Tag: "asta" at biology news

Cancer vaccine based on pathogenic listeria bacteria shows promise targeting metastases

Berkeley -- An experimental cancer vaccine using defanged listeria bacteria is showing great promise in animal studies, successfully treating new cancers that have spread into the lungs of mice....... by scientists at Cerus Corp. in Concord, Calif., employs a genetically engineered listeria bacteria based on a strain created by coauthor and University of California, Berkeley, microbiologist Dani...

Researchers identify distinctive signature for metastatic prostate cancer

Howard Hughes Medical Institute researchers have identified a telltale change in cellular machinery that could help clinicians predict whether prostate cancers are likely to spread or remain relatively harmless in the prostate. ...The researchers found that a cellular signaling molecule called Hedgehog, which drives normal development and regeneration of prostate tissue, is greatly activated in...

Congress to fund Sequim-based coastal security research effort

SEQUIM, Wash.--A $4.2 million Congressional appropriation...will fund a new coastal security program designed to develop advanced sensors capable of providing early warning of biological, chemical or nuclear material releases in marine and coastal environments. The research program will be based at Pacific Northwest National Laboratory's Sequim Marine Research Operations facility in Sequim, Wash...

Genetic model for devastating form of paraplegia suggests new treatments

A new genetic model for a motor disorder that confines an estimated 10,000 people in the United States to walkers and wheelchairs indicates that instability in the microscopic scaffolding within a key set of nerve cells is the cause of this devastating disability....The study, which is published in the July 13 issue of the journal ...HSP--also known as familial spastic paraparesis and Str...

Treating metastatic disease with a modified herpesvirus

Using bacteria or viruses to control tumors is an old idea, and many such biotherapeutic agents have been designed and tested in cell and animal models. Safety concerns are paramount in this work, and most candidates with oncolytic properties have remained sidelined at the preclinical stage because, despite a general tropism towards cancer cells, they retain some ability to infect normal host cel...

New insight into cancer metastasis

CAMBRIDGE, Mass. (June 21, 2004) Scientists know a great deal about how tumors originate and develop, but relatively little about how cancer manages to metastasize and invade distant tissues and organs. Now, a team of researchers led by Whitehead Member Robert Weinberg has discovered that tumors spread by reactivating and commandeering a "sleeper" protein that should have been shut off permanent...

Fox Chase discovery may help physicians diagnose, treat devastating childhood disease

Researchers at Fox Chase Cancer Center have made a crucial discovery that may help physicians better diagnose and treat children with Hirschsprung disease, a debilitating and sometimes life-threatening ailment that causes bowel obstruction and involves an array of genetic changes. The report will be published in the advance online publication of ...Developmental biologist Myung K. Shin, Ph.D.,...

Wilex & Fox Chase Cancer Center begin trial w/ novel compound targeting tumor invasion & metastasis

Wilex AG, Munich, Germany, and Fox Chase Cancer Center, Philadelphia, Pa., announced today the start of a clinical trial with a novel compound, WX-UK1, targeting tumor cell invasion and metastasis. This Phase I trial marks the start of an innovative collaboration between the U.S. government, an academic research center (Fox Chase) and a biotech firm (Wilex) to rapidly move a laboratory discovery...

Patagonia's coastal wildlife receive a protective boost by Argentine government

NEW YORK (APRIL 8, 2004) --Three-ton elephant seals, boisterous southern sea lions, and some of the world's largest penguin colonies recently received a protective boost, when the government of Argentina signed a comprehensive plan to safeguard its 2,000-mile coastal zone from harmful development activities, including overfishing and unregulated tourism. ...The agreement marks a significant miles...

City rain run-off poses threat to coastal water users

Rainwater running off city roofs and streets poses health risks to surfers and others who spend time in coastal waters, according to a new study. ... ...Spending more time in the surf increased risk of fever, stomach pain, vomiting, diarrhea, skin infection, eye redness and other symptoms, according to the report in the American Journal of Public Health. ... ..."These potential health risks w...

Devastating parasitic weed may be felled by toxin borrowed from flies

The parasitic weed, broomrape, attaches to the root of such vegetable crops as tomato, potato, beans, and sunflowers. With no need for leaves of its own, it produces only a floral shoot above ground. Meanwhile, its host is barely able to survive, much less be productive.... ...Now, the defense mechanism of another pest the fly may provide a weapon against parasitic weeds.... ...Researchers from...

Scientists discover that metastases share a similar genetic profile to their primary tumour

Hamburg, Germany: Work by scientists in The Netherlands has contradicted the notion that breast cancer metastases behave differently to their primary tumours....... PhD student, Britta Weigelt told the meeting of the 4th European Breast Cancer Conference today (Thursday 18 March) that, contrary to what had been thought previously, any primary breast cancer cell was capable of producing secondary...

