Strep disrupts blood clotting to infect humans
...ia use an enzyme called streptokinase to block the blood clotting response and allow themselves to move mor...to grow, the clotting system produces clots in the blood vessels around the infection, closing the highways that the bacteria would use to spread," said Davi...Integrative biology of exercise APS Intersociety meeting October 6-9, 2004 in Austin
...renda Russell. Altered cardiovascular control and blood flow to exercising muscles. Chair Michael J. Joyner. Mechanical forces and signal transduction in vascular remodeling. Chair Steven S. Segal. Cytokines, muscle and metabolism. Chair -- Pope Moseley and Bente Klarlund Pedersen. Design of muscle ...Review article makes case for a new source of cells in the body
...ncluding the gastrointestinal tract, heart, liver, blood vessels, inner ear and skull. "There aren't a huge number of them in most tissues," says Dr. Dickinson. "But what is exciting about VENT cells is that if you interfere with VENT cells arriving at those target tissues, you appear to cause major disrup...UC Irvine scientists to develop vaccine to combat bioterrorism threat from deadly bacteria
...t contact with contaminated soil. Contact with the blood or body fluids of an infected person also can spread the disease. Symptoms of melioidosis include fever, anorexia, muscle aches and chest pain. The disease can result in pulmonary infections ranging from mild bronchitis to severe pneumonia. Some pat...Bright idea could doom cancer and viruses, say Purdue scientists
... could have potential as anticancer agents and for blood sterilization. "We have proven in principle that l...ul to a patient's body and guarantee safe, sterile blood for transfusions." The research, which appears in the current (Aug. 23) issue of Inorganic Chemistry...Tiny molecules have big potential as cancer drugs, Stanford researcher believes
... of cancer. They found the cathepsins helped build blood vessels to the tumors as well as increase tumor gr...ent cancers and are involved in processes such as blood vessel formation and tumor growth critical to all tumors. "It suggests that anything that's aggress...Marathoning mice could have Olympian effects on obesity
...and other disorders of fat metabolism such as high blood cholesterol. This experiment underscores the importance of metabolism in fighting obesity and improving fitness, said Evans. Activating the PPAR switch may prevent physical fatigue and enhance the quality of exercise, which may lead to a new class o...Regular physical activity really does boost immune system in older men
...stage, all subjects were "immunized" with KLH with blood collected on day one and then each week for a month. The samples were comprehensively tested by ELISA (enzyme-linked immunoabsorbent assay) for anti-KLH IgM, IgG, IgG1 and IgG2. The second phase was three weeks later. Subjects received an intradermal...Two warbler species find the West isn't big enough for both of them
...Once the birds were captured, the researchers drew blood from veins in the wings, then placed it on ice until they could use a centrifuge to separate the plasma, done within six hours. The plasma was stored at minus-20 degrees Celsius to preserve the hormones until it could be returned to the UW for analys...UCSD biologists develop 'super-endurance' strain of mice
...ed that "knocking out" the HIF-1 gene in the white blood cells of mice limited the tendency of the cells to rush en masse to areas of infection, a primary cause of inflammation. By limiting the cells' ability to guide themselves with the HIF-1 protein to the sites of infection by honing in on the low oxyge...Engineering endurance: The future of the Olympics?
...now the "lactic acid burn" associated with reduced blood pH.) Glycolysis--the primary source of anaerobic e... as glycogen in muscle cells, to produce ATP. When blood oxygen levels drop, the gene transcription factor hypoxia-inducible factor 1 (HIF-1) triggers the gl...Nevada researcher re-ignites mammal reproduction debate
...t could all boil down to the amount of glucose, or blood sugar, in a female mammal's body around the time of conception, Cameron said. She conducted an analysis of 1,000 studies that examined the Trivers-Willard hypothesis and sex ratios in mammals. Her study found that female mammals that were in better...Breakthrough in understanding of hereditary disease of lymphatic vessels
...s normally remove fluid and proteins escaping from blood capillaries into surrounding tissues, and lymphede...ooth muscle cells that are usually present only on blood vessels and on larger, collecting lymphatic vessels. In addition, mutations in Foxc2 led to a lack o...New compound could give some types of cancer the one-two punch
... also prevented angiogenesis the formation of new blood vessels from pre-existing ones," said Tom Li, the ...OSU 111 also prevents tumor cells from forming new blood vessels. Scientists are looking for alternatives to established anti-cancer drugs, such as Taxol, wh...Penn scientists identify novel pathway in aneurysms
...reted by inflammatory cells that gather at injured blood vessels. Abdominal aortic aneurysms are a bulging ...enzyme mainly in macrophages in the outer layer of blood vessels not in the fatty atherosclerotic lesions of the inner layer, as expected. (Macrophages engul...U of T study identifies possible stem cells in pancreas
...cells, release insulin to help regulate the body's blood sugar levels. "People have been intensely searching for pancreatic stem cells for a while now, and so our discovery of precursor cells within the adult pancreas that are capable of making new pancreatic cells is very exciting," says Simon Smukler, a ...Study suggests cell-cycle triggers might be cancer drug targets
..."It's not known whether D cyclins are required for blood cell generation in adults," said Sicinski. "We are addressing this in ongoing experiments." The blood system issue aside, the results remove a major theoretical objection to developing drugs that would ...Researchers report new gene test for isolated cleft lip and palate
... we've reached a point where it's possible to take blood samples from parents, test certain genes, and determine whether their risk for a second child with cleft lip or palate is, say, 1 or 20 percent," said Jeffrey Murray, M. D., a scientist at the University of Iowa and the senior author on the study. "...Nucleic acid-amplification testing further safeguards nation's blood supply
State-of-the-art testing systems to screen donated blood have improved the safety of the nation's blood supply by preventing the transmission of potentially deadly viruses, according to a new study funded...MIT research that stops pain of needle jabs gets FDA approval
...ices that sense the level of sugar in a diabetic's blood and/or deliver insulin or other medication to the blood. The scientists believe that the same mechanism can be used to deliver routine vaccinations painlessly within the next five years....