Transparent fish provide window on blood formation and marrow transplantation
...visualize how the transplanted cells will actually behave when they're put back into easily visualized animal," said Zon. "We believe that this ability to be highly selective about which populations of blood cells we're analyzing constitutes a tremendous advance for the field." Zon and his colleagues next u...Naked mole-rats bare pain relief clues
...his single chemical could make the naked mole-rats behave just like other mammals." Further experiments are planned with the rats to investigate how other pain systems work in the absence of Substance P....Gliomas' 'molecular fingerprint' predicts how aggressive tumor will be
...vidual's tumor, scientifically predict how it will behave and use that information to tailor treatment decis...complete picture of how their tumor is expected to behave and how it is expected to respond to treatment," Caprioli said. "Then they an their doctors can make...Proteins may help identify patients who will respond better to treatments in certain cancers
...vidual's tumor, scientifically predict how it will behave and use that information to tailor treatment decisions." Each year, about 25,000 new gliomas are diagnosed, about half of which are particularly vicious, with a median survival of one year with aggressive therapy. Currently, diagnostic techniques do ...Taming Jaws: Scientists lift great white sharks from ocean to fit with satellite tags
... said WCS researcher Dr. Ramn Bonfil. "Our sharks behave like tamed kittens once in the cradle, hardly ever moving or noticing that we are working on them like the pit-crew of a F1 racing car. Then they swim away strongly upon release". According to Bonfil, the sharks spend only three to seven minutes out...Researchers identify molecular cause of drug-resistant prostate cancer
... in hormone-refractory cells, those cells began to behave like hormone-sensitive cells. They also established that the over-expressed hormone receptor still required binding by the ligand androgen in order to become hormone-refractory. "This finding is perhaps the most important," said Sawyers. "Everyone, ...Researchers seek to clone 'mad cow disease' resistant cattle strain
...nside a cell or elsewhere in the body. But prions behave very differently than these more common disease-causing organisms, explains Eyestone. Prions are actually a form of protein that naturally occur in all mammals, though scientists remain uncertain about the exact purpose they serve in advanced mammals...A possible new form of 'supersolid' matter
...y take over. In effect, the helium atoms start to behave as if they were both solid and fluid--at the same time. Under the right circumstances, in fact, some fraction of the helium atoms can begin to move through the lattice like a substance known as a "superfluid": a liquid that moves with no friction wh...Understanding urinary tract infections
...to replicate inside their target cell, they almost behave more like a multicellular organism," Hultgren expl...d instead of acting like individual bacteria, they behave more in a multicellular manner, working together to defeat the cell's defenses." Hultgren and his co...Fat cells fight disease, Purdue University researchers find
...onse. "This is additional evidence that fat cells behave in many ways as immune cells," Spurlock said. "It also is the first evidence that adipocyte cells respond directly to bacterial toxins like classical immune cells." To produce this infection-fighting response, Ajuwon, a doctoral student, performed ...European researchers launch 10 million euro collaborative technology project
... for instance the way proteins and other molecules behave in cells, or to design new drugs that will affect their functions. The most common method for obtaining such three-dimensional models is to bombard crystallised proteins with high-powered X-rays generated at huge synchrotron facilities. "We already ...Small amounts of alcohol or anesthetics may damage the developing brain
...ptation to new environments. The rats appeared to behave normally in most other ways, and there were no outward signs of brain damage. "If similar brain damage had occurred in a human infant, it appears there would not be any overt signs that would alert you to it," Zorumski says. This area of research h...Most clones doomed from the start, according to Temple University embryologist
...ormation. Consequently, cloned embryos develop and behave as a hybrid somewhere between an embryo and the adult organism from which it has been cloned. "Until we learn how to improve the reprogramming of cloned embryos and how to help them transition into a normal, healthy embryo, cloning will remain marg...UNC study may improve gene therapy safety
...ss in understanding how viral gene therapy vectors behave in laboratory animals, in terms of acute toxicity effects. However, they wrote, "systematic comparison of their effects upon cells at the molecular level has not been established." In that regard, the new research offers important new and potentially...Tagging faulty genes with fluorescent nanodots
...hough they contain hundreds to thousands of atoms, behave like single atoms electronically. Quantum dots absorb light efficiently over a wide frequency range and re-emit it at a single wavelength (or color) that depends on particle size....Researchers model embryo implantation and tumour metastasis in fruit flies
...e process and must be regulated so that it doesn't behave like a metastatic tumour," said Dr. Reed. "The implication is that there is a fine balance between the good kind of invasion and the bad kind." In mammals, basigin is expressed on the surface of 60 per cent of human gliomas, a type of nervous system ...New, comprehensive tumor classification combines molecular biology and classic pathology
...eristics of those cells determine how a tumor will behave information of great importance to clinicians. Berman has organized his classification using these two features. At the highest level of the classification, tumors are grouped according to the component cells' developmental history their 'histogene...New toxicity test could cut animal testing
...er their patterns of gene expression and no longer behave like liver cells in vivo. For example they often lose the ability to produce drug-activating and modifying enzymes. Cultured MMH-GH cell lines do not suffer from this problem, retaining features of liver cells inside the mouse. Moreover, if important...Scientists discover that metastases share a similar genetic profile to their primary tumour
...tradicted the notion that breast cancer metastases behave differently to their primary tumours. PhD student, Britta Weigelt told the meeting of the 4th European Breast Cancer Conference today (Thursday 18 March) that, contrary to what had been thought previously, any primary breast cancer cell was capable o......ghly predictive indicator of how these drugs would behave in people. Kuperwasser is currently consulting with pharmaceutical companies who are developing breast cancer therapies. Meanwhile, Whitehead has filed a patent for this procedure. The next step is to take advanced human breast cancer tissues from p...