Researchers make promiscuous animals monogamous by manipulating genes
...relationships are involved in drug addiction. "The brain process of bonding with one's partner may be similar to becoming addicted to drugs: both activate reward circuits in the brain." The researchers' next step is to determine why there is extensive variability in behaviors among individuals within a sp...JCI table of contents, 15 June 2004
... Requires DNA Repair TITLE: Increased postischemic brain injury in mice deficient in uracil-DNA glycosylase AUTHOR CONTACT: Matthais Endres Charite-Universitatsmedizin Berlin, Berlin, Germany. Phone: +49-30-450-560-020; Fax: +49-30-450-560-932; E-mail: matthias.endres@charite.de View the PDF of this art...Conflicting views on embryonic and adult stem cells complicate research in stem cell therapeutics
...es specific to their point of origin. For example, brain and hematopoietic stem cells give rise only to neu...luding bone marrow, blood, adipose tissue, and the brain offsets their inability to differentiate into numerous types of tissues. Recent research has also de...Altered protein involved in a novel link to Alzheimer's disease
...ew findings of the presence of beta amyloid in the brain of a mouse that overproduces a protein called p25 .... With Dr. Tsai's discovery of beta amyloid in the brain of her mouse model, it is now evident that the overexpression of the p25 protein induces all three p...Existing drug may prevent brain injury and seizures in newborns
...eady approved by the FDA may protect newborns from brain injury and long-term neurologic problems caused by...ia-ischemia, the chemical glutamate accumulates in brain tissues. Glutamate binds to receptors on neurons and over-activates them, causing the brain cells t......ds of a nerve before the nerve is able to link the brain to each body part it controls. The study found t...a development gene named Hoxb1 worked in a mouse's brain but not in the developing facial tissues, nerves extended outward from the brain but failed to reach...Organization for Human Brain Mapping 2004 Annual Meeting
...s continue to characterize the field of functional brain imaging - the method by which brain activity can be observed in awake, behaving organisms, including human beings. The latest developme...Canine word-learning research published in Science
...dogs is remarkable. This ability suggests that the brain structures that support this kind of learning are not unique to humans, and may have formed the evolutionary basis of some of the advanced language abilities of humans," said Katrina Kelner, Science 's deputy editor for life sciences. The German tea...Drunken worms reveal a genetic basis of alcohol response
...differences between worm strains in the gene for a brain protein called NPR-1 explains differences in the w... as a neuronal receptor -- a molecular "socket" in brain cells into which plug proteins that affect signaling between brain cells. The human relati...Alzheimer's may leave some forms of memory intact
... studies we have done, it appears that a number of brain systems are more intact in Alzheimer's than we had...dings suggest that if we can help people use these brain systems optimally by providing the right kinds of cues or task instructions, we may be able to impro...Damaged genes in aging human brain provide clues to cognitive decline
Unraveling the mysteries of the aging brain is a major goal for brain science, especially given the exploding population of senior citizens and the obvious desire to pres...Thimerosal, found in childhood vaccines, can increase the risk of autism-like damage in mice
...ion of environment); Significant abnormalities in brain architecture, affecting areas subserving emotion and cognition; Increased brain size. These findings have relevance for identification of autism cases relating to environmental fac...Sex-specific differences in gene expression related to drug metabolism and hypertension
...ey, liver, and reproductive organs as well as in a brain region called the hypothalamus. "We looked for ge...s not only the case in the mouse, but in the human brain as well. "It is possible that sexual differences in the adult hypothalamus are mediated by a small n...Loss of circadian genes results in epilepsy
... vacuum cleaner. The researchers monitored brain electrical activity in the mice to confirm their observation that those mice lacking all three PAR bZip genes are prone to epileptic seizures. The recording of electroencephalograms (EEGs) during several days revealed that all of the triple knockout ...U. Iowa muscular dystrophy discovery may lead to new treatment approaches
...ther proteins and leads to muscle degeneration and brain defects in these muscular dystrophies. LARGE protein is mutated in patients with congenital muscular dystrophy 1D. In the Nature Medicine article, Campbell and his colleagues examined the effect of restoring expression of LARGE in mice that lacked th......nd leptin, hormones that convey information to the brain about the body's energy status and fat stores, have been linked in other studies to increased appetite and obesity. In addition, levels of ghrelin, a hormone thought to trigger appetite that normally declines following a meal, decreased less after ...Late invasion of infected cells into the brain causes HIV dementia say Temple researchers
...few macrophages that are infected and get into the brain and establish an infection in the resident microgl...increase in the number of total macrophages in the brain during HIV dementia," Rappaport says. "Why are there so many cells? We believe that the perivascul...VIB presents its annual results at BIO2004 in San Francisco
... sciences. In fact, this is an instance of reverse brain drain, because, after an international search, 3 Belgians proved to be the best candidates and they were eager to return to Flanders after successful careers abroad. VIB's innovative knowledge is a continuous source of new technologies and inventi...Protein engineered to detect nerve gas
...or proteins to sense glucose, lactate, TNT and the brain chemical serotonin. They began with proteins, called "periplasmic binding proteins," from the gut bacterium E. coli. These proteins are normally part of the bacterium's chemical-sensing system by which it detects nutrients. Such protein receptors det...Biologists discover nerve activity, not just genetics controls kinds of neurotransmitters produced
...y need to grow to the other side of the developing brain and form a synapse there. Genes can do a lot to sp... U.S. Surgeon General. "Focal stimulation of the brain to elicit changes in neurotransmitter production could have advantages over current drug treatments ...