Novel, even unlikely drugs may curb childhood leukemia
...occurring protein interleukin-2 may kick-start the bodys immune system to better fight leukemia. Taming c...e "graft vs. leukemia effect," IL-2 stimulates the bodys natural killer cells to attack leukemia cells and drive the disease into remission. The pediatric......ells (HTLs). Together, CTLs and HTLs comprise the bodys natural defense against HIV in which CTLs are capable of directly destroying virus-infected cells but require HTLs, which produce immune-boosting chemicals, for proper functioning. Epimmune has designed its vaccine to provide immunity against many ...Mechanism for generating autoimmunity-suppressing cells identified
...derstood to result from immune cells attacking the bodys own cells instead of infectious agents such as vir...lls are finely tuned toward the recognition of the bodys own proteinsor selfand that a failure to make a complete repertoire of regulatory T cells may be an ...(Philadelphia, PA) In some ways, the bodys first line of defense can also be its worst enemy. The complement system is a series of biochemical reactions that activate in response to foreign molecules and is an important part of the immune system. Unfortunately, when it is activated at the wro...Veterinary researchers seek secret to reversing birth defects
...ubstance will alert and set into action one of the bodys frontline immune cells called "macrophages." These macrophages essentially engulf and break down what they see as foreign a process called phagocytosis. In the past, other researchers had hypothesized that the macrophages were acting directly on th...Scientists discover potent protein that prevents HIV infection
...stable, so it is less likely to be degraded by the bodys enzymes; can be made larger to avoid elimination b... kidneys; and modified such that it can escape the bodys immune response. The 5-Helix strategy may have broader application to a wide range of human viruses.......m a patients own body would not be rejected by the bodys immune system. While the results are very promising, researchers need to answer many remaining questions before marrow-derived neural cell therapies can be tested in humans. A key question is what growth factors and other signals prompt the bone ...ZymoGenetics researchers identify novel Interleukin that plays key role in immune system regulation
...oteins that appear to play a key role in the human bodys ability to fight disease. These proteins, designated Interleukin 21 (IL-21) and Interleukin 21 receptor (IL-21R), are members of an important class of naturally-occurring cytokine ligand-receptor pairs that are involved in the growth and activation ...... the broadest potential for giving rise to all the bodys tissues. However, recent studies have shown that cells with broad stem cell potential can be found in various adult tissues as well, including the bone marrow and nervous system. In the study at Childrens Hospital, researchers harvested mesenchymal...Recombinant protein may play key role in treating immunocompromised patients
...lls, works mainly by secreting antibodies into the bodys fluids. These antibodies seek and destroy the germs circulating in the bloodstream. However, antibodies are useless when it comes to penetrating cells. The task of attacking cells infected by viruses or deformed by cancer falls to the second arm o...