Researchers model embryo implantation and tumour metastasis in fruit flies

...TORONTO (March 11, 2004) - A research team at The Hospital for Sick Children (Sick Kids) led by Dr. Howard Lipshitz has discovered that a protein previously linked to mammalian embryo implantation, as well as tumour metastasis, plays similar roles in fruit fly development. This research is reported in the featured article in the March 9, 2004 issue of the scientific journal Current Biology......

Migraine mouse provides insight into neurobiology of devastating headaches

Scientists have created a mouse model for migraine headache that may serve as an invaluable tool for future study of these debilitating headaches that are often accompanied by severe neurological symptoms. The research, published in the March 4 issue of Neuron, is a major step towards development of more successful treatments targeted at specific neurobiological events that underlie migraines.......

Rb protein's role in retina development is key to understanding devastating eye cancer

The finding that a tumor-suppressor protein called Rb is required for proper development of the mouse retina is a major step toward understanding why some children develop the devastating eye cancer called retinoblastoma. This discovery should eventually help scientists design a better treatment for this disease, according to investigators at St. Jude Children's Research Hospital. An article abou...

URI oceanographer awarded NSF grant to study function of jellyfish in coastal ecosystems

URI Graduate School of Oceanography biological oceanographer Dr. Dian Gifford and collaborators Dr. John Costello, Providence College, and Dr. Sean Colin, Roger Williams University, have been awarded an $860,400 grant by the National Science Foundation to study the ecological function of small jellyfish (hydromedusae) in coastal ecosystems. The three-year project will begin on June 1.... The foc...

California pistachio industry threatened by potentially devastating disease

St. Paul, Minn. (January 9, 2004) The California pistachio industry produced approximately 300 million pounds of pistachios in 2002 and continues to grow each year at an impressive rate. However, plant pathologists with The American Phytopathological Society (APS) say a serious and devastating disease could put a definite halt to this relatively young industry. ...... According to Themis J. Mi...

Metastasis of colon cancer cells reversed in vitro

Weizmann Institute scientists have succeeded in reversing the metastatic properties of colon cancer cells, in vitro. The findings, published in the Nov. 24 issue of The Journal of Cell Biology, uncover a key process involved in the metastasis of colon cancer cells and raise hopes that target-specific drugs might be devised to prevent, or reverse, the invasive behavior of metastatic colon cancer c...

Bush Administration plan to reduce global warming could devastate sea life

KINGSTON, R.I. -- November 17, 2003 -- A Bush Administration proposal to mitigate the effects of global warming by capturing carbon dioxide emissions from power plants and injecting it into the deep sea could have disastrous effects on sea life, according to a University of Rhode Island researcher. ... Brad Seibel, assistant professor of marine biology at URI, said that while the Administration's...

Anti-platelet drug blocks bone metastases in mice

St. Louis, November 3, 2003 -- Researchers at Washington University School of Medicine in St. Louis have dramatically slowed the metastatic spread of a highly malignant tumor in mice by disabling platelets with an experimental drug.... ...Based on earlier experiments, scientists had hoped the drug, ML464, would block the spread of a melanoma cell line into bones. They were pleasantly surprised to...

Duke ecologist finds devastation, hope in Iraqi marshes

DURHAM, N.C. -- An expedition by Duke University wetlands expert Curtis Richardson to evaluate damage to Iraq's storied Mesopotamian Marshlands revealed an environmental disaster of vast proportions. However, he also found the potential for restoring a significant portion of the marshes and with them the Marsh Arab culture. ... On his June 16-26 trip, he encountered dust-bowl-level desiccation wi...

Finicky snails provide new clues to the evolution of coastal ecosystems

Whether sauted in wine or steamed in the shell, mussels have long been a favorite of seafood lovers. For most people, the type of mussel served isn't important - as long as there are plenty of them on the plate....... But in the wild, it's a different matter. According to a new study in the journal Science, when it comes to preying on mussels, marine snails are often pickier than people....... Th...

New method for predicting prostate cancer and the risk for metastasis

A new study, to be published this week in the online edition of the Proceedings of the National Academy of Sciences, has shown that in about 40% of men older than 50 the DNA of the prostate is damaged. This damage closely resembles that found in the DNA of prostate cancer. This cancer-like DNA could readily be identified using biopsy tissues and is believed to indicate a high risk for prostate...

Proposed treatment for diabetes could have devastating side effects

New research, published in open access journal BMC Immunology, reveals that a prospective treatment for autoimmune diseases such as diabetes and multiple sclerosis can result in serious side effects in mice. The researchers from Stanford University found that 86% of the diabetic mice they treated with peptide immunotherapy died as a result....... In humans type 1 diabetes is a serious autoimmune...

