Enzyme's "Magic" May Hold Key to Anticancer and Antimicrobial Drugs
...hopefully sooner--we should see more drugs based on this approach." Please acknowledge partial funding for this work from the National Institute of General Medical Sciences (NIGMS), a component of the National Institutes of Health that supports basic, non-disease-targeted research...Key to Triplet Repeat Brain Diseases Open Door For New Way To Understand, Treat Genetic Diseases"
...roduced by these genes interact ina different way, based on the number of repeated amino acids, producingdevastating consequences." "The novel insight is that this extra domain produced by triple repeatsacts in the same way across all these diseases," Vance said. "Eventhough we don't know what the normal ...Duke Researchers Show "Editing" Can Fix Faulty Genes In New Approach To Gene Therapy
...o contributedto the work. Sullenger's strategy is based on the discovery, more thana decade ago, that instead of being simply a passive carrier of geneticinformation, the genetic material known as RNA is an active participantin editing genetic messages before they are translated into protein. The editing...Duke Researchers Find Second Gene Linked To Blood Vessel Disorder
... to heal inresponse to injury. While a treatment based on Marchuk's work may be some years down the road,he emphasizes that for the first 98 years since the disease was describedin the medical literature, virtually nothing was known of its underlyingcause. Now in two years, Marchuk and his colleagues hav...Race Plus Roaches: A Breathtaking Link
...r of the study. Eggleston speculates that racially based genetic differences, important in the regulation of immune responses, hold a clue. Low socioeconomic status forces families to live in substandard housing, whether urban or suburban, he says. Older homes, or those in crowded areas, give cockroaches a......and it contains the only knownchemoautotrophically based terrestrial community," said ThomasKane, professor...n had beenthought." To prove that the food web was based entirely on chemicalenergy and not solar energy, Kane, doctoral candidate SerbanSarbu and assistant ...Cornell Researchers Precisely Date Wood From Ancient Tomb In Turkey
...re article's coauthors. "That level of precision, based on the fact that trees put on a single growth ring per year, is unique." The researchers supplemented their dendrochronology work with radiocarbon "wiggle-matching," a process in which the radiocarbon profiles of the timbers are superimposed on a cal...... was available from a car battery. These microchip based sensors will use special in built heaters and can generate jumps in the sensors temperature of up to 300 degrees centigrade within milliseconds in order for it to carry out accurate analysis of a range of gases. The FIAT car company expects to hav...Virginia Tech Researchers Receive Patent For Rapid Virus Detection Technology
...liphages). "The rapid virusdetection technology is based on the fact that many viruses causesusceptible cells to break open and release their cellular contentsas a consequence of viral infection. Thus, the release of compoundsthat are normally only found within cells is indicative of thepossible presence o...Genetic Alterations Linked To Cancer In Some Blood Samples
...tient's cancer. "We decided to test serum samples based on evidence from scientists two decades ago which pointed to increased levels of serum DNA in cancer patients," Sidransky said. "More recent studies suggest that cancer cells circulating in the blood may die and release DNA, which is carried through...Human-Like Ability, Categorical Perception, Found In Insects
... is a continuum of variation between 'ba' and 'pa' based on voice onset time or VOT, which instruments can detect, our ears don't discriminate. We hear either 'ba' or 'pa' and that's how we label it. That is categorical perception, and it looked like crickets might categorically perceive sounds as either...PET Project Helps Reduce Pollution Threat From Heavy Metals
...esn't matter how bad the storm is. "Everything was based on peak flows or the heaviest flows, andwe're still getting good results," said Sansalone. The PET system is being installed along I-75 in a heavilytraveled and industrial section of Cincinnati. The UC researchershave been trapping rainwater along th...New Software Provides Quick Analysis of ion-Channel Activity
...ction, he explained. The software uses algorithms based on the work of Russian mathematician Andrey Andrey...to develop accurate models of ion-channel behavior based on the experimental data. The program says, "Give me a dataset and the models that you think apply,...Cholesterol Anchor Helps Signaling Proteins Direct Development
... that expectant mothers switch to a high-fat diet, based exclusively on these results, it might be interesting to take a look clinically at the effect of a mother's diet on the developing fetus," says Philip Beachy, Ph.D., an associate professor of molecular biology and genetics and a Howard Hughes Medical...NCAR Scientist Models Earth's Climate and Vegetation Patterns At Last Glacial Peak
... computed how much surface area each type occupied based on competition for light (related to canopy cover)...s results against earlier LGM vegetation scenarios based on data from fossilized pollen retrieved from lake cores. His simulated vegetation matched up fairly...Antarctic Science Season Gears Up With Searches for Meteorites, Neutrinos, and New Life Forms
...orting approximately 145 Antarctic investigations, based mainly out of three research stations during Antar...on the heights of the ice cap. Other projects are based at Palmer Station on the Antarctic Peninsula and on two research vessels. Antarctic research...Two Long-sought Diabetes Gene Found
...extremely prevalent disease, report research teams based at the University of Chicagos Howard Hughes Medical Institute, the Rockefeller University (New York), the University of Michigan, the Wellcome Trust Centre for Human Genetics in Oxford, England, and the Institute Pasteur de Lille, France, together wi...The CIA Would Like To Know What Scientists Are Seeing Over The Rainbow
...e to be extremely valuable in diagnosis of disease based on chromosome alterations. "The value of chromosome examination in understanding the changes that take place during disease progression could be greatly enhanced if we could study the entire genome at once, and clearly distinguish genetic material b...'BirdSource' Website For Citizen-Science Data
...ell.edu/pfw.htm . Eventually BirdSource, which is based at a national supercomputer center, the Cornell Theory Center in Ithaca, N.Y., will handle much more. "You will be able to go to BirdSource and ask, 'Where were the Dark-eyed Juncoes in December 1934?' and instantly see a map displaying reported sigh...Eating After Exertion May Be A Key To Speeding Body's Recovery
... and feelings of hunger. The pre-exercisefindings, based on human studies, were published in the American Journalof Clinical Nutrition and in the Journal of Nutrition. The post-exercise findings, involving rats, will be presented April 6-9by U. of I. graduate students Tracy Gautsch and Josh Anthony at the...