Getting a handle on sensitive cycles
...esult is the same, but the sequence of events is a bit different," Reid says. "The active receptor summons other molecules to read the information in the DNA and transcribe it into RNA. After accomplishing this, they, too, become loaded with ubiquitin. Again, this leads to their removal from the gene. Wh......f the unqualified promises of stem cell research a bit exaggerated. Nevertheless, stem cell research does have real potential to improve several important aspects of our lives, something that even opponents of the research acknowledge. To many people, this potential is sufficient justification to pursue ...VEGF gene transfer fails to help peripheral arterial disease patients
...aluation of results. "The public has heard quite a bit about these approaches in the years since the media reported first signs of success from pilot-phase and Phase I studies," says Rajagopalan. "It's important that we did these scientific Phase II studies so that we could learn more about safety and al...Scientists identify protein channel that mediates body's ability to feel frigid temperatures
...unicated to the brain. Biochemically, ANKTM1 is a bit of a puzzle because proteins are normally more active at higher temperatures. Even more bizarre is the fact that these cold-sensing ANKTM1 proteins are coexpressed with their cousins, the hot-sensing TRPV1 proteins on the same neurons. This means tha......ble that this microbe naturally inhabits corals, a bit like Escherichia coli in the human gut, and temperature increases cause it to trigger bleaching," he says....Research shows cocaine 'reward' picture more complicated than scientists thought
...archers believed. It also brings medical science a bit closer to the day when effective therapies will be available to treat cocaine addiction, the scientists say. Dr. Linda Dyksta, William Rand Kenan Jr. professor of psychology and pharmacology and dean of the graduate school at UNC, presented the team'...An unexplored genomic terrain in a handful of dirt
...logies of these newly isolated phages were quite a bit more varied than we had imagined. These surprising findings should give us new information about the relationship between genomic information and viral morphologies." Hatfull's team turned up some interesting information when comparing the genomes of...Microgel polymer beads may provide general vehicle for vaccines, gene therapy
...acidic digestive chambers.) Making the beads is a bit like making latex paint by suspension polymerization, he said. Mix the polymer chemicals with the protein antigens in a solvent - in this case, hexane - and the water loving chemicals form tiny spheres, just as oil forms globules in water. The polyme...Purdue biologists crystallize technique to expand protein research
... the protein in a synthetic detergent and adding a bit of synthetic fat as 'glue,' we have produced cryst...d to the Germans' technique. So we needed a little bit of 'glue' to keep a protein organized even in solution." To solve the problem, Cramer's team ended u...Secrets of drug resistance in bacteria
... needed to fight the infection. "The protein is a bit too efficient for our own good," McDermott says. "And our work demonstrates why. We suspect the protein's cavity possesses areas where many types of antibiotics could be captured." Their research also underscores the need to pursue alternative ways o...Body clocks keep migrating monarchs on course, Science study shows
...ock and a compass. This makes monarch navigation a bit simpler than navigation in foraging insects where each new route has to be learned," Reppert said. Understanding how the circadian clock assists the sun compass in the relatively simple navigation by monarchs could provide a model for studying naviga...NHGRI study may help scientists develop safer methods for gene therapy
...tion site by capturing and then sequencing a small bit of the human genome immediately adjacent to where the retrovirus inserted. "Now that a high-quality, finished copy of the human genome is available in public databases, it only takes the sequence of 30 base pairs (the chemical subunits that make up ...'Unzipping' double helix to study protein-DNA interaction
...ips as soon as tension is relaxed so that the same bit of DNA can be recycled again and again with numerous proteins. After working on the technique for nearly three years, Wang has applied for a patent through the Cornell Research Foundation. Among other possible applications of UFAPA, she says, are t...Diet researcher asks how now lemur chow?
...s for these exotic animals "Now, we know a little bit about their dietary efficiency and how they process fiber," she said. "We don't know a lot about their vitamin or mineral requirements, or the optimum levels of dietary protein." Campbell said she would like to continue such studies as a zoo nutritio...Counting the molecules that pull cells apart
...ce displayed an intriguing feature, which, after a bit of mathematical exercise, showed the researchers that there are more motors pulling on the posterior aster: about 25, compare to roughly 15 on the other side. Even though a small number of motors are involved, that's enough to pull the centrosome off...Rising ozone levels pose challenge to U.S. soybean production, scientists say
...rowing season. "What we found was surprising and a bit shocking -- with a 20 percent rise in ozone exposure we also saw a 20 percent drop in yield," said Stephen P. Long, a professor in the departments of plant biology and crop sciences at Illinois and Morgan's doctoral adviser. "Ozone levels are already...Popular Science announces second annual 'Brilliant 10:' the country's top young scientists
...ey also work as computers. Recently, he unveiled a bit made of liquids. His new chips possess thousands more channels than their silicon forebears, and they keep getting smaller. Sarah Tishkoff, 37, University of Maryland, College Park, for her work in the field of molecular anthropology. Tishkoff real...Carnegie Mellon researchers developing new ways to store tissue, organs
...t transfer in biological systems. "It is a little bit like watching an ice cube break up in a glass of water and trying to figure out what made the ice fracture and devise ways to prevent it from cracking," Rabin said. Both Rabin and Steif are charged with developing engineering tools to monitor when t...Researchers one step closer to Holy Grail of neurobiology
... aroused anyway, whereas if I'm asleep, I'm just a bit sluggish in my response." To understand how changes in the expression of specific genes can influence arousal, the scientists studied changes in arousal of two different types of genetically altered mice: one mouse lacked the gene for the estrogen re...Brain links non-food images with eating -- But only when hungry, study suggests
...steak we dashed for the door, it would be a little bit impractical," he said. A faulty brake system seems to be at least part of the problem for patients with Kluver-Bucy syndrome, who often consume huge amounts of food, even putting non-food items in their mouth. These patients have damage to brain regi...