New research tools are opening the 'black box' of coastal ecosystems

DENVER, CO Characterized by unimaginably complex, three-dimensional currents and sharp, shallow reefs too hazardous for oceanographers to navigate, coastal ecosystems have traditionally been a mysterious "black box." ... ...But, at least four emerging research tools in oceanography and marine ecology are now opening new doors to shed light on coastal ecosystems, researchers noted in a peer-revie...

Scientists crack the black box of coastal ecosystems

DENVER, CO Scientists along the coasts of Washington, Oregon and California have cracked the black box of coastal ecosystems, revealing the inner workings of the near-shore marine environment. Working on a scale from microscopic fish larvae to the 1200 mile long California Current that sweeps the west coast of the United States, an interdisciplinary team of over 100 ecologists, oceanographers, g...

An origin of new world agriculture in coastal Ecuador

New archaeological evidence points to an independent origin of agriculture in coastal Ecuador 10,000 to 12,000 years ago. Suddenly, the remains of larger squash plants appear in the record. The Las Vegas site, described by Dolores Piperno of the Smithsonian Tropical Research Institute (STRI) and Karen Stothert, University of Texas at Austin in the February 14th issue of Science, may predate pla...

Effects of rare, devastating disease linked to shrinking of cells' telomeres

BOSTON - Scientists at Dana-Farber Cancer Institute and their colleagues have found that much of the widespread damage that the rare genetic disease ataxia telangiectasia, or AT, wreaks on the body results from the progressive shortening of telomeres, the structures that cap the ends of a cell's chromosomes.... ... In genetically altered mice, the researchers found that the shortening of telomere...

OXiGENE announces commencement of Phase I/II clinical trial of Combretastatin A4 Prodrug

WATERTOWN, Mass.-- Jan. 7, 2003-- OXiGENE, Inc. (Nasdaq: OXGN, SSE: OXGN) today announced the initiation of a Phase I/II combination study of its lead vascular targeting agent (VTA), Combretastatin A4 Prodrug (CA4P), in patients with advanced cancer of the lung, head & neck and prostate. These cancers accounted for an estimated 192,500 deaths in the United States in 2002. CA4P became the first VT...

Global warming has uneven effect on coastal animals

(Santa Barbara, Calif.)Although it is expected that populations of many organisms will move away from the equator and toward the poles to stay cool during global warming, researchers have found that the intertidal zone does not exactly fit this pattern. A study published in this week's Science Magazine indicates that there may be "hot spots" at northern shoreline sites within the next three to fi...

UCI Samueli School researchers to study wetlands impact on coastal water quality

Irvine, Calif., Aug. 13, 2002 -- A team of Southern California researchers led by Stanley B. Grant, an environmental engineer in The Henry Samueli School of Engineering at UC Irvine, has been awarded a $640,000 grant from the UC Office of the President to study how coastal wetlands affect the levels of fecal pollution along the Southern California coast. ...... Working with Grant on the project a...

Amazonian devastation: Common sense quantified to predict disaster

Threats to Amazonian forests are no news, but a team led by William F. Laurance of the Biological Dynamics of Forest Fragments Project and the Smithsonian Tropical Research Institute pinpoints specific causes of forest destruction in hopes of stemming the tide. Human population density, distance to the nearest highway and dry season severity best predict the extent of deforestation, the group rep...

Researchers developing technology to outsmart metastasized cancers

WEST LAFAYETTE, Ind. News that a malignant tumor has spread to other parts of the body seems like a death knell to the ears of many cancer patients. But Endocyte Inc. and Purdue University researchers are developing treatment methods that ultimately may cure some cancers, even those that have reached an advanced stage................ Many types of cancer cells have a great affinity for folate...

Molecular study questions Pfiesteria's link to coastal fish kills, threat to public health

(Embargoed) CHAPEL HILL - Coastal fish kills and a potential threat to public health previously linked to the single-celled marine creature Pfiesteria piscicida may be a case of mistaken identity.... Using new molecular detection methods, a study headed by a University of North Carolina at Chapel Hill scientist found no indication that the Pfiesteria life cycle as originally described is unusual...

New coastal research center to aid wildlife conservation in Texas

HOUSTON, June 4, 2002 A new conservation and research center established by a private ranch and the University of Houston will provide a location for environmental studies aimed at protecting the natural resources and wildlife on the Texas coast. ...... The Fennessey Ranch, a 4,000-acre privately owned wildlife habitat near Corpus Christi in Refugio County, has partnered with the University of H...

Icebergs devastating impact on Antarctic marine life revealed by satellite data

For the first time, satellite imagery has allowed scientists to observe how icebergs in a remote corner of Antarctica can disrupt an entire marine ecosystem....... Using data from three orbiting satellites, researchers have been monitoring a Connecticut-size iceberg called B-15 that broke from Antarcticas massive Ross Ice Shelf in March 2000. Within a few months, B-15 had fractured into smaller...

MGH researchers unravel structure of a key protein involved in tumor angiogenesis and metastasis

Cancer cells need a blood supply to grow. A key receptor protein called the alpha V beta 3 integrin directs formation of new blood vessels by binding to other proteins, such as angiostatin and endostatin, produced by tumor cells. Scientists at Massachusetts General Hospital (MGH) have now deciphered the detailed structure of this protein as it interacts with its ligand (the protein that binds to...

Proliferation of Argentine ants in California linked to decline in coastal horned lizards

The pesky Argentine ant, which has proliferated throughout the coastal regions of California, invading homes and displacing native species of ants, is also contributing to a sharp decline in the state's population of coastal horned lizards.... In separate papers published this month in the journals Conservation Biology and Ecological Applications, a team of San Diego biologists show that...

University of Southern Mississippi $6 million grant will aid coastal waters research

OCEAN SPRINGS -- University of Southern Mississippi scientists here are leading the way ...on a $6 million project that will use estuarine plants and animals to signal changes in Gulf of Mexico ...coastal waters. ... The goal of the four-year project is to use microbes, fish, crabs, shrimp and other species -- ...bioindicators -- to measure how well estuaries are functioning and the impact o...

Fly cells on the move may reveal clues to cancer metastases

Using neat genetic tricks with fruit flies, scientists from Johns Hopkins School of Medicine have found the key signal that allows a group of normally stationary cells in the ovary to travel, they report in the current issue of Cell....... Because fruit fly genetics are similar to but vastly simpler than human genetics, understanding the signals that mobilize the ovary cells may help clarify...
(Date:11/26/2014)... 25, 2014 (HealthDay News) -- Parents need to take ... concussions, an expert warns. Parents must make sure ... standard, Dr. David Dodick, chair of the American Migraine ... Clinic College of Medicine in Scottsdale, Ariz. in an ... release. Any coach involved with teens sports needs ...
(Date:11/24/2014)... 24, 2014 Global electrophysiology devices ... by 2020, according to a new study by ... cardiac arrhythmias clubbed with growing global geriatric population ... Though still in the budding stage, the electrophysiology ... usage rates in the recent times, with physicians ...
(Date:11/24/2014)... Residents of retirement communities in Ohio and ... GOT TALENT, an annual online talent competition and showcase ... classic crooners, to seniors partying on a “night on ... living young. , “SENIORS GOT TALENT, while still having ... has always been about highlighting the vibrancy of being ...
(Date:11/24/2014)... Westbury, New York (PRWEB) November 24, 2014 ... recently contacted by the Family and Children's Association ... products such as soap, shampoo, mouthwash and other such ... senior citizens who are home bound, living in nursing ... are intended to greatly enhance the well being of ...
(Date:11/24/2014)... 2014 SafeHandles™ announced that they will ... Ed Begley Jr, airing via Discovery Channel. Dates and ... a passive, non-invasive, replaceable, and affordable germ protective device. ... shrinkable sleeves and adhesives to promote hand hygiene in ... core of SafeHandles is the desire to make a ...
Breaking Medicine News(10 mins):Health News:Parents Need to Take Lead on Teen Concussion Prevention 2Health News:Electrophysiology Devices Market Worth Forecasted To Reach $6.19 Billion By 2020: Grand View Research, Inc. 2Health News:Electrophysiology Devices Market Worth Forecasted To Reach $6.19 Billion By 2020: Grand View Research, Inc. 3Health News:Electrophysiology Devices Market Worth Forecasted To Reach $6.19 Billion By 2020: Grand View Research, Inc. 4Health News:Nursing Homes & Assisted Living Retirement Communities Enter Seniors Guide's Seniors Got Talent 2Health News:Nursing Homes & Assisted Living Retirement Communities Enter Seniors Guide's Seniors Got Talent 3Health News:The Holiday Inn Westbury - Long Island gives back to the local Long Island community, and also goes beyond borders to assist those in need during the 2014 Holiday Season 2Health News:The Holiday Inn Westbury - Long Island gives back to the local Long Island community, and also goes beyond borders to assist those in need during the 2014 Holiday Season 3Health News:New Episode of Innovations TV Series to Feature SafeHandles™ 2
Other Tags
activationblindingblocksassembledrainperuvianmahoganywarfarindependentsmokeddisorderedcenteredtraditionalbackfirecanapproach