Learning how cell's tiny motor powers its mobility
...are only certainpoints where kinesin molecules can attach to a microtubule. Basically, the neck linker zippers up andthrows its rearward partner forward to the next attachment site, like swinging the rear leg forward tothe next steppingstone." According to Vale, the linked kinesins take step after step al...Jefferson scientists use gene repair technique to change albino mice hairs to black
...ligonucleotide that has the capability to find and attach itself to a certain part of a gene. The small genetic vehicle is designed to trigger the cell's normal DNA repair system into action as well. The repair mechanism scans the DNA looking for any mismatches or two strands of DNA that don't seem in sync....Pitt team first to illustrate mechanisms of chromosome missegregation in cancer cells
...osite poles of the cell. Thread-like microtubules attach each of the chromatids to the centrioles, forming the spindle. When the cell divides, the chromatids separate and are pulled by the microtubules to opposite poles. Thus, two identical pools of chromatids, the inherited genetic instructions of the f...Brookhaven scientists create new ways to tag and track molecules
...s they need, they use organic chemistry methods to attach a variety of organic molecules around the outside. "By varying the organic molecules surrounding the metal cluster, you can tailor-make the label to bind to the molecules you want to study," Hainfeld says. So scientists can design labels that bind...Chemical probe reveals ultrafast movements of DNA proteins
... Other scientists have had to attach probes to the outside of the DNA helix so the measurements they've gotten are not as precise, he said. Coleman and Madaras designed the probe on computer, then created i......rs Society have also developed sampling devices to attach to luxury yachts. These monitors collect data on everything from temperature to phytoplankton levels. Simpler modules will be fitted to racing yachts during next year's round-the-world Volvo Ocean Race. This should reveal how robust they are with the...Toxicologists discover traces of diesel exhaust in the body
...1-nitropyrene, one of the organic substances which attach themselves to the core of particles of carbon in the diesel soot. In the human body, the organic compounds and the carbon core disintegrate and are then metabolized. Toxicologists are able to detect the degradation product of 1-nitropyrene amongst th......approach the swimming behemoth in a small boat and attach a camera to its back with a suction cup. The Weddell seal team (Williams, Davis, Fuiman, and Horning) set up camp on the frozen surface of Antarctica's McMurdo Sound and drilled through 15 feet of ice in sub-zero temperatures so they could work with ...ZymoGenetics discovers potential new therapy for autoimmune diseases
...ody's immune system by producing antibodies, which attach to foreign matter and initiate a normal immune response. In diseases of autoimmunity like lupus, B cells go awry and produce antibodies that attack the body in a destructive manner. In SLE patients, the amounts of these circulating antibodies become...Blister beetles use sex and subterfuge to infiltrate bee's nests
...docopulation, the larvae use pincher-like limbs to attach themselves to the underside of the duped bees. These males then deposit the larvae on to female bees during further mating attempts, a process called venereal transmission. "By first attaching to a male bee, triungulins have access to multiple femal...Study shows receptor molecule facilitates introduction of corrected genes into cells
...o make the virus look like something else that can attach to airway cells and have the capacity to penetrate inside," he said. "Dr. Kreda's paper shows there actually are these receptors on the side of cells facing the airways and that if you can dress up viruses with UTP, you can fool the cells into openin...Arctic ozone depletion linked to longevity of polar stratospheric clouds, according to studies
...e non-reactive. But if there is a surface area to attach to like the polar stratospheric cloud ice crystals, the chlorine compounds change into ozone-gobbling chlorine radicals in late winter and early spring after reacting with sunlight. The greenhouse effect, which warms Earth near its surface, may ...Spiders get better web sites by rising early
... spiders with egg sacs have special needs, as they attach their egg sacs to lines near the orb web. Once the sacs are in place, the females cannot move them. Thus the females have to stay put and guard the eggs, or they will be parasitized. That's why large females with eggs build much earlier than thos...UC Berkeley study shows gecko foot hairs are amazing dry adhesives
... College in Portland. "When a gecko runs it has to attach and detach its feet 15 times a second. We think we know how it does that so rapidly." In order to measure the extremely tiny forces involved when one hair sticks to a surface, Full and Autumn teamed up with two engineers, Ron Fearing at UC Berkeley a...DNA details suggest how human chromosomes break, rearrange and cause a genetic disease
...tions where broken pieces of chromosomes 11 and 22 attach to each other in a rearrangement called a translocation. The researchers found unusually frequent sequences of adenine and thymine, two of the four chemical letters in the genetic alphabet that spells out the body's blueprint. These repetitive stretc...Molecular structure key to allergies and asthma is identified
...s for antigens, molecules foreign to the body, and attach to antibody receptors on the surface of immune sys...t would be easier to find inhibitor molecules that attach to the antibody, thereby preventing the key from fitting into the lock." The gene for the IgE rece...Alcohol researchers suggest specific binding site for anesthetics and alcohols
...l, Ph.D. (Stanford University), developed a way to attach an anesthetic analogue called propanethiol to amino acid residues at a specific site in glycine and GABAA receptors. GABA and glycine receptors are the primary mediators of inhibitory neurotransmission in the brain and spinal cord. The new work ad...Molecular-scale roughness identified as factor in bacterias ability to stick to surfaces
...dual microorganisms and the surfaces to which they attach and also to measure directly their topography and adhesion properties. He and co-author Karl Shellenberger, a master1s degree candidate in environmental engineering, presented their findings Tuesday, Aug. 22, at the national meeting of the Americ...DNA-based flu vaccine raises protective immunity
...model. Influenza virus uses the HA glycoprotein to attach and gain entry into cells. In developing vaccines, researchers target HA because raising anti-HA antibodies provide protection against the virus. The use of the C3d subunit of complement combined with HA to prime the immune system against influenza c......and disease. However, researchers say they hope to attach many other types of biological entities, such as cells and DNA, capable of quickly detecting a wider range of substances, either in the body or in laboratory samples. The polymer micropatterning development represents a possible means of gluing the...