Erodible plastic microspheres could be effective oral drug delivery system
...ven penetratelinings in the gastrointestinal tract before transferring their contents overtime into the circulation system. "The study indicates uptake of entire microspheres by specific cells,particularly absorptive cells of the small intestine," Mathiowitz said. "Thisallows us to think that a system can ...Prostate Cancer's Aggressiveness May Be Predicted Early By The Ratio Of Free To Total PSA
...stored blood samples were available up to 15 years before diagnoses for 20 men, 12 with aggressive and eight.... Since these cancers were detected late-in an era before PSA was available-the researchers could more accurately separate aggressive and non-aggressive cance...Herpes-Based Gene Therapy Is Key To Promising Liver Tumor Vaccine
...Federoffsays, and remain high for a couple of days before falling off andeventually returning to normal. The short duration and targetedscope of the high levels are key: Such high levels of cytokinesin the entire body would be toxic to most people and animals. It takes the herpes simplex viral amplicon...Herpes-Based Gene Therapy Is Key To Promising Liver Tumor Vaccine
...ederoff says, and remain high for a couple of days before falling off and eventually returning to normal. The short duration and targeted scope of the high levels are key: Such high levels of cytokines in the entire body would be toxic to most people and animals. It takes the herpes simplex viral amplicon v...Purdue Researchers Prod Plants To Clean Up Pollution
...ts generally find ways to detoxify the heavy metal before it causes damage. In research published in the journal Plant Physiology, Goldsbrough and his Australian collaborators described a mutant strain of Arabidopsis thaliana (a plant in the mustard family, often used in laboratory testing) that can't def...Duke Study Shows Early Marrow Transplant Key To 'Bubble Boy' Disease Cure
...cording to Buckley. The transplant needs tobe done before the onset of opportunistic infection, she explaine...ost disease (GVHD). By removing thedonor's T-cells before the transplant, the donor's marrow cannot rise upand attack the patient's vital organs -- a common c...Supelco Licenses ORNL Solid Sorbent Air Sampling Material
...arbon-based traps can be heated to only 400Celsius before the materials degrade. The sol-gel material, however, can beheated to 600 Celsius. Technology maturation funds from the Office of Technology Transfersupported the development and evaluation of this material. It was initiallyfunded by ORNL Laboratory ...Hot 'Lanta: NASA, School Kids Team To Study How Trees Help Cities Keep Their Cool
...e other hand, water absorbs a large amount of heat before its temperature rises 1 degree, and takes a long time torelease it. That means that trees, which have a large water content and release water into the atmosphere to keep themselvescool, also absorb a lot of the incoming heat and release it over a lon...Everyday Technology Underlies First DNA Computer Logic Gates
...odes. Ogihara says that it could be several years before the DNA logic gates are actually incorporated into a working DNA computer. In the meantime, he and Ray will explore the conditions that allow for the most accurate and efficient DNA computation. The building blocks of all today's compute...Stuttering Appears To Have Strong Link To Family Genes, Researchers Say
... children will begin to stutter at some point,most before age 5. About four of those five will stop within a few years,Yairi said. One, however, will become persistent, struggling with a disorderin which speech problems are "only the tip of the iceberg," hesaid. Finding clues as to which kids will persist -...New Evidence For Corn's Ancestry Could Lead To Insect And Drought Resistant Crops
...s about how domesticatedcorn looked many centuries before the Spanish conquest. So her research trips to Mexico and Peru aided Mangelsdorf's continuingwork. In turn, Mangelsdorf's passion quickly rubbed off on her. Eubanksbegan studying biology and performing botanical research at Duke, Indiana,North Carol...Bacterium gobbles up chlorinated pollutants
...chlorinate," Zinder said. "Then what was it doing before we invented chlorinated ethylenes?" Gossett asked. "It's true, there are some natural levels (of chlorinated ethylenes) in nature, but not in the high concentrations normally needed to support growth." The evolutionary origin of Strain 195 is just ...Ozone 'Chat Room' Provides Real-Time Air-Quality Research
...ee to the basic principles of management decisions before they are implemented. "Second, the interactive Internet approach has altered the way environmental research itself is done. Much wasted time and energy are eliminated by cutting down on travel and meetings, and fresh research is posted frequently...Summer Science: Firefly Babies Advertise Their Bitter Taste, UD Researchers Say
...gconcoction of quinine sulphate and mustard powder before being placed on theother side of the maze, which was rigged with a light-emitting diode. Thoughmice initially entered the maze "with a bias toward the glowing branch," theyquickly learned to steer clear of the bitter-tasting tidbit, UD researchers s...Two Parasitic Wasps Show Promise For Controlling Pest Flies
...andthe parasite larva feeds on the dead fly's pupa before emerging as an adultabout a month later. Spalangia endius wasps, although rare or absent in similar studiesin Kansas and Nebraska, were common in southern Illinois. Because thesewasps already are reared and sold as a biological control, mostly fo...Stopping "Cellular Suicide" Could Boost Production In Biotech Labs
...ide," Betenbaugh says. "But we canhalt thatprocess before it hits the point of no return. Instead of dyingafter twodays, our cells might live for six or seven days, makingpharmaceuticals for alonger period of time." In his initial experiments, Betenbaugh has more than doubled thelife-span of some biotech la...Fighting Wheat Scab In New York State
...with bioprotectant bacteria sprayed on wheat heads before they sprayed the wheat heads with Fusarium spores. Bio-protected plants showed fewer diseased grains with significantly lower levels of contamination by vomitoxin than did non-protected plants. Bergstrom, da Luz and Christine Stockwell, Cornell po...Gene Shears In Cutting Edge Anti-Aids Trial
...o prevent more HIV beingproduced by infected cells before it can invade healthy cells. The clinical trial uses a harmless virus as a "taxi" to insertthe ribozyme into the target CD4+ cells. The ribozyme acts by slicing upthe messenger RNA which instructs the HIV-infected cell how to make newinfectious HIV...Second Gene Responsible For Tuberous Sclerosis Complex Identified
...h insome individuals it may take considerable time before symptoms develop, TSC isknown primarily as a childhood disorder. Generally speaking, the clinicalmanifestations of TSC are the same for both genes. Seizures are the most commonsymptom. Other common features include tumors of the brain, kidneys, ey...... hay, and horse and othermanures, and is composted before use. "The compost is used for about two m...mushroom substrate must be weathered for two years before it can bereused." The mushroom industry has identified potential uses for this substrateas ...