Award winning researchers reveal potential new role for Glivec
...benefit patients by tailoring their treatments and avoiding unnecessary therapy and often toxic 'trial and error' probabilistic prescriptions. It will also aid regulatory agencies and pharmaceutical companies by speeding up drug development while helping to implement more rational regulatory policies." Dr Mc...No role for simian virus 40 in human pleural mesotheliomas
...e a caution to other researchers to be vigilant in avoiding these technical errors when planning future studies with SV40. "Because SV40 was a recognized contaminant of some polio and adenovirus vaccines in the 50's and early 60's, its potential to cause cancer in humans has been a source of intense debat...A probable cause for high blood pressure identified - shows links with diabetes
... pressure and diminish the onset of diabetes while avoiding other side effects."...The search for a kinder, gentler chemotherapy
...maceutical payload, killing the tumor from within, avoiding the destruction of healthy cells responsible for much of the damage caused by traditional chemotherapy. The research is published in the August 25 edition of the Journal of the American Chemical Society. "We've developed a class of particles called c...Mouse study shows NPAS3 and NPAS1 genes may be linked to psychosis
... this way. Instead, the mutants dart about wildly, avoiding interaction with their normal siblings. In addition, the mutant mice do not have a normal startle response, and have a distinct reduction of a protein called reelin in their brains. Other researchers have shown in postmortem examinations of the bra...UCSD biologists develop 'super-endurance' strain of mice
...g the sensation of exhaustion and is important for avoiding muscle damage during extended exercise." The researchers note in their paper that high levels of mitochondrial enzymes and low amounts of lactate are typically observed in humans with phosphofructokinase deficiency and McArdle's disease. These indivi...Study explains spatial orientation differences between sexes
...his could mean that women are better than males in avoiding the worst-case scenario in spatial orientation, as women act more cautiously due to the way they interpret the sensory input, while men tend to take risks. An example, says Tremblay, is piloting a plane in a situation where visual cues have been lost...MSU group reviews Berkeley venture into brave new science funding world
... general direction of the university. We recommend avoiding these kinds of agreements in the future. While most of the concerns of critics did not materialize, this type of agreement is just asking for trouble and is going to get you more grief than benefits." The group of 10 MSU experts essentially conducte...Gene therapy alternative to calcium channel blockers
...ng the benefits of calcium channel blockers, while avoiding the negative side effects of existing pill therapies, especially on other organs of the body. Our initial results with gene therapy are very promising." The researchers were drawn to investigating the role of Gem because of its key role in an enzyme...Asian bird flu became highly pathogenic through continued circulation and gene swapping
...allenging task, the recent success of Hong Kong in avoiding H5N1 poultry outbreaks due to preventive measures taken demonstrates the wisdom of this approach. The culling of hundreds of millions of poultry across East Asia reduced the threat of transmission of bird flu to humans, and possibly even prevented t...Noah's modern ark: The role of ART in conserving endangered species
...ingly, in the wild. ART has huge implications for avoiding the loss of genetic diversity, by moving eggs and sperm between institutions or for breeding animals that fail to mate naturally." The need to maintain adequate genetic diversity is why cloning is of little or no use in conserving endangered species,...Salmonella infects cells and saves itself by altering host membrane lipids
...elegant strategy for surviving and replicating and avoiding this cellular disposal system," said Galan, the Lucille P. Markey Professor of Microbiology, and Chairman of the Section of Microbial Pathogenesis. "We found that these bacteria alter the lipid composition of the vacuole, or compartment, they are in ...Espionage may have driven the evolution of bee language according to UCSD-led study in Brazil
...ation within the hive may have evolved as a way of avoiding espionage by competitors. Nieh's most recent stu...n both cases. The victim species avoids attack by avoiding resources marked by the aggressor species. On the other hand, exploiting the discoveries of other s...Breast cancer patients failed by treatment with taxol and taxotere respond to abraxane
...s with the natural protein "transporter" albumin, avoiding the need for toxic solvents and detergents like those used in Taxol and Taxotere. By eliminating these toxic elements, patients treated with Abraxane do not typically need routine premedications. The previously reported pivotal Phase III trial dem...Scientists identify cells that lead to retinoblastoma
...a that target these first cancerous cells, thereby avoiding the difficult side effects that patients suffer from treatments such as radiation therapy and chemotherapy. "From the first cancerous cell to the malignant tumour, there are a chain of events that must occur for a person to develop cancer, which must...Concerns remain about UVB damage to amphibians
...ould avoid the effects of UV-B radiation simply by avoiding sunlight or laying their eggs in deeper water," Blaustein said. "But that ignores millions of years of evolution, in which amphibians have developed certain types of behavior for specific reasons. Some species lay their eggs in warm, shallow waters b...Innovative 'self healing' bandage to help diabetics
... products which can be used in the patient's home, avoiding visits to outpatient clinics altogether. Sheila MacNeil, CellTran's Research & Development Director and Professor of Tissue Engineering at the University of Sheffield, says; "we are moving the technology through to clinical use as quickly as we can a...JCI table of contents, 17 May 2004
.../press/20762.pdf ACCOMPANYING COMMENTARY: Sepsis: avoiding its deadly toll AUTHOR CONTACT: Thomas Decker University of Vienna, Vienna, Austria. Phone: 43-1-4277-54605; Fax: 43-1-4277-9546; E-mail: thomas.decker@univie.ac.at View the PDF of this commentary at: https://www.the-jci.org/press/21819.pdf ****...American Lung Association's 2004 State of the Air report ranks cities and counties with dirty air
.... These simple and concrete action steps include avoiding exercising outside on high pollution days and not burning wood or trash. The American Lung Association also urges taking steps to help clean up the air, including carpooling and filling gas tanks after sundown, as well as supporting strong national,......ge house sparrows from nesting. These tips include avoiding the use of filler grain, such as milo, millet or cracked corn, at bird feeder stations -- all favored foods of House sparrows. Since house sparrows can be common around human habitation, TBN recommends placing nest boxes away from heavily trafficked ...