Researchers discover how worms' noses sense oxygen
Berkeley - Organisms ranging from bacteria to humans navigate environments that can contain d...ive Biomedical Research (QB3), determined that the bacteria the worms feed on are at a higher density around the border of the dish, consuming oxygen along with...UNC research accelerates discovery of novel gene function
...ed allows us to take candidate genes from virus to bacteria to cell to animal, quickly and efficiently." The t...g the changes and place it into an animal model or bacteria for further study....Gene alteration points to longevity, thinness
...uit fly by feeding C. elegans specially engineered bacteria that knock down the activity of Indy. Their model netted a 15-20 percent increase in lifespan in addition to the other benefits. Unlike true genetic knockouts, with scientists completely removing both copies of a gene so 100 percent of function is g...Bacterial protein recycling factor possible key to new class of antibiotics
...lled ribosome recycling factor (RRF) in the common bacteria Escherichia coli. This image reported in the June...biotics such as erythromycin and tetracycline kill bacteria but are virtually harmless to humans, showing little side effect despite their influence on mitochon...Bacteria spill their guts to aid researchers in quest for new antibiotics
...ientist is trying to develop a drug that will kill bacteria by interfering with gating. Dr. Blount and his col... often conserved, studying the gating mechanism in bacteria may help scientists better understand the process of mechanosensation in humans, Dr. Blount said....Finding the hole in the defenses of cavity-creating microbes
Forcing the bacteria in our mouths to choke on their own acids may offe...nter who have discovered a chink in the armor that bacteria use to survive the hostile environment of the human mouth. Streptococcus mutans or S. mutans, the d...Researchers recommend new approach to combat drug-resistant staph infections
...n be used in combination therapy. RIP prevents the bacteria from being virulent by inhibiting a target protein... the production of toxins by Staphylococcus aureus bacteria through a complicated cell-to-cell communications process. Taking this knowledge to the next level, ...Tips from the journals of the American Society for Microbiology
...y acids may be effective at controlling Salmonella bacteria in chickens say researchers from Belgium and the C...use of food-borne infections in humans, Salmonella bacteria is most commonly associated with poultry. Currently, short-chain fatty acids are being used to trea...Flies may taste bitter better, first map of insect 'tongue' reveals
... landing on spoiled apples infected with different bacteria could select those less likely to cause harm when ingested. In mammals, taste receptors on the tongue can detect five primary flavors: sweet, bitter, sour, salty and umami -- a savory or meaty taste. The sense of taste plays an important role in mamm...Salmonella infects cells and saves itself by altering host membrane lipids
...rt a new and fundamental mechanism that Salmonella bacteria use to replicate within body cells and cause disea...e June 18 issue of Science . Most dangerous bacteria that enter the body are engulfed and digested by cells called macrophages. Once inside a macrophage,...TIGR president discusses significance of finding anthrax toxin
...text of the comparative genomics of this family of bacteria and offer insights into the physiology and evoluti...e-encoded proteins that may help explain why these bacteria are pathogenic and also may identify important targets for vaccines and drugs. But the genome analy...Nanotechnology pioneer slays 'grey goo' myths
...tem. This "assembler" would use robots the size of bacteria to join individual molecules into products. Assemblers would be highly productive, because small things can move quickly. The products would be precise and strong because molecules are small and uniform, and form strong bonds. For all these reasons, ...Common worm provides insights into salmonella virulence
...ied specific genes within Salmonella that give the bacteria its ability to infect host cells. They said their ...la's "molecular syringe" that are required for the bacteria to have maximum potency in infecting the worm, known as Caenorhabditis elegans. The virulence factor...Protein engineered to detect nerve gas
...ting with corresponding proteins from thermophilic bacteria -- known for the robustness of their proteins -- that live in hot springs. The biochemists are also launching efforts to design proteins to detect other nerve agents, including sarin. "One particularly important aspect of this computational design te...NASA researchers customize 'lab-on-a-chip' technology
...ight Center in Huntsville, Ala., watch fluorescent bacteria flow through tiny, fluid highways on a dime-sized ...hip technology can be used for new tools to detect bacteria and life forms on Earth and other planets and for protecting astronauts by monitoring crew health an...Mutant biological machine makes proteins but can't let go
... machine that are identical in every species, from bacteria to humans. Because they sit where the protein chain is actually built, these "universally conserved" nucleotides in the ribosome were thought to help that process. Unexpectedly, Johns Hopkins researchers have discovered that these four nucleotides ar...Does antibiotic use contribute to allergies?
...otics for 5 days to weaken the naturally occurring bacteria in the GI tract before experimentally introducing the yeast Candida albicans. Increased growth of C. albicans is a common side effect of antibiotic therapy. The mice were then exposed to mold spores. Those that had received antibiotic therapy and...U-M scientists use 21st-century technology to probe secrets of M. tuberculosis
...of M. tuberculosis in the lungs is to surround the bacteria with immune cells called macrophages, which signal...tructures called granulomas are enough to stop the bacteria from spreading. Although the individual will always be infected with TB bacteria, the disease will r...Antibiotics alter GI tract microbes and increase lung sensitivity to allergens
... a unique microbial fingerprint a specific mix of bacteria and fungi living in our stomach and intestines," s... in the U-M Medical School. "Antibiotics knock out bacteria in the gut, allowing fungi to take over temporarily until the bacteria grow back after the antibioti...Molecular image of genotoxin reveals how bacteria damage human DNA
...s to design new drugs to fight the wide variety of bacteria that use this toxin. The toxin, called cytolethal distending toxin, or CDT, is used by bacteria that cause a range of diseases, from typhoid fever to diarrhea. And unlike any other bacterial toxin...