Cigarette smoke causes breaks in DNA and defects to a cell's chromosomes, Pitt study finds
...cigarette smoking is linked to oral, larynx, lung, bladder and esophageal cancers, our results showing that cigarette smoke can produce anaphase bridges and destabilize a cell's chromosomes have added significance," said Dr. Saunders. "The failure of the cell to accurately repair the cigarette smoke condensa...U-M scientists find common virus in human prostate tissue
...transplant the virus can cause serious kidney and bladder disease. Now, new research by scientists at the University of Michigan Medical School suggests the intriguing possibility that this common virus also may play a role in prostate cancer the second-leading cause of deaths from cancer in American ...Newly grown kidneys can sustain life in rats
...lant, researchers connected the new kidneys to the bladder and administered a second dose of growth factors. ...g life, scientists cut the connections between the bladder and the new kidneys in a subset of the experimental rats. Rats with no new kidneys lived for two to ...Research finds lawn chemicals raise cancer risk in Scottish terriers
...de-treated lawns and gardens increases the risk of bladder cancer in Scottish terriers, a discovery that coul...risk of transitional cell carcinoma of the urinary bladder in Scottish terriers and the dogs' exposure to chemicals found in lawn treatments. The study, based ...'Meeting of the minds' leads new era in fight against cancer
...al cancer risk; vitamin E lowers risk of prostate, bladder cancers; tobacco-induced genetic changes may be targets for intervention, prevention; new diagnostic tools from proteomics to fight ovarian cancer; the effect of sun on cancer prevention, immune response. Symposia and Forums: covering a diverse ...UT Southwestern researchers identify gene as essential for vascular smooth muscle development
...ny internal organs such as the stomach, intestine, bladder and uterus. Abnormalities in their growth can cause a wide range of human disorders, including atherosclerosis, hypertension, asthma and leiomyosarcoma (a fatal smooth-muscle cancer). The molecular mechanisms that control smooth muscle cell growth an...Other highlights in the March 3 issue of JNCI
... survivors were more likely to die of lung cancer, bladder cancer, and all other epithelial cancers combined. Contact: Lindsay Wright, London School of Hygiene and Tropical Medicine, 207-927-2073, Lindsay.Wright@lshtm.ac.uk Dietary Folate Intake May Be Associated With Reduced Risk of Ovarian Cancer A h...Just how much water do we really need? The answer may depend on our age
...ectal cancer, premalignant adenomatous polyps, and bladder cancer. Water deprivation results in life-threatening dehydration within a few days. Loss of body water exceeding five percent of body weight leads to decreased endurance, culminating in heat exhaustion. Older vs. younger individuals have been show...Bacteria lingering in body may pose future food poisoning risks, Stanford study finds
...escape the immune system by hiding out in the gall bladder of seemingly healthy people. The finding by resear...ave discovered a chronic carrier state in the gall bladder of an animal model, suggesting a potential source of food contamination, is important," said senior ...Understanding urinary tract infections
...state, creating reservoirs of infection within the bladder that might be responsible for some of the recurren...nteractions with each other to collectively hijack bladder cells and use them as safe havens for replication. "It just boggles the mind what these bacteria can...Social stress adversely affects digestive function in subordinate cichlid fish
...orehouse College, compared bile retention and gall bladder size in dominant and subordinate males that had ea... bile in the dominant fish. The difference in gall bladder function also likely contributed to subordinate fish growing more slowly than the dominant ones.Cich...Vegetables that prevent may ultimately cure some cancers
...pounds also inhibited growth of pancreatic, colon, bladder and ovarian cancer cells in culture, Safe said. Limited trials on lab mice and rats have produced the similar results, he noted. Safe said the research began by considering compounds that protect a person from developing cancer. Journal articles of...Other highlights in the December 17 issue of JNCI
...ain genetic stability, are frequently defective in bladder cancer cell lines, a new study has found. Compared with normal human uroepithelial cells, bladder cancer cell lines had severely attenuated checkpoint function, report Sharon C. Doherty, Ph.D., of t...New drug target and biomarker for advanced childhood cancer discovered
...monly overexpressed in breast, colon, pancreas and bladder tumors and correlated with poor prognosis for these diseases -- are important in regulating mitosis and the process of cell division. Because they are only expressed in cells that are actively dividing, these kinases could be an important new target ...New treatment to beat severe incontinence
...the patient's own body and transplanting it to the bladder where it acts as a replacement sphincter. One of the causes of the most common type of urinary incontinence, known as stress incontinence, is when the sphincter muscle no longer dependably keeps urine in the bladder. The replacement sphincter is con...NIH funds 'Breast Cancer and the Environmental Research Center' at Fox Chase Cancer Center
...of certain industrial chemicals has helped prevent bladder and other cancers. If we can also find environmental causes for breast cancer, we will be on our way to preventing many of these cases." Jose Russo concluded, "I am confident that the knowledge created through these studies will enrich us intellectu...New gene for rare inherited paralysis may aid other spinal cord research, too
...uscle movements, and medication to treat patients' bladder and bowel control problems, and depression. "There are direct overlaps between this group of diseases and the nerve degeneration processes in other disorders," says senior author John Fink, M.D., professor of neurology at the University of Michigan ...Grant funds research to develop tissue-engineered solutions for heart disease
...e other "mechanically active tissues," such as the bladder and urethra, said Dr. Wagner, adding that researchers hope to be close to the brink of clinical trials in terms of refining techniques at the close of the five-year grant period. "This work is a fine example of the unique synergy among research disci...Key step allowing cell migration
...riments were done on both fish scale cells and rat bladder tumor cells. They identify a specific biochemical pathway by which signals from outside cells--provided by hormones and growth factors--can regulate cell locomotion, he said.Understanding the complex cascade of molecular events could become a key to ...Sleep disorders linked to faulty brain chemistry, study finds
...blood pressure, muscle tone and movement, balance, bladder control and sleep. Patients experience debilitating and rapidly progressing symptoms, usually dying within seven to 10 years of diagnosis. In addition to plaguing MSA patients, sleep disorders are also a fact of life for millions of others. Obstruc...