World-first gene therapy for cystic fibrosis targets lung stem cells?
...these defences. As the cells lining the mouse nose behave in much the same way as human lung cells this enables us to use the nose airways in mice to easily develop and test out gene therapy treatments. "By instilling a single dose of a detergent found naturally in low amounts in our lungs, we are able to ...Phase transition in bilayers could affect their performance
...uticals. To better understand how these materials behave with embedded proteins, a necessary first step is to understand how the bilayers respond by themselves. As will be reported in the Dec. 9 issue of Physical Review Letters (published online Nov. 21), scientists at the University of Illinois at Urbana-...Brain's method of creating mental images differs with the source of cues received
...ect's property," said Hillis. Why would the brain behave differently when receiving information from two senses instead of one? "We rely upon our senses to tell us about the surrounding environment, including an object's size, shape and location," Hillis explained. "But sensory measurements are subject to ...Drug delivery leaps biotech hurdles
...get some of them into the body--and to get them to behave properly once they're in. Packaging and delivering proteins and other large molecules is a major hurdle. "Long a minor concern for pharmaceutical companies, drug delivery is now one very hot topic," says Technical Insights Analyst Katherine Austin. ...It may take a mouse to understand the behavior of 'jumping genes'
... chromosome retrotransposition of human L1s, which behave in exactly the same way as they do in humans. While the current tissue culture model works well, it does not mimic the way retrotransposons jump in chromosomes. The researchers believe that by understanding the mechanics of retrotransposition, they m...INEEL geoscientist to present NAPL contaminant modeling advance at AGU Meeting
...) experiments in the laboratory to study how NAPLs behave under different conditions. NAPLs can move through the vadose zone as liquid, vapor, or carried along as dissolved droplets within a moving stream of water. His experiments indicate that residual NAPL will generate pulses of contamination during heav...Animals can be induced to cooperate if partners reciprocate and benefits accumulate
...ward, then they are likely to do it." Animals that behave in reciprocal (tit-for-tat) fashion and reap rewards only after a sequence of interactions may be those most likely to cooperate in nature, said Stephens. An animal that knows it must help out in order to receive help--perhaps by group hunting or def...Chemicals used to protect soldiers in 1991 Gulf War can damage testes, animal studies show
...stingly, the chemically-treated rats don't look or behave any differently than normal rats, just as the soldiers don't show any outward signs of disease," said Abou Donia. "But under a microscope, you can see clear and well-defined damage to a variety of testicular structures." Abou Donia's team found the ...Rice University announces nanotechnology research agreement with IBM
...e had expected." Part of the reason that nanotubes behave so differently than theorists have envisioned is they are so small. At the nanometer scale, the strange and counterintuitive forces of quantum mechanics play a critical part in determining electric conductance properties. With larger wires and circui...Common pediatric anesthesia drugs cause brain damage and learning and memory problems in infant rats
...ry." The team also found that the rats appeared to behave normally in most other ways, and there were no outward signs of brain damage. "That's important because if similar brain damage had occurred in a human infant, it appears there would not be any overt signs that would alert you to it," Olney says. Thi...Fertility study shows increased estrogen shortens window of implantation in mice
...ight encounter, such as some pesticides, which can behave as estrogens. And, there may be ethnic or population differences, based on genetics, which influence sensitivity to estrogen. Such factors could contribute toward implantation failures generally, even among those couples not participating in assisted...Michigan researcher helps resolve the conflict between exotic birds and eco-tourists
...irds, their importance to the community and how to behave so as not to disturb them. "The tourists really appreciate the new amenities," Bouton says. "Now there's a little shop to buy cool drinks, an orientation talk that tells them what to look for and well-informed guides to accompany them on the trail. T...Genetics may help solve mysteries of human evolution
...ppened. ''Suddenly, modern-looking people began to behave in a modern way, in producing art and jewelry and ...nt ethnic groups. Why did people suddenly begin to behave in a more modern fashion? This question has been a source of discord among many anthropologists. Som...Sex and gender scientists explore a revolution in evolution
... cleaning wrasse, the largest female will start to behave like a male within hours. Within 10 days she - now he - will produce sperm. Behavior is not tied to one's chromosomes, either - many species have three or more genders. For instance, bluegill sunfish have two different male genders - ''parental'' mal...Mutants from a lowly weed may solve maladies
...re must be a reason that the additional regulators behave differently." He said future research may lead to transferring the phenomena in plants in vitro or in transgenic plants to see if any of the four plant CTDs are more sensitive or more resistant to the HIV protein known as TAT....DuPont technology to receive US EPA's clean air excellence award
...each other. Simply stated, the solids are made to behave more like a fluid, without requiring higher levels of solvent. SuperSolids TM make it possible to use existing liquid paint equipment without additional hardware costs for applying the paint and add-on emissions equipment, generating potential cos...Scientists' transgenic chicken aids embryo research
...chers say learning the mechanisms behind how cells behave during embryo development could eventually provide...r another transgenic chicken and see how the cells behave and interact with each other." "This tool provides the impetus to go to the next level of looking at...... nanostructure scale, materials and structures can behave completely differently at small scale than they do...ven the most basic assumptions about how materials behave will need to be rethought. "When we model things at the large scale we tend to ignore some effects a...Inactive genes may contribute to failure of animals cloned from adult cells, study finds
...y whittled the larger set of genes down to 10 that behave similarly to Oct4. A team of scientists at Whitehead Institute and the University of Hawaii cloned two types of mouse embryos: one derived from embryonic stem cells and another from somatic cells. Scrutiny of the clones' genetic activity revealed t......y and placed into an artificial medium, where they behave differently than in their natural environment, a little like trying to study a fish out of water. Secondly, the other studies involved cells from tissue sections, which literally provide scientists with only part of the picture. "What happens with...