Viral proteins may prevent bacterial infections
...the enzyme will eliminate enough bacteria from the blood after anthrax exposure to extend the window of time during which antibiotic therapy will be effective. ...Fundamental change to Immunology 101
...m cells (HSCs) are the ultimate progenitors of all blood cell types, from platelets and red blood cells (erythrocytes) to immune cells like T cells and B cells. But T-cell development differs from o...UCSD researchers are first to demonstrate molecular link between inflammation and cancer
...tant role in the immune system by generating white blood cells called macrophages to induce inflammation and fight infection. Focusing on the epithelial cells deficient in IKK beta, the researchers found that DSS induced inflammation in the mice, even without NF-kB activation. And yet, the incidence of t...Molecular therapeutics advance fight against brain cancer
...y with a three-dimensional map of tumor-associated blood flow to more precisely assess the full extent of t...n addition, there is no requirement for additional blood samples, so results will be given more quickly with no need for follow-up visits. Penn colleagues J...Depression traced to overactive brain circuit
...o acids washes out the precursor chemical from the blood and brain, depleting serotonin and often triggerin...r. The researchers scanned subjects after their blood tryptophan levels were reduced by about three-fourths, using a radioactive tracer (a form of glucose...Education, monitoring vital for sport-fish eaters
... and sport-fish eaters to ascertain how high their blood mercury levels were in relation to the amount of f...how that 87 per cent of the anglers had detectable blood mercury levels, all within Health Canada's acceptable range. The consumers all had detectable blood ...Babies with DiGeorge syndrome saved by immune supression, thymus transplant
...e, where it is most likely to develop a network of blood vessels to deliver nourishment and oxygen. After transplantation, immature white blood cells from the baby's bone marrow migrate to the thymus tissue, where they are trained to differenti...Commercialization deal boosts hope for new sickle-cell drug
...options are few for sickle-cell disease, a genetic blood disorder that affects millions of children and adu...90s that clotrimazole also reduces sickling of red blood cells. In sickle cell disease, the body produces an abnormal form of hemoglobin, the compound ...JCI table of contents, 2 August, 2004
.... The authors isolated CD34+ cells from human cord blood and injected them into mice within 48 hours of a stroke. These mice experienced increase new blood vessel growth in stoke-damaged region. The CD34+ cells also produced growth factors to aid in neura...... The authors isolated CD34+ cells from human cord blood and injected them into mice within 48 hours of a stroke. These mice experienced increase new blood vessel growth in stoke-damaged region. The CD34+ cells also produced growth factors to aid in neura...Genetic discovery could dramatically reduce need for liver transplants in children
...control inflammation) secreted by disease-fighting blood cells in the origin and development of the disease. In other words, infants with biliary atresia are prone to develop an inflammatory response against themselves, according to Dr. Bezerra. The study suggests that these inflammatory cells see the bili...'Smart gene therapy' protects against damage from heart attack
...to the oxygen deprivation that follows the reduced blood flow, or ischemia, from coronary artery disease an...dition in which tissues are susceptible to loss of blood supply, including stroke, shock, trauma and sepsis, the researchers said. When administered to rat h...Two enzymes key to calorie-burning, Brown research shows
.... These include insulin, the hormone that controls blood sugar. This finding will aid in the understanding and treatment of obesity, which affects nearly 68 million adults, teen-agers and children in the United States. "What we have is an important discovery of how leptin regulates specific enzymes," Nilln......tarved, and thus had low levels of leptin in their blood serum levels also had lower levels of these two enzymes. Consistent with the lower levels of the enzymes, these fasted rats likewise did not have a significant amount of the active (cleaved form) of thyrotopin-releasing hormone. Giving leptin directl......and fat cells become resistant to insulin, causing blood glucose levels to rise and eventually damage nerves and blood vessels. Dr. Roger Davis and colleagues in the Howard Hughes Medical Institute at UMASS Medical Sch...Blood pressure hormone may inhibit growth of lung cancer
....C. A hormone that is important in the control of blood pressure may also inhibit the growth of lung cance...1988, and found it to be a critical element of the blood pressure control system. Angiotensin-(1-7) relaxes (dilates) the walls of the blood vessels, causin...New glycan arrays discover autoimmunogenic activities of SARS-CoV: concern over monkey vaccine
...e structures on an array, they especially included blood group substances A, B, O, Lewis, I, and i antigens, their precursors and structural derivatives that were fostered by the late Columbia Professor Elvin A. Kabat and others. Wang and Lu believed that scanning the antibody "fingerprints" of immunized ...UNC researchers awarded $8.65 million from National Institute on Aging
...8.65 million to investigate the molecular basis of blood vessel aging and its role in the development of vascular disease, including heart attack. The five-year grant comes from the National Institute on Aging, a component of the National Institutes of Health.New information gleaned from this basic r...Scientists build on case connecting inflammatory disease and depression
...ncer patients treated with cytokines had decreased blood levels of tryptophan. As tryptophan levels decreased, the severity of depression increased. That finding compelled Dantzer and Kelley to study how cytokines induce depression. "We have always known that behavioral changes accompany sickness," Kelle...Misfiring proteins tied to inflammation and sick feeling of type 2 diabetics
...ired when they tested macrophages (a type of white blood cells) removed from type 2 diabetic mice. The find...lab. Vanadyl sulfate, which now is used to reduce blood sugar content, improves insulin signaling and insulin-dependent glucose uptake in skeletal muscle in...