Cancer vaccine based on pathogenic listeria bacteria shows promise targeting metastases
...within the body of the cell. The bacteria would be benign if they remained isolated in this compartment, because the cell can kill them there. But they are able to break out into the cell interior, the cytosol, and take over the host cell's machinery to spread the infection. Once hooked into the cell's mach...Study: Emission of smog ingredients from trees is increasing rapidly
...on the environment, because something as seemingly benign as planting forests can have a substantial impact. "You can't identify any of these processes as 'natural,'" said Purves. "The idea of natural versus human-caused is disappearing. Ten years from now, woodlands may have more of one species than anoth...Researchers identify distinctive signature for metastatic prostate cancer
... that are likely to spread from those that remain benign and localized to the prostate. Prostate cancer is...of Hedgehog activity in these tissues, compared to benign prostate tissue samples. The researchers also found high levels of Hedgehog pathway activity in rat ...Missing genes may help explain why plague bacteria are so deadly
...sibly giving it an evolutionary leg up on its more benign cousins. Evolutionary pressures may have also made the bacterium better adapted to colonize the flea, its preferred vector (means of transmission), and thus facilitate the flea-borne spread of the disease. Perhaps the most infectious of all bacteria...Study reveals first genetic step necessary for prostate cancer growth
...genes - that must collaborate with Rb to drive the benign condition to cancer. Ideally, blood or other simple tests to detect these mutations could be developed that reveal predictive information about a man's type of cancer well before he is in danger. "The idea is to set the bar for detection as early as ...OHSU-VAMC study sheds light on estrogen's benefit for MS
...ment. "This is the first report that this single, benign compound estrogen can increase regulatory cells," said study co-author Halina Offner, Ph.D., professor of neurology, and anesthesiology and peri-operative medicine, OHSU School of Medicine and the Portland VA Medical Center. "When you remove (the C...Bright idea could doom cancer and viruses, say Purdue scientists
...therapy drugs, but with one exception - it remains benign until irradiated with a light beam. "Anticancer therapies could, in theory, be developed using such photo-activated rhodium complexes," Morrison said. "The interior of the body is dark, but it might be possible to thread a fiberoptic cable through t...Regular physical activity really does boost immune system in older men
...ults, they used KLH (keyhole limpet hemocyanin), a benign T cell-dependent protein isolate that has been used extensively with animals in the past, that also is safe for humans. The study, entitled "Influence of age and physical activity on the primary in vivo antibody and T cell-mediated responses in men,"...Hopkins scientists use blood proteins to detect ovarian cancer
...cancer patients, healthy people, and patients with benign ovarian tumors. A sophisticated bioinformatics program was used to select proteins present at unusually high or low levels in ovarian cancer samples as compared with normal or benign. Samples in the two groups were analyzed separately to account f...UC Riverside researcher takes snapshots of the movement of molecules in a billionth of a second
... catalyst surface can transform the pollutant into benign gasses while the rest of the surface supports these active sites. Understanding how carbon monoxide moves across a catalyst surface to find the active sites may ultimately allow the design of more efficient catalysts. The article's findings offer a n...Duke study disputes idea that trees can 'relocate' quickly in response to climate change
... said his team's findings suggest there was a more benign local environment. "It means the trees were much closer to the ice than we thought. Maybe there weren't the really severe winters there we traditionally think of. It could be that the climate of that time is something we don't fully understand yet." ...Ancient life form may help create newest technologies
...nexpensively, through the natural, environmentally benign process of biomineralization. Most solid-state electronic devices consist of patterned arrays of metal or metal-oxide semiconductor materials based on silicon, germanium and other materials. The technologies for making those devices on the micron si......paper. Scientists are increasingly turning to more benign natural chemicals to ward off mosquitoes and other pests. Chang and his coworkers tested eleven compounds in cinnamon leaf oil for their ability to kill emerging larvae of the yellow fever mosquito, Aedes aegypti . "Four compounds cinnamaldehyde, c...Gene expression patterns may help predict risk and progression of prostate cancer
...e Journal of Clinical Oncology, genes expressed in benign tissue adjacent to prostate cancer tissue are much...6 samples of prostate cancer tissue, 60 samples of benign prostate tissue adjacent to the tumor, 23 samples of donor prostate tissue free of genitourinary dis...Croatian skeletons reveal changing status of cancer in Europe across the centuries
...the specimens is 35.6 years. Primary malignant and benign tumours of bone are relatively rare, even in young individuals where the incidence of these neoplasms is highest, whilst secondary tumours of bone, although much more common, are associated with older age". Life expectancy in the 21st Century is hig...Chemical Society announces EPA awards for environmentally friendly technology
...ure and pressure, these researchers create tunable benign solvents from water and carbon dioxide (CO 2 ), wh...t polyvinyl acetate and transform it into a more benign polyvinyl alcohol. Engineered by bacteria, a renewable resource, the enzyme represents a safe, biode...$5 million grant funds partnership, studies of minority-based issues in reproductive health
...ng higher prevalence of polycystic ovary syndrome, benign tumors, and contribute to gynecological cancers. While the increased steroids pose some risks, they also seem to provide protection from osteoporosis. "The mechanisms explaining racial differences in these diseases are poorly understood and this cent...Harmless virus helps slow HIV by boosting immune proteins
...ght yet into the biological mechanisms of GBV-C, a benign cousin of the hepatitis C virus. The virus infects almost all HIV patients at some point in their illness, but seems to cause no harm by itself. When present over several years, the virus appears to slow HIV growth and keep patients from developing f...Other Highlights in the June 2 JNCI
...he test has a high rate of false positives because benign diseases, such as prostate enlargement, can increase PSA levels. AMACR expression has been shown to be increased in prostate cancers, but AMACR levels in blood are too low to be detected. To determine whether an immune response to AMACR could be used...A new way to kill cancer: SLU research shows viruses can destroy lung, colon tumors
...hing for many years ways to convert the relatively benign "adenovirus" that causes symptoms similar to the common cold in children into an anti-cancer drug that attacks and destroys cancerous cells. Wold's group has developed several new "adenovirus cancer gene therapy vectors," changing these genes so th...