UNC scientists develop new way to calculate stability of proteins
...3-D images have provided a database of how all the atoms in the building blocks interact in many thousands of different proteins. These imaging experiments sometimes facilitate the analysis of what happens to proteins if specific amino acids are altered to create protein mutations or variants. Using this...Molecular structure could advance understanding of human disorders
...ded the crystal with X-rays, which bounced off the atoms within the crystal. By collecting and analyzing th... critical for an accurate picture of how the 5,981 atoms in the complex are assembled....Nature's chemical weapons save lives
...s the number and mode of attachment of the various atoms in the compound. Once the structure of the compound is known, researchers can then focus their studies on developing a way to synthesize these compounds from simple organic building blocks in a concise and economical fashion. This becomes especially...Rice center to study therapeutic and environmental imapct of nanotechnology
...sed on a scale ranging from the size of individual atoms to that of large molecules....Study by Boston College chemistry team shows critical role of water in protein function
...o (180 K), consists of clusters of protein surface atoms and solvent water that move in a coordinated fashi...mperature." Since the early 1980s, protein surface atoms were described as having an ensemble of states with nearly equal energy, not a single arrangement at...Researchers uncover a piece of nature's secret nitrogen formula
...mental chemistry of iron compounds that have three atoms attached to each iron, but an unexpected chemical ...ct its structure. The X-rays diffracted around the atoms like sunlight bending through the crystals in a chandelier. A computer scans all the diffractions to...Molecular motor packs DNA into viruses at greater than champagne pressures, researchers report
...rces of repulsion encountered when pushing charged atoms close together, and the forces of entropy that make anything resist being constrained in a tight space. For nearly four years, Bustamante and his colleagues at the University of Minnesota tried pulling on the DNA as it is being stuffed into the capsi......ng the microscopic constituents of matter: ions, atoms and molecules. In a 1999 paper published in ...es that are part of the DNA backbone and certain atoms of the nucleo-bases. "The electron holes in the DNA simply don't like to be near the positivel...Researchers describe atomic-size 'sorter' that performs vital cellular function
...ercellular travel. Ions, the electrically charged atoms that power many vital functions, traverse cell membranes through specialized proteins called ion channels. The proteins provide pathways between the inner part of the cell and the exterior. The selectivity filter is the essential part of the pathway...Study: tree coring seems to be quicker, cheaper method of measuring radiation
...each sample. Natural uranium has a ratio of 137.88 atoms of 238 for every one atom of 235, Coleman said. The depleted form what is left over after an enrichment process used for making nuclear fuels and bombs has a ratio of about 500 to one. Trees suck up water beneath the ground and store the radioactiv...Science: nanoscale 'Trojan Horse' attacks cancer cells from within
...eted alpha particles to cancer cells using bismuth atoms generated outside of cancer patients. Radioactive ...y) of 46 minutes. This short window of potency for atoms generated outside the patient meant that the bismuth therapy was limited in its delivery to only the...PNNL science, technology help keep America safe
...illed tubes. PUMAs glass fibers contain lithium-6 atoms and cerium ions that detect the presence of radionuclides. The neutrons react with the lithium isotope to leave an ionization trail through the glass matrix, which results in light emission from the cerium. PUMA is being commercialized by Nucsafe o...Ancient Chinese folk remedy may hold key to non-toxic cancer treatment
...iron, a chemical reaction ensues, spawning charged atoms that chemists call free radicals. The free radicals attack cell membranes, breaking them apart and killing the single-cell parasite. About seven years ago, Lai began to hypothesize that the process might work with cancer, too. Cancer cells need a ...Enzyme studies at Brookhaven Lab may lead to new antiviral agents
...rce (NSLS). The pattern of x-rays bouncing off the atoms reveals the three-dimensional molecular structure. In the current studies, Stony Brook University graduate student Mary Lynn Baniecki characterized the binding of the cofactor to the protease, identifying which parts bind to the enzyme and which part...Prizes awarded in the 2002 Gottfried Wilhelm Leibniz Programme
... occur on the microscopic leval, for example among atoms or molecules. But they can also be found in macroscopic systems, such as in turbulence in currents, a field of research that Bruno Eckhardt has been increasingly concentrating on recently. He has developed numerical methods of simulating flow pattern...Science's Top Ten: nanoscale computing circuits named top scientific advance of 2001
...te (BEC), a "superatom" of trapped and supercooled atoms in quantum lockstep, was published in a landmark Science article in 1995. Science authors Eric A. Cornell and Carl E. Wieman were awarded the 2001 Nobel Prize in Physics for their work, sharing the prize with Wolfgang Ketterle of MIT. The buzz ab...Scientists identify molecular structure of cancer-related proteins
... powerful computer to analyze the way in which the atoms scattered the X-rays. The resulting data were used to produce a three-dimensional picture of the proteins. The X-ray crystallography of the proteins was conducted at the National Synchrotron Light Source (NSLS) at the US Department of Energys Brookh...Potato technology may help move mail
...ecules and releases one atom. Some of these single atoms attach themselves to a standard oxygen molecule. T...form of oxygen - ozone - that carries three oxygen atoms instead of the standard two. The highly unstable nature of ozone is both its bane and balm. The ins...Roll call: Study shows how bacteria signal a quorum
...d found a small pocket that contained a cluster of atoms they knew must be AI2. He then used the nearby LuxP atoms and other clues to deduce the identity of each AI2 atom. One atom of the 16 proved particularly di......se to one molecule (cAMP), letting charged calcium atoms inside the odor neuron. The channel closes as the calcium entering the cell turns around and inhibits it. Bradley's experiments revealed that when CNGA4 is present, the odor channel closes within one second of opening. Without CNGA4, it takes 10...