Awards honor Alt's three decades of genetic cancer research
...main in circulation and accumulate more mutations, becoming increasingly malignant. (The p53 protein is known to be mutated in almost half of human cancers, including breast, colon, lung, and prostate cancer.) When cells lacking both p53 and having defective end-joining proteins fail to repair chromosome br...Scientists discover why not enough choline results in fewer brain cells, poorer memory
... and presumably women -- especially susceptible to becoming choline deficient, the scientist said. The months before and immediately after childbirth appear to be special times when women need more in their diets. Choline is a vitamin-like substance that is sometimes treated like B vitamins and folic acid in ...'Protein-only' prions confirmed in FSU yeast study
...me "misfolded" pattern as their attackers, thereby becoming prions themselves. Invariably, this leads to the disruption or alteration of normal cell function, King said. Another key find in the FSU study is that prions formed in host cells are amyloids, a family of fiber-forming proteins that often are assoc...Preoperative treatment with Arimidex(TM) allows patients to undergo less extensive surgery
...ts use in the preoperative setting, anastrozole is becoming recognised as a potential new first-choice treatment in endocrine breast cancer therapy for postmenopausal women....Cancer rates in teens and early 20s rising
... environmental (exogenous) risk factors, which are becoming more frequent or occurring at increasing levels. Alternatively, lifestyle changes in recent years may also be contributing. For example, melanoma rates (linked to sun exposure) had almost doubled over 21 years and in the 20-24 year age group now acco...Science, policy forum focuses on 'mad cow' and related diseases
...th mad cow disease and chronic wasting disease are becoming more complex with time. Both have negative economic consequences in the United States and elsewhere," says Sharron Quisenberry, dean of Virginia Tech's College of Agriculture and Life Sciences. Maureen L. Storey, director of the Center for Food and ...Embryonic pig cell transplants halt rat diabetes
...develop into any cell type -- they are locked into becoming a particular cell type or one of a particular set of cell types that make up an organ. In multiple groups of diabetic rats that were unable to produce their own rat insulin, Hammerman and Sharon Rogers, research instructor in medicine...St. Jude/Mayo Clinic study finds direct link between CBP gene and lymphoma
...cess called apoptosis. This prevents the cell from becoming cancerous. But even though CBP is known to help activate p53, the loss of CBP in these white blood cells, called thymocytes, triggered cancer even though p53 activity appeared normal. "Given the large body of scientific literature on the subject, it...UC San Diego faculty receive funding from von Liebig Center to commercialize academic research
...essly-connected laptops, PDAs and cell phones) are becoming more popular and affordable. But delivery of wireless data to, as well as general Internet surfing on, these devices is hampered due to limited bandwidth, unpredictable error levels, and handheld constraints. Dey and his team have developed techniq...Chemical that turns mouse stem cells into heart muscles discovered by Scripps researchers
...to result in merely five percent of the stem cells becoming the desired cell type. Now Wu, Ding, Schultz, and their colleagues are working on understanding the exact biochemical mechanism whereby Cardiogenol C causes the stem cells to differentiate into cardiomyocytes, as well as attempting to improve the...Studies offer new insight into HIV vaccine development
...human immune system as the AIDS epidemic develops, becoming less and less recognizable. Watkins said that his group's findings should help allay these fears. The UW-Madison group has been studying immunity to AIDS viruses since the early 1990s. Most recently, the researchers have been studying the ways i...Neurologists create a font of human nerve cells
...only give rise to the type of neuron we want, thus becoming an ongoing source of these neurons," says Goldman, who is professor of Neurology and chief of the department's Division of Cell and Gene Therapy. Goldman's team propagated these cells for over two years, the longest anyone has ever maintained such ...Equine cloning's triple play sheds light on calcium, cell signaling, human disease
...in general." Woods began to focus on calcium after becoming interested in why horses appear to be more resistant to some forms of cancer. It is not unusual for light-colored horses to develop melanomas or skin cancers that do not metastasize. Woods found the veterinary literature was devoid of a report of a s...Studies suggest brain injury results from developmental exposure to alcohol, anesthesia, and lead
...rapidly and forming synaptic contacts required for becoming integrated into complex neural networks." The human brain goes through synaptogenesis from the sixth-month of gestation through the first few years after birth, leaving a period of several years when immature neurons would be vulnerable. Research by...Out-of-balance ecosystems play role in demise of amphibian populations
...e for more severe infections," Beasley said. "It's becoming a serious question of how we can better manage landscapes, streams, wetlands, ponds and lakes. Frogs are among the first animals that young children see in a healthy wild place, but they are not finding them in the same numbers as in past years." Ta...Human embryonic stem cells may promise medical advances
...human embryonic stem cells, potentially capable of becoming any cell in the body, from a cloned human blastocyst. The stem cells were harvested from a blastocyst produced by transferring the nucleus of a non-reproductive ("somatic") cell, containing a woman's genetic blueprint, into a nucleus-free egg from th...Asia's biodiversity vanishing into the marketplace
...al use. Even species once thought of as common are becoming rare as they are being trapped, shot or snared and sent to the marketplace. The result is loss of wildlife across the region. "In many parts of Asia, it is easier to see animals in the markets than in the forest," said COP-7 delegate Dr Kent Redford...New evidence points to pollution as main cause of much coral reef destruction
...or macroalgae, spreads over coral reefs, a problem becoming increasingly common, it can smother coral and prevent important reef inhabitants such as fish and lobster from finding the food and shelter they require. The reef that remains is transformed into a dull mound with little of its original vibrant life ...Making new muscle: Researchers in Rome produce a mouse that can regenerate its tissues
... all of the typical steps of specialisation before becoming fully integrated into the new tissue."...Inherent mistrust of research institutions limits minority representation
...tant to participate in clinical trials for fear of becoming unsuspecting test subjects for experimental drugs. The absence or under representation of such a significant racial group can be detrimental to research. Studying racial and ethnic health disparities might, for example, help unravel the role of genet...