Warren Pharmaceuticals publishes results of preclinical evaluation
...go by Warren scientists that EPO crosses the blood brain barrier opened the way for development of protecti... "Any step forward in treatments for stroke, acute brain or spinal cord injury, or for chronic neurodegenerative diseases such as Alzheimer's disease, Parkin...OHSU scientists find gene influencing drug withdrawal
...nes, we can begin to study how this gene regulates brain circuits involved in drug dependence and withdrawal," said Kari Buck, Ph.D., associate professor of behavioral neuroscience and senior author of the study, which appears in the current issue of the journal Nature Neuroscience. The discovery also is m...Researchers discover how worms' noses sense oxygen
...helps us understand how NO receptors in muscle and brain are able to bind selectively to NO in low concentrations even when oxygen is present in far greater concentrations," he said. "This could have implications across a wide swath of biology, in cases where organisms need to bind NO in low concentrations...Structure solved at Scripps shows how one human protein reduces potency of chemotherapy
...ntists find ways to fight certain cancers, such as brain tumors, which express high levels of AGT making th...els of AGT. This enables cancers that arise in the brain to resist chemotherapy. Cancer cells in other parts of the body can also use AGT to escape chemother...Protein controls acid in cells by direct detection of volume changes, study finds
...re the blood supply is cut off to cardiac cells or brain cells, cells become very acidic. As the body's normal metabolism gets going again, the NHE1 system starts pumping out the accumulated acid, exchanging the acid for sodium. "It's such an active system that you can overload the cell with sodium," Dr. H...Combination of gene therapy and gene silencing prevents neurodegenerative disease
...ll fragments of genetic material (RNA) to critical brain cells of mice with a disorder that mimics the huma... and coordination. The gene therapy also protected brain cells from the destruction normally caused by the disease and prevented the build-up of protein clum...Severe depression associated with greater number of nerve cells in thalamus region of brain
...epression have more nerve cells in the part of the brain that controls emotion, researchers at UT Southwest...rain, the thalamus is involved with many different brain functions, including relaying information from other parts of the brain to the cerebral cortex. The ...National Parkinson Foundation designates UNC as 'Center of Excellence'
... Murrow is developing a nationally recognized deep brain stimulation program. Trster, brings recognized exp...research into the neurobehavioral outcomes of deep brain stimulation (DBS) and the mechanisms underlying language changes observed with DBS, in conjunction w...Microscopy scans show how brain cells process energy
...ng-standing debate among neuroscientists about how brain cells process energy -- while explaining what's re...generative diseases, such as Alzheimer's, wreak on brain cells. Multi-photon microscopy scans by Cornell University biophysicists of living brain tissue, as ...UNC scientists discover molecular pathway leading to nerve growth and regeneration
...em that portion of the nervous system outside the brain and spinal cord typically results in spontaneous ...findings may be important to understanding how the brain is wired, said Snider. "We think the findings may be relevant to axon growth in the brain." In the s...Infusion of two peptides acts to accelerate appetite satisfaction
...ween the gastrointestinal endocrine system and the brain in regulating food intake. The relationship is exp...nvey information about food intake and appetite to brain pathways that control eating. A team of researchers has added to this knowledge through their inves...Study: Artificial sweetener may disrupt body's ability to count calories
...esearch also will need to evaluate if the body and brain can be retrained to naturally measure calories after consuming artificial sweeteners or high-calorie beverages....Early dexamethasone exposure has long-term neurodevelopment, neuroendocrine effects
...conception. It is during this time that the human brain undergoes significant structural and functional tr...trued as prolonged social isolation. Somatic and brain growth: A regimen of decreasing dexamethasone exposure early in life has a lasting impact on the b...Carnegie Mellon U. imaging study reveals sex-based differences that persist as mice enter adulthood
...se brains to reveal fundamental differences in key brain structures, such as those important for emotions, ...that sex hormones alter the development of certain brain structures during puberty and that these effects persist into adulthood. The findings provide a ...A fly's taste experience is much like our own
...n brains, other senses typically are mapped in the brain by location or quality, but not both. Odors, for example, are perceived by the brain according to what, not where, they are. Touch, on the other hand, is mapped to the brain according t...Mutant mice lead to memory insights
...andel and colleagues also found alterations in the brain circuitry of the mutant mice that suggested impair...s. In those experiments, they administered both to brain slices from the mutant mice and to the mice themselves a drug that inhibits de-acetylation -- thereb...Evidence for fat hormone target in brain
...n affects a specific type of target neurons in the brain -- a prime link in the brain's regulation of the b...e produced by the body's fat tissues and to signal brain cells to reduce appetite and food intake and increase energy expenditures. Although researchers had ...Study sheds new light on genetic risk for Parkinson's disease
...zheimer's disease or poor recovery from stroke and brain injury." On the other hand, APOE-2 seems to occur with lower frequency in people with Alzheimer's disease and is linked with late onset of that disease's symptoms. The APOE type is linked to longevity and is more likely to be found in centena...Brain development and puberty may be key factors in learning disorders
...versity study is the first to suggest that delayed brain development and its interaction with puberty may b...hing learning disabilities from the perspective of brain development could potentially unite many seemingly disparate deficits observed in adults with learni...Researchers show 'clot-busting' at stroke site is viable option
...irst published evidence that aggressively treating brain blood clots at their source soon after symptoms st... in the leg that is guided through the neck to the brain and the site of the clot. Physicians at OSU and CWRU used a different clot-dissolving agent, urokina...