Tag: "atrial" at biology news

Gene therapy alternative to calcium channel blockers

... As many as 2.2 million Americans are living with atrial fibrillation (one type of rhythm problem.) Arrhythmias can occur in a healthy heart and be of minimal consequence, or they can lead to more serious heart disease, stroke or sudden cardiac death. According to statistics from the Heart Rhythm Society...

Study may improve survival of transplanted livers

...tive effect," said Lemasters. One of these agents, atrial natriuretic factor, has been shown to protect agai...tack."Our next step is to test our hypothesis that atrial natriuretic factor will be protective against ischemia-reperfusion injury in the liver," said Kim. ...

UCSD finds genetic time bomb in heart that leads to heart failure in some patients

... familial forms of congenital heart disease called atrial septal defects, even after the malformation is sur...ppel of Vancouver, Washington who was born with an atrial septal defect in 1970. Although surgery at age 5 repaired the structural defect, he experienced irr...

Nicotine exposure in aging hearts

...tine. However, serious and sometime fatal cases of atrial fibrillation (AF) have been reported in patients w...rry for patients with heart disease. How specific atrial substrates control and modulate atrial vulnerability, which can induce atrial tachycardia (AT) and A...

Patients with atrial fibrillation undertreated for stroke risk

...a stroke or dying after being newly diagnosed with atrial fibrillation, a common heart rhythm problem affect...of Medicine. "In short, not enough patients with atrial fibrillation at recognized risk for ischemic stroke receive warfarin (Coumadin) therapy, and patient...

Chronic alcohol abuse damages regulating hormones

... regulating hormones - arginine vasopressin (AVP), atrial natriuretic peptide (ANP), aldosterone and angiote... in alcoholics during long-term abstinence. Since atrial natriuretic peptide, or ANP, as well as aldosterone and angiotensin II are counter-regulatory or cou...

JCI Table of Contents, May 1, 2003

...e withcardiomyocyte-restricted inactivation of the atrial natriuretic peptidereceptor guanylyl cyclase-A AUTHOR CONTACT: Michaela Kuhn University of Muenster, Muenster, Germany. Phone : 49-251-83-52597 Fax : 49-251-83-55501 E-mail: mkuhn@uni-muenster.de View the PDF of this article at: https://www.the-j...

Estrogen linked to more efficient regulation of a woman's heartbeat

...mplanted cardiac pacemaker, frequent occurrence of atrial fibrillation, premature atrial or ventricular contractions, or other forms of arrhythmia. Nonlinear analysis of short-term resting ...

A pilot study may offer promise of a marker for ovarian cancer

...nal spread is present at diagnosis. Background The atrial natriuretic peptide (ANP) influences the tone and ...ions of the fluids and tissues. ANP is secreted by atrial myocytes as a 126 aminoacid molecule and divided into different fragments, namely proANP(1-30) (NtAN...

Genetic variants put some patients at risk for particular drug reactions

...o prevent blood clotting due to conditions such as atrial fibrillation (irregular heart rhythm). "After we identified these patients' genotypes, we looked back at their medical records to determine if they had had severe bleeding incidents while they were taking warfarin," Veenstra said. "We looked at ...

Study shows that aspirin and warfarin are equally effective for stroke prevention

...ent stroke in patients whose stroke was related to atrial fibrillation (AF) strokes caused by clots coming ...in in preventing recurrent stroke in patients with atrial fibrillation was confirmed in SPAF, greater insight was needed to determine optimal therapy in preve...

First gene therapy to calm pigs' out-of-sync hearts

...ly and chemically stimulated the hearts to produce atrial fibrillation, a serious arrhythmia. In atrial fibrillation, both upper heart chambers quiver chaotically, up to 600 times a minute. This overwhel...

University of Pittsburgh researchers develop computer system to predict impending arrhythmia and sudden death

...on," he said. Researchers found that prediction of atrial and ventricular tachyarrhythmias was accurate 80-90 percent of the time. They could predict the onset of the arrhythmia as long as four to eight hours before the event. This research is part of a collaborative effort between the University of Pittsb...

Study shows cognitive decline is not normal in aging

...ckness withultrasound, major ECG abnormalities and atrial fibrillation from ECG. Cognitive function is defined as the intellectual process by which onebecomes aware of, perceives, or comprehends ideas. It involves all aspects ofperception, thinking, reasoning and remembering. The cognitive tests use...

Treatment restores normal heart rhythm in patients

...ores normal heart rhythmin all study patients with atrial fibrillation ANN ARBOR---Researchers from the Un...heart rhythms in 100 percent of study patientswith atrial fibrillation through treatment with an ibutilide fumarate injectionprior to an electrical shock to t...

Cardiac surgery patients at higher risk

...iacsurgery. They found that arrhythmias, including atrial fibrillation, during andafter surgery doubled when a patient's serum potassium level fell below 3.5millimoles per liter (mmol/L). At levels below 3.3 mmol/L, the need forcardiopulmonary resuscitation (CPR) also doubled. Investigators concluded that s...

UB Researchers Identify Specific Oral Bacteria Most Likely To Increase Risk Of Heart Disease

...-artery disease, congestive heart failure, angina, atrial fibrillation,myocardial infarction or mitral-valve prolapse in both groups. Results showed that patients with moderate or advanced periodontaldisease had a greater prevalence of cardiovascular disease than patients with noperiodontal disease, gingiv...

Gene Orchestrates Heart Chamber Development

...on patterns of the myosin proteins. They know that atrial myosin heavychain-1 gene (AMHC1) is expressed only in the atria, for example, whilethe ventricle myosin heavy chain-1 gene (VMHC1) is restricted to theventricles. It has not been clear how expression of these genes is restricted toone chamber or ...

Researchers Identify Gene That Sets Boundaries For Heart Chamber Development

... prevent theexpression of an atrium-specific gene, atrial myosin heavy chain-1 (AMHC1),suggesting that Irx4 works to maintain the boundaries between the heartchambers. "Before Irx4, there was no way into the problem of how these chambersget set up. Irx-4 now gives us a tool to understand the broader...

Irregular Heartbeat Shown To Increase Risk Of Death As Well As Disability; Particularly Harmful To Women

...HeartAssociation. According to the study, men with atrial fibrillation (AF) had a risk of death1.5 times gre...d specifically at death rates and foundpeople with atrial fibrillation had an increased risk of death. "Women tend to live longer than men," says the study's ...

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