Gene clusters predict atherosclerosis severity, susceptibility
...predict with 93.6 percent accuracy the location of atherosclerotic lesions. "This study is the foundation of futu...e researchers then "mapped" not only the degree of atherosclerotic plaque development, but also the locations of the plaque within the aorta. Location of the plaque is...JCI table of contents: 1 September, 2004
... distinct effects on initiation and progression of atherosclerotic lesions AUTHOR CONTACT: Karin E. Bornfeldt University of Washington School of Medicine, Seattle, Washington 98195, USA Phone: 206-543-1681; Fax: 206-543-3644; E-mail: bornf@u.washington.edu View the PDF of this a...Penn scientists identify novel pathway in aneurysms
...f Pennsylvania School of Medicine have shown in an atherosclerotic animal model that susceptibility for developing an... the outer layer of blood vessels not in the fatty atherosclerotic lesions of the inner layer, as expected. (Macrophages engulf such foreign objects as cellular debris...JCI table of contents, 2 August, 2004
...uct. Mice treated in such a manner showed reduced atherosclerotic lesion size. The increase in the natural antibody ...-5 links adaptive and natural immunity in reducing atherosclerotic disease AUTHOR CONTACT: Alan Daugherty University of Kentucky, 900 S. Limestone Rd, Lexington, KY 4...UCLA researchers recreate patterns formed by mammalian cells
...ng of how artery cells calcify and turn to bone in atherosclerotic heart disease. "Our ability to recreate cell patterns may ultimately help us learn how to better control them, leading to new ways to treat certain conditions like heart disease," said Demer....Atherosclerosis treatment needs to go with the flow
Branch points in the arteries are a common area of atherosclerotic disease, resulting in the occlusion of both branches. These branch points can generally be defined as a main branch and a side branch, and, in treating the disease, the question of what is the optimal course of action, opening the main branch, the s...JCI table of contents, 1 June 2004
...Branch points in the arteries are a common area of atherosclerotic disease, resulting in the occlusion of both branches. These branch points can generally be defined as a main branch and a side branch, and, in treating the disease, the question of what is the optimal course of action, opening the main branch, the s...Variation of gene associated with decreased risk of heart attack and stroke
... are thought to be caused by rupture of vulnerable atherosclerotic plaques, they are recognized to be complex disorde...ffer protection against clinical events related to atherosclerotic plaque rupture," the authors write....JCI table of contents, 16 February 2004
...oprotein APOE play an important role in preventing atherosclerotic disease. This protective role is associated with the ability to modulate plasma lipid levels, but recent evidence also suggests that APOE and HDL are able to stop the proliferation of aortic smooth muscle cells, which have been implicated in atherosc...Gene may protect against heart disease rather than be harmful as previously thought
... not exclusive to these fatty streaks, also called atherosclerotic plaques, but is generally activated when tissue is... are known as Apo E knockout mice. The severity of atherosclerotic disease is seen in varying degrees among different strains of Apo E knockout mice. Genetic differenc...Scripps scientists link ozone to atherosclerosis
...ting evidence for the production of ozone in fatty atherosclerotic plaques taken from diseased arteries. Lerner is Li...l the "atheronals." These atheronals were found in atherosclerotic plaques that were surgically removed from patients with atherosclerosis. The scientists suggest the...JCI Table of Contents, November 3, 2003
...N and ApoE demonstrated a significant reduction in atherosclerotic lesion size and macrophage content in the vessel w...here hypocholesterolemia is the man trigger of the atherosclerotic process. Atherosclerosis-associated inflammation of the arterial wall also appears to play a fundame...Cellular fat sensor slows heart disease
...reduces inflammation and discourages the growth of atherosclerotic plaques. "The lesions that cause atherosclerosis are very complex, and are aggravated," said Evans. "We believe that PPAR-delta normally acts as a molecular soldier to guard against inflammation and disease. Unfortunately, these good effects are com...Tips from the Journals of the American Society for Microbiology
...t that infections at remote locations can modulate atherosclerotic events distantly." (A. Jain, E.L. Batista, Jr., C. Serhan, G.L. Stahl, T.E. Van Dyke. 2003. Role for periodontitis in the progression of lipid deposition in an animal model. Infection and Immunity, 71. 10: 6012-6018.)......n the treatment of neurological, neuromuscular and atherosclerotic disease. "We know that creatine plays a pivotal role in maintaining energy levels in the brain," says Dr. Rae. "So it was a reasonable hypothesis that supplementing a diet with creatine could assist brain function." The experiment tested this hypothe...Scientists find genetic link between blood flow patterns and cardiovascular disease
...nges in blood flow patterns and the development of atherosclerotic plaques. The discovery could help explain how inc...s, and less direct flow are more likely to develop atherosclerotic plaques than are vascular areas with straight and unobstructed blood flow. Dr. Jo hypothesized that...Automated imaging of brain tissue, high-quality glimpses inside arteries
... Hospital. (Paper CMBB3, Intravascular imaging of atherosclerotic plaque with optical coherence tomography, Monday, June 2, 4:15 PM) ULTRAFAST LASER AUTOMATES MICROSCOPIC-SCALE BRAIN IMAGING In work that may accelerate progress in an important field of biology, researchers have experimentally demonstrated automat...Gene variation in immune system cells lowers heart disease risk
...lled fractalkine. Fractalkine, sometimes found in atherosclerotic vessels, attracts immune system cells bearing CX3C...d tissue. The NIAID scientists speculated that in atherosclerotic tissues, fractalkine might attract immune system cells and encourage them to bind to the walls of bl...American Physical Society March Meeting 2003
...ystem which can potentially detect inflammation in atherosclerotic plaques and a possible early sign of esophageal cancer; (2) low-coherence interferometry (LCI) that can improve physicians' ability to locate breast cysts during a biopsy procedure known as fine-needle aspiration; and (3) "spectral encoded confocal m...Get your blood moving: Increased blood flow could lead to healthier blood vessels
... cells can clump and stick at these hot spots for atherosclerotic plaque formation," said Diamond. "Perhaps, elevated blood flow may alter these disease prone regions to relieve some of the localized inflammation."...