Switch Is The Key That Unlocks DNA Repair
...se mismatch recognition signals. This occurs by assembling the repair machinery which then orchestrates the correction of these errors. “Without hMSH2 or hMLH1 the cellular DNA becomes unstable [genome instability], errors accumulate and the result is cancer,” Dr. Fishel explained. ......ple helix but they have only been able to do so by assembling together expensive, carefully crafted, chemical bu...ands) that they were 100% sure could do the job of assembling the final complex but useful structures. These carefully designed ligands are designed to have very ...... linking death or damage to oil exposure. Also, by assembling this group of scientists, we now have a blueprint for who should be mobilized in the event of a similar situation." Rebar became involved with the project in 1989, when project scientists found abnormalities in the sea otters' blood. Snyder joined